2. Search Result
Search Result
Results for "

cv. Giza 134

" in MedChemExpress (MCE) Product Catalog:

68

Inhibitors & Agonists

1

Screening Libraries

2

Biochemical Assay Reagents

1

Inhibitory Antibodies

29

Natural
Products

2

Recombinant Proteins

2

Isotope-Labeled Compounds

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B0251
    Eplerenone
    5+ Cited Publications

    Epoxymexrenone

    		 Mineralocorticoid Receptor Endogenous Metabolite Cardiovascular Disease Cancer
    Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) .
    Eplerenone
  • HY-B0205
    Candesartan
    5+ Cited Publications

    CV 11974

    		 Angiotensin Receptor PPAR Cardiovascular Disease Endocrinology Cancer
    Candesartan (CV 11974) is an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. Candesartan has potent and long-lasting antihypertensive effects. Candesartan can be used for the research of hypertension, chronic heart failure (CHF) and Traumatic brain injury (TBI) .
    Candesartan
  • HY-129139
    Cyanidin-3-O-arabinoside
    1 Publications Verification

    		 Others Others
    Cyanidin-3-O-arabinoside is a pigment isolated from flowers of Rhododendron cv. Lems Stormcloud .
    Cyanidin-3-O-arabinoside
  • HY-118472
    Benazeprilat

    CGS 14831

    		 Drug Metabolite Endogenous Metabolite Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    Benazeprilat is an orally active and the active metabolite of benazepril, a carboxyl-containing ACE inhibitor with antihypertensive activity. Benazepril is a well-established antihypertensive agent, both in monoresearch and in combination with other classes of drugs including thiazide diuretics and calcium channel blockers. Benazepril is a first-line research in reducing various pathologies associated with CV risk and secondary end-organ damage .
    Benazeprilat
  • HY-17403
    Manidipine dihydrochloride
    3 Publications Verification

    CV-4093

    		 Calcium Channel NF-κB Infection Cardiovascular Disease Metabolic Disease Inflammation/Immunology
    Manidipine dihydrochloride is a third-generation, lipophilic, orally active and highly vasoselective calcium channel antagonist (IC50 = 2.6 nM in guinea-pig ventricular cells) and acts as an antihypertensive agent. Manidipine effectively reduces blood pressure as well as improving insulin sensitivity, renal protection, and antiatherosclerotic activity. Manidipine also exerts anti-inflammatory activity mediated by NF-κB and antiviral activity against many flavivirus and negative-strand RNA viruses through the inhibition of calcium channel. Manidipine is widely applied to research of cardiovascular, metabolic disease and infection .
    Manidipine dihydrochloride
  • HY-10397A
    MX1013
    1 Publications Verification

    CV1013; Z-VD-FMK

    		 Caspase Cancer
    MX1013 is a potent, irreversible dipeptide caspase inhibitor vith antiapoptotic activity. MX1013 inhibits recombinant human caspase 3 with an IC50 of 30 nM .
    MX1013
  • HY-112257
    S-23
    1 Publications Verification

    		 Androgen Receptor Metabolic Disease
    S-23 is an orally active selective androgen receptor modulator (SARM) with a Ki of 1.7 nM. S-23 induces androgen receptor (AR)-mediated transcriptional activation in CV-1 cells. S-23 increases prostate, seminal vesicle, and levator ani muscle weights in castrated rats .
    S-23
  • HY-109897
    CV-6209

    		Platelet-activating Factor Receptor (PAFR) Cardiovascular Disease
    CV-6209 is a potent antagonist of platelet activating factor (PAF). CV-6209 inhibits the PAF-induced aggregation of rabbit and human platelets, with IC50s of 75 nM and 170 nM, respectively. CV-6209 can inhibit PAF-induced hypotension in rats .
    CV-6209
  • HY-118020A
    Loliolide

    Loliolid; Digiprolactone

    		 Endogenous Metabolite Caspase PI3K Apoptosis Akt Sirtuin Reactive Oxygen Species (ROS) NF-κB MMP Neurological Disease Cancer
    Loliolide (Loliolid) is a β-carotene metabolite. Loliolide reduces caspase 3, 8, 9 expression, enhances PI3K, AKT, SIRT1, inhibits ROS, apoptosis, and blocks NF-κB p65 nuclear translocation. Loliolide protects mitochondria, reduces oxidative stress, and increases cell viability in neuroblastoma cells. Loliolide can be used for the research of UV-induced skin damage and Parkinson’s disease .
    Loliolide
  • HY-120161
    AS6

    3'-Hexylsulfanylabscisic acid

    		 ABA Receptor Phosphatase Others
    AS6 (3'-Hexylsulfanylabscisic acid) is a PYL antagonist with a Kd value of 0.48 μM for Arabidopsis PYL5. AS6 binds to PYL proteins, and its S-hexyl chain blocks PP2C binding via steric hindrance. AS6 alleviates the inhibitory effect of ABA on seed germination in Arabidopsis and lettuce .
    AS6
  • HY-164642
    Ribulose 1,5-bisphosphate

    RuBP

    		 Endogenous Metabolite Metabolic Disease
    Ribulose 1,5-bisphosphate (RUBP) is a vital photosynthetic intermediate and substrate. Ribulose 1,5-bisphosphate acts as both product and substrate for Thermococcus kodakarensis KOD1 R15Pi. Ribulose 1,5-bisphosphate tightly binds to inactive RuBP carboxylase sites in plant leaves.Ribulose 1,5-bisphosphate serves as the key substrate for CO2 fixation in photosynthesis. Ribulose 1,5-bisphosphate supports carboxylation and regeneration processes in photosynthesis. Ribulose 1,5-bisphosphate determines the dynamic transition temperature of photosynthetic control. Ribulose 1,5-bisphosphate can be used for photosynthesis and enzyme mechanism research .
    Ribulose 1,5-bisphosphate
  • HY-13736A
    Quinagolide hydrochloride

    CV205-502 hydrochloride

    		 Dopamine Receptor Akt Neurological Disease Cancer
    Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research of cancer .
    Quinagolide hydrochloride
  • HY-100679
    Pirlindole

    		Monoamine Oxidase Enterovirus Infection Neurological Disease
    Pirlindole is a selective and reversible MAO-A inhibitor . Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) .
    Pirlindole
  • HY-N13047
    Ningnanmycin

    		TMV SOD Infection
    Ningnanmycin is a plant antiviral agent. Ningnanmycin binds to specific residues on the TMV CP disc, inhibits CP assembly, disassembles the CP disc into monomers, and disrupts the structure of the TMV CP disc to reduce pathogenicity. Ningnanmycin binds to key amino acids of PVY CP, interferes with CP-CP interactions, inhibits CP assembly and virion formation, and blocks PVY replication. Ningnanmycin induces the expression of antiviral response genes PRXIIB, PRXIIE, PUB4 and PER42, thereby activating the host defense system. Ningnanmycin can be used in studies related to Tobacco Mosaic Virus infection and Potato Virus Y infection .
    Ningnanmycin
  • HY-103183
    CV1808

    2-Phenylaminoadenosine

    		 Adenosine Receptor Endogenous Metabolite Inflammation/Immunology
    CV1808 (2-Phenylaminoadenosine) is a non-selective A2 adenosine receptor (A2 AR) agonist with Kis of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively .
    CV1808
  • HY-W010254
    4′-Hydroxy-2′-methylacetophenone

    		Parasite Infection
    4′-Hydroxy-2′-methylacetophenone, an aroma compound of red wines, is isolated from cv. Bobal grape variety. 4′-Hydroxy-2′-methylacetophenone has ciliate toxicity. 4′-Hydroxy-2′-methylacetophenone inhibits the growth of T. pyriformis, with an IC50 of 0.65 mM .
    4′-Hydroxy-2′-methylacetophenone
  • HY-B0251R
    Eplerenone (Standard)
    Maximum Cited Publications
    8 Publications Verification

    Epoxymexrenone (Standard)

    		 Reference Standards Mineralocorticoid Receptor Endogenous Metabolite Cardiovascular Disease Cancer
    Eplerenone (Standard) is the analytical standard of Eplerenone. This product is intended for research and analytical applications. Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) .
    Eplerenone (Standard)
  • HY-W017448
    Mepiquat chloride

    N,N-Dimethylpiperidinium chloride; PIX

    		 Environmental Pollutants Biochemical Assay Reagents Others
    Mepiquat chloride (N,N-Dimethylpiperidinium chloride) is a systemic plant growth regulator. Mepiquat chloride reduces the activity of RuBP carboxylase. Mepiquat chloride decreases plant height, total length of vegetative and fruiting branches, and total leaf area of cotton. Mepiquat chloride reduces the net photosynthetic rate of cotton leaves. Mepiquat chloride promotes starch accumulation in cotton leaves without altering sucrose content .
    Mepiquat chloride
  • HY-B2007
    Fluazifop-P-butyl

    		Environmental Pollutants Acetyl-CoA Carboxylase Herbicide Metabolic Disease Inflammation/Immunology
    Fluazifop-P-butyl is an orally active herbicide and ACCase inhibitor. Fluazifop-P-butyl blocks the formation of malonyl-CoA, disrupts lipid synthesis in sensitive plants, and exhibits concentration-dependent phytotoxicity to non-target maize seedlings. Fluazifop-P-butyl induces oxidative stress in male Wistar rats, impairs their liver and kidney functions, and disrupts testicular function .
    Fluazifop-P-butyl
  • HY-Y0319B3
    Potassium acetate, meets analytical specification of Ph. Eur. BP E261

    		Biochemical Assay Reagents Others
    Potassium acetate, meets analytical specification of Ph. Eur. BP E261 is a high-purity grade reagent suitable for a wide range of research applications, particularly in pharmaceutical development, organic synthesis, and biochemistry .
    Potassium acetate, meets analytical specification of Ph. Eur. BP E261
  • HY-N3492
    Isoderrone

    		Others Others
    Isoderrone is a new isoflavone isolated from the methanol extractives from white lupin (cv. Kievskij Mutant) roots .
    Isoderrone
  • HY-153626
    Chlamydia pneumoniae-IN-1

    		Bacterial Antibiotic Infection Inflammation/Immunology
    Chlamydia pneumoniae-IN-1 (compound 55), a benzimidazole, shows high activity against the bacterium. Chlamydia pneumoniae-IN-1 has 99% inhibition of C. pneumoniae Growth at 10 μM, and has 95% inhibition effect on the viability of the host cells at 10 μM. Chlamydia pneumoniae-IN-1 inhibits the growth of the CV-6 strain with a MIC of 12.6 μM. Chlamydia pneumoniae-IN-1 has antichlamydial efficiency .
    Chlamydia pneumoniae-IN-1
  • HY-100679A
    Pirlindole mesylate

    		Monoamine Oxidase Enterovirus Infection Endocrinology
    Pirlindole mesylate is a selective and reversible MAO-A inhibitor. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) .
    Pirlindole mesylate
  • HY-19025
    CV-159

    		Calmodulin Inflammation/Immunology
    CV-159 is a unique dihydropyridine Ca 2+ antagonist with an anti-calmodulin (CaM) action, and has antiinflammatory activities.
    CV-159
  • HY-121232
    Delapril

    CV-3317

    		 Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    Delapril (CV-3317) is an orally active angiotensin I converting enzyme (ACE) inhibitor. Delapril has antihypertensive activity .
    Delapril
  • HY-B0205S
    Candesartan-d4

    CV-11974-d4

    		 Angiotensin Receptor Others
    Candesartan-d4 (CV-11974-d4) is the deuterium labeled Candesartan (HY-B0205). Candesartan (CV 11974) is an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. Candesartan has potent and long-lasting antihypertensive effects. Candesartan can be used for the research of hypertension, chronic heart failure (CHF) and Traumatic brain injury (TBI).
    Candesartan-d4
  • HY-B0205R
    Candesartan (Standard)

    CV 11974 (Standard)

    		 Reference Standards Angiotensin Receptor PPAR Cardiovascular Disease Endocrinology Cancer
    Candesartan (Standard) is the analytical standard of Candesartan. This product is intended for research and analytical applications. Candesartan (CV 11974) is an orally active angiotensin II AT1-Receptor blocker and PPAR-γ agonist. Candesartan has potent and long-lasting antihypertensive effects. Candesartan can be used for the research of hypertension, chronic heart failure (CHF) and Traumatic brain injury (TBI) .
    Candesartan (Standard)
  • HY-100268
    Xenalamine

    Xenazoic acid; CV58903

    		 Antibiotic Infection
    Xenalamine is a synthetic antiviral agent.
    Xenalamine
  • HY-16906
    T338C Src-IN-2

    		Src Cancer
    T338C Src-IN-2 is a mutant c-Src kinase inhibitor, with an IC50 of 317 nM against T338C c-Src, 57 nM against T338C/V323A c-Src, and 19 nM against T338C/V323S c-Src. T338C Src-IN-2 inhibits the kinase activity of endogenous cysteine gatekeeper MOK. T338C Src-IN-2 reduces global phosphotyrosine levels in v-Src-ES1-transformed NIH-3T3 cells .
    T338C Src-IN-2
  • HY-129529
    6-Hydroxyluteolin 7-glucoside

    		Others Inflammation/Immunology
    6-Hydroxyluteolin 7-glucoside is a glycoside. 6-Hydroxyluteolin 7-glucoside can be isolated from Tanacetum vulgare and C. chrvsanthus cv. Cream Beauty. 6-Hydroxyluteolin 7-glucoside can be used in inflammation research .
    6-Hydroxyluteolin 7-glucoside
  • HY-B0251S1
    Eplerenone-13C,d3

    Epoxymexrenone-13C,d3

    		 Isotope-Labeled Compounds Mineralocorticoid Receptor Endogenous Metabolite Cardiovascular Disease Cancer
    Eplerenone- 13C,d3 (Epoxymexrenone- 13C,d3) is 13C labeled Eplerenone. Eplerenone (Epoxymexrenone) is a selective, highly specific and orally active aldosterone blocker (SAB). Eplerenone also is a selective mineralocorticoid receptor antagonist (MRA) with IC50 value of 0.081 μM. Eplerenone can be used for the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) .
    Eplerenone-13C,d3
  • HY-168085
    CV-4-26

    		YAP Apoptosis Cancer
    CV-4-26 (Compound 22) is a covalent inhibitor of TEAD. CV-4-26 inhibits YAP/TEAD-based transcription, leading to the reduction of CTGF and CYR61 expression. CV-4-26 inhibits Huh7 and HepG2 cell colony formation, induces cell cycle arrest, and apoptosis. CV-4-26 shows antitumor activity against hepatocellular carcinoma (HCC) and hepatoblastoma (HB) .
    CV-4-26
  • HY-106062
    CV 3988

    		Platelet-activating Factor Receptor (PAFR) Others
    CV 3988 is a specific inhibitor of platelet-activating factor (PAF) .
    CV 3988
  • HY-119890
    Isbogrel

    CV-4151

    		 Prostaglandin Receptor Cardiovascular Disease Cancer
    Isbogrel (CV-4151) is a potent selective inhibitor of thromboxane A2 synthase. Isbogrel has oral activity and inhibits blood TXA2 generation with an ID50 value of 0.04 mg/kg .
    Isbogrel
  • HY-103183R
    CV1808 (Standard)

    2-Phenylaminoadenosine (Standard)

    		 Reference Standards Adenosine Receptor Endogenous Metabolite Inflammation/Immunology
    CV1808 (Standard) is the analytical standard of CV1808. This product is intended for research and analytical applications. CV1808?(2-Phenylaminoadenosine) is a non-selective A2?adenosine receptor (A2 AR) agonist with Kis of 76 and 1450 nM for A2A and A3 adenosine receptor subtypes, respectively .
    CV1808 (Standard)
  • HY-13736
    Quinagolide

    CV205-502

    		 Dopamine Receptor Neurological Disease
    Quinagolide (CV205-502) is a non-ergot dopamine D(2) receptor agonist that promotes dopamine activity. Quinagolide has shown effectiveness in modulating endocrine function, particularly in inhibiting disorders associated with dopamine deficiency. Quinagolide is used to suppress hyperprolactinemia and corresponding clinical symptoms, showing good efficacy. Quinagolide's biological activity enables its use as an important research compound in drug isolation and analysis .
    Quinagolide
  • HY-145516
    Desmethyl Bosentan

    Ro 47-8634

    		 Drug Metabolite Cytochrome P450 Metabolic Disease
    Desmethyl bosentan is an active metabolite of the endothelin receptor antagonist bosentan (HY-A0013).1 Desmethyl bosentan (25 μM) activates the pregnane X receptor (PXR) in CV-1 monkey kidney cells expressing the human receptor in a reporter assay.
    Desmethyl Bosentan
  • HY-N10192
    Aculene D

    		Endogenous Metabolite Bacterial Infection
    Aculene D, a fungal metabolite, shows quorum sensing (QS) inhibitory activity against Chromobacterium violaceum CV026, and could significantly reduce violacein production in N-hexanoyl-l-homoserine lactone (C6-HSL) induced C. violaceum CV026 cultures at sub-inhibitory concentrations .
    Aculene D
  • HY-N3758
    Dihydrosesamin

    		Cytochrome P450 Others
    Dihydrosesamin is a Lignans product that can be isolated from the young shoots of Chamaecyparis obtusa cv. Breviramea. .
    Dihydrosesamin
  • HY-N12270
    Petanin chloride

    		Others Others
    Petanin (chloride) is a p-coumaroyl anthocyanin from the tuber epidermis of colored potato (Solanum tuberosum L. cv JAYOUNG) .
    Petanin chloride
  • HY-N3496
    Isochandalone

    		Others Others
    Isochandalone is a new isoflavone isolated from the methanol extractives from white lupin (cv. Kievskij Mutant) roots .
    Isochandalone
  • HY-N9222
    9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A

    		Others Others
    9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A is a Diterpenoids product that can be isolated from the stem-barks of Taxus baccata L. cv. stricta. .
    9-Deacetyl-9-benzoyl-10-debenzoyltaxchinin A
  • HY-137396
    6β-Hydroxy Eplerenone

    		Endogenous Metabolite Cardiovascular Disease
    6β-Hydroxy Eplerenone is a metabolite of Eplerenone (HY-B0251). 6β-Hydroxy Eplerenone plays an important role in the research of hypertension, atherosclerosis, chronic systolic heart failure (HF) and cardiovascular (CV) .
    6β-Hydroxy Eplerenone
  • HY-100679R
    Pirlindole (Standard)

    		Reference Standards Monoamine Oxidase Enterovirus Infection Neurological Disease
    Pirlindole (Standard) is the analytical standard of Pirlindole. This product is intended for research and analytical applications. Pirlindole is a selective and reversible MAO-A inhibitor . Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3) .
    Pirlindole (Standard)
  • HY-N9033
    9-Deacetyl-9-benzoyl-10-debenzoyl-4β,20-epoxytaxchinin A

    		Others Others
    9-Deacetyl-9-benzoyl-10-debenzoyl-4β,20-epoxytaxchinin A is a Diterpenoids product that can be isolated from the stem-barks of Taxus baccata L. cv. stricta. .
    9-Deacetyl-9-benzoyl-10-debenzoyl-4β,20-epoxytaxchinin A
  • HY-19064
    CV-6504

    		Prostaglandin Receptor Lipoxygenase Cardiovascular Disease Inflammation/Immunology Cancer
    CV-6504 is a dual inhibitor of TXA2 synthase and 5-lipoxygenase. CV-6504 can scavenge ROS and exhibit antitumor activity. CV-6504 can be used for the researches of cancer, inflammation and cardiovascular disease .
    CV-6504
  • HY-106797
    CV 3611

    		SOD Xanthine Oxidase Cardiovascular Disease Inflammation/Immunology Cancer
    CV 3611 is a potent and orally active free radical scavenger. CV 3611 shows anti-inflammatory, antiarrhythmic and anticancer effects. CV 3611 can be used for the researches of cancer, inflammation and cardiovascular disease, such as hepatocellular carcinoma and acute pancreatitis .
    CV 3611
  • HY-157172
    MorHap

    		Integrin Infection Neurological Disease
    MorHap is a heroin hapten. MorHap conjugated to tetanus toxoid (TT), palm-CV2, and to monophosphoryl lipid A (MPLA)-containing liposomes partially blocks heroin-induced analgesia and hyperlocomotion in mice. MorHap designed conjugates also significantly inhibits HIV-1 binding to α4β7 receptors. MorHap can be used in research to develop vaccines related to heroin addiction and HIV-1 infection .
    MorHap
  • HY-118472R
    Benazeprilat (Standard)

    CGS 14831 (Standard)

    		 Drug Metabolite Reference Standards Endogenous Metabolite Angiotensin-converting Enzyme (ACE) Cardiovascular Disease
    Benazeprilat (Standard) is the analytical standard of Benazeprilat. This product is intended for research and analytical applications. Benazeprilat is an orally active and the active metabolite of benazepril, a carboxyl-containing ACE inhibitor with antihypertensive activity. Benazepril is a well-established antihypertensive agent, both in monoresearch and in combination with other classes of drugs including thiazide diuretics and calcium channel blockers. Benazepril is a first-line research in reducing various pathologies associated with CV risk and secondary end-organ damage .
    Benazeprilat (Standard)
  • HY-N3103R
    p-Coumaric Acid Ethyl Ester (Standard)

    Ethyl (E)-p-hydroxycinnamate (Standard); Ethyl trans-4-hydroxycinnamate (Standard)

    		 Reference Standards Drug Metabolite Inflammation/Immunology
    Benazeprilat (Standard) is the analytical standard of Benazeprilat. This product is intended for research and analytical applications. Benazeprilat is an orally active and the active metabolite of benazepril, a carboxyl-containing ACE inhibitor with antihypertensive activity. Benazepril is a well-established antihypertensive agent, both in monoresearch and in combination with other classes of drugs including thiazide diuretics and calcium channel blockers. Benazepril is a first-line research in reducing various pathologies associated with CV risk and secondary end-organ damage .
    p-Coumaric Acid Ethyl Ester (Standard)

Inquiry Online

Your information is safe with us. * Required Fields.

Salutation

  

Country or Region *

Applicant Name *

 

Organization Name *

Department *

     

Email Address *

 

Product Name *

Cat. No.

  

Requested quantity *

Phone Number *

     

Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: