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Cat. No.: HY-153626

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Chlamydia pneumoniae-IN-1

Chlamydia pneumoniae-IN-1 (compound 55), a benzimidazole, shows high activity against the bacterium. Chlamydia pneumoniae-IN-1 has 99% inhibition of C. pneumoniae Growth at 10 μM, and has 95% inhibition effect on the viability of the host cells at 10 μM. Chlamydia pneumoniae-IN-1 inhibits the growth of the CV-6 strain with a MIC of 12.6 μM. Chlamydia pneumoniae-IN-1 has antichlamydial efficiency.

For research use only. We do not sell to patients.

CAS No.: 518010-44-1
Formula: C₁₉H₁₅N₃OS
Molecular Weight:333.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Chlamydia pneumoniae-IN-1 Chemical Structure

CAS No.: 518010-44-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All Antibiotic Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
NIH3T3	IC₅₀	16.7 μM Compound: 22	Cytotoxicity against mouse NIH/3T3 cells assessed as viability after 48 hrs by alamarBlue assay Cytotoxicity against mouse NIH/3T3 cells assessed as viability after 48 hrs by alamarBlue assay	[PMID: 25827525]
THP-1	IC₅₀	10.5 μM Compound: 22	Antileishmanial activity against Leishmania donovani MHOM/SD/1962/1S-Cl2d infected THP1 cells assessed as inhibition of intracellular axenic amastigote after 48 hrs at 50 uM by Bright-Glo luciferase assay Antileishmanial activity against Leishmania donovani MHOM/SD/1962/1S-Cl2d infected THP1 cells assessed as inhibition of intracellular axenic amastigote after 48 hrs at 50 uM by Bright-Glo luciferase assay	[PMID: 25827525]

Chemical Information

CAS No. 518010-44-1
Molecular Weight 333.41
Formula C₁₉H₁₅N₃OS
SMILES

O=C(C1=CC=CS1)NC2=CC=CC(C3=NC4=CC=C(C)C=C4N3)=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Leena Keurulainen, et al. Design and synthesis of 2-arylbenzimidazoles and evaluation of their inhibitory effect against Chlamydia pneumonia. J Med Chem. 2010 Nov 11;53(21):7664-74. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Chlamydia pneumoniae-IN-1

All Antibiotic Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Chlamydia pneumoniae-IN-1 Related Classifications

HY-153626 Related Classifications