Glyceollin II
Glyceollin II is a glyceollin found in soybean cotyledons (CY. Harosoy 63) inoculated with Phytophthora megaspenna f.sp. glycinea race 1. Glyceollin II inhibits the radial mycelial growth of P. megasperma f.sp. gbcinea race 1. Glyceollin II inhbiits zoospore germination (ED50 = 7 μg/mL) and causes zoospores to burst. Glyceollin II can be used for the research of Phytophthora megasperma f.sp. glycinea infection in soybeans.
For research use only. We do not sell to patients.
- CAS No.: 67314-98-1
- Formula: C20H18O5
- Molecular Weight:338.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Glyceollin II (24 h) inhibits radial mycelial growth of Phytophthora megasperma f.sp. glycinea race 1 with ED50 values of 61.6 μg/mL and 52.1 μg/mL, and causes 56.1% growth inhibition at 75 μg/mL[1].
Glyceollin II (0-40 μg/mL; 3 h) is the most potent glyceollin isomer against Phytophthora megasperma f.sp. glycinea race 1 zoospore germination, with an ED50 of 7.0 ± 1.0 μg/mL and ED90 of 13.9 ± 1.9 μg/mL, and induces bursting of non-germinated zoospores[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 67314-98-1
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Molecular Weight 338.35
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Formula C20H18O5
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SMILES
O[C@@]12COC3=CC4=C(C=CC(C)(C)O4)C=C3[C@]1([H])OC5=CC(O)=CC=C52
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
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Filamentous Fungal Mold Culture and Sporulation
Filamentous fungal mold culture and sporulation assays grow hyphae under defined nutritional and environmental conditions until asexual spores, commonly conidia, are produced; the main readouts are colony growth, sporulation onset, conidial yield, conidial morphology, viability, and, when relevant, downstream infectivity or stress phenotype.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Glyceollin II Related Classifications
HY-N18032 Related Classifications
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Keywords
- Glyceollin II
- 67314-98-1
- Others
- half-strength clarified V8 juice agar
- phytoalexin
- soybean hypocotyl extract agar
- Phytophthora megasperma f.sp. glycinea race 1
- mycelial radial growth
- zoospores
- soybean (Glycine max L. cv. Harosoy 63) cotyledons
- zoospore germination
- pterocarpinoid
- soybeans
- Inhibitor
- inhibitor
- inhibit