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Results for "

12a

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Antibiotic (7) Apoptosis (3) Arginase (1) Aryl Hydrocarbon Receptor (1) Autophagy (1) Bacterial (9) Biochemical Assay Reagents (1) C-type Lectin-like Receptors (CTLRs) (1) Calcium Channel (2) Cholinesterase (ChE) (4) Complement System (1) CXCR (1) DNA/RNA Synthesis (1) Dopamine Receptor (1) Drug Intermediate (1) Endogenous Metabolite (2) Epigenetic Reader Domain (1) FATP (1) FLAP (1) Fluorescent Dye (1) Fungal (1) HDAC (1) Hedgehog (1) Histamine Receptor (1) HIV (3) JAK (1) Kinesin (1) Lipoxygenase (1) Microtubule/Tubulin (1) MMP (7) Monoamine Oxidase (1) mRNA (2) NO Synthase (1) Nucleoside Antimetabolite/Analog (1) Paraptosis (1) Parasite (8) PARP (1) Reactive Oxygen Species (ROS) (1) Reference Standards (6) Sigma Receptor (1) Small Interfering RNA (siRNA) (29) Smo (1) Src (1) TNF Receptor (1)
By Research Areas:	Cancer (19) Cardiovascular Disease (2) Infection (17) Inflammation/Immunology (9) Metabolic Disease (6) Neurological Disease (11)
Oligonucleotides:	Rat Pre-designed siRNA Sets (5) Mouse Pre-designed siRNA Sets (5) mRNA (2) Human Pre-designed siRNA Sets (19) siRNAs (29) Interleukin & Receptors (1)

Inhibitors & Agonists

Fluorescent Dye

Peptides

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Antibodies

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0565

Doxycycline Maximum Cited Publications 173 Publications Verification	MMP Bacterial Antibiotic Parasite	Infection Neurological Disease Inflammation/Immunology Cancer
Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity .

HY-N0565B

Doxycycline hyclate Maximum Cited Publications 173 Publications Verification Doxycycline hydrochloride hemiethanolate hemihydrate; WC2031	Antibiotic MMP Bacterial Parasite	Infection Neurological Disease Inflammation/Immunology Cancer
Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor. Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hyclate can be used to construct gene expression regulation models .

HY-N0565A

Doxycycline hydrochloride Maximum Cited Publications 173 Publications Verification	MMP Bacterial Antibiotic Parasite	Infection Neurological Disease Inflammation/Immunology Cancer
Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity. Doxycycline hydrochloride can be used to construct gene expression regulation models .

HY-P99361

Enavatuzumab PDL192; ABT-361; Anti-TNFRSF12a/TWEAKR/CD266 Reference Antibody (enavatuzumab)	TNF Receptor	Cancer
Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK). TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo .

HY-B2209

Hydroxocobalamin 3 Publications Verification Vitamin B12a	Endogenous Metabolite	Neurological Disease Metabolic Disease
Hydroxocobalamin (Vitamin B12a) is a cyanide antidote. Hydroxocobalamin can decrease the cell and plasma cyanide concentrations and increase survival rate in acute cyanide poisoning. Hydroxocobalamin can improve newborn Cbl-C defect-induced metabolic profile and neurocognitive outcome. Hydroxocobalamin can normalize Vitamin B₁₂ deficiency. Hydroxocobalamin can induce acute kidney injury. Hydroxocobalamin can be used for the researches of metabolic and neurological disease .

HY-B2209A

Hydroxocobalamin monohydrochloride 3 Publications Verification Vitamin B12a monohydrochloride	Endogenous Metabolite	Metabolic Disease
Hydroxocobalamin monohydrochloride (Vitamin B12a monohydrochloride) is an injectable naturally occurring form of vitamin B12 with a favorable adverse effect profile, used as a dietary supplement in the treatment of vitamin B12 deficiency including pernicious anemia .

HY-B2209B

Hydroxocobalamin acetate 3 Publications Verification Vitamin B12a acetate	NO Synthase	Cardiovascular Disease Metabolic Disease
Hydroxocobalamin acetate is an injectable natural vitamin B12. Hydroxocobalamin acetate binds to NO. Hydroxocobalamin acetate detoxifies Cyanide and NaSH. Hydroxocobalamin acetate reduces hypotension. Hydroxocobalamin acetate is used in research related to vitamin B12 deficiency, including pernicious anemia .

HY-141700

FATP1-IN-2 2 Publications Verification	FATP	Metabolic Disease
FATP1-IN-2 (compound 12a), an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC₅₀=0.43 μM, mouse IC₅₀=0.39 μM) .

HY-144339

AhR agonist 2 1 Publications Verification	Aryl Hydrocarbon Receptor	Others
AhR agonist 2 (Compound 12a) is a potent agonist of aryl hydrocarbon receptor (AhR) with an EC₅₀ of 0.03 nM. AhR agonist 2 induces rapid nuclear enrichment of AhR, triggers the transcription of downstream genes and promote skin barrier repair. AhR agonist 2 has the potential for the research of psoriasis .

HY-N0565AR

Doxycycline hydrochloride (Standard)	Reference Standards MMP Bacterial Antibiotic Parasite	Infection Cancer
Doxycycline (hydrochloride) (Standard) is the analytical standard of Doxycycline (hydrochloride). This product is intended for research and analytical applications. Doxycycline hydrochloride, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hydrochloride shows antibacterial activity and anti-cancer cell proliferation activity [4] .

HY-N0565R

Doxycycline (Standard)	Reference Standards MMP Bacterial Antibiotic Parasite	Infection Cancer
Doxycycline (Standard) is the analytical standard of Doxycycline. This product is intended for research and analytical applications. Doxycycline, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline shows antibacterial activity and anti-cancer cell proliferation activity [4] .

HY-N0565BR

Doxycycline hyclate (Standard) Doxycycline hydrochloride hemiethanolate hemihydrate (Standard); WC2031 (Standard)	Reference Standards Antibiotic MMP Bacterial Parasite	Infection Cancer
Doxycycline hyclate (Standard) is the analytical standard of Doxycycline hyclate. This product is intended for research and analytical applications. Doxycycline hyclate, an antibiotic, is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor . Doxycycline hyclate shows antibacterial activity and anti-cancer cell proliferation activity .

HY-133034

NRP1 antagonist 1	Complement System	Cancer
NRP1 antagonist 1 (compound 12a) is a potent NRP1 antagonist with an IC₅₀ of 19.1 μM. NRP1 antagonist 1 has the potential for cancer research .

HY-153790

FEN1-IN-5	FLAP	Cancer
FEN1-IN-5 (compound 12A) is a potent inhibitor of Flap endonuclease-1 (FEN1, *IC₅₀*=12 nM), involving in DNA repair .

HY-E70220

AsCas12a Nuclease	Biochemical Assay Reagents	Others
AsCas12a Nuclease is a nuclease, and can specifically cutting double-stranded DNA. AsCas12a Nuclease can be used for gene edited study .

HY-P991453

Anti-CD371/CLEC12A Antibody (H6e7)	C-type Lectin-like Receptors (CTLRs)	Cancer
Anti-CD371/CLEC12A Antibody (H6e7) is a human monoclonal antibody (mAb) targeting *CD371/CLEC12A*. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

HY-D2331

*ZL-12A* probe**	DNA/RNA Synthesis Fluorescent Dye	Others
ZL-12A probe is a "stereoprobe "that can promote the degradation of TFIIH helicase ERCC3. ZL-12A degrades ERCC3 by covalently modifying C342 .

HY-174642

Human IL12A mRNA	mRNA	Inflammation/Immunology
Human IL12A mRNA encodes the human interleukin 12A (IL12A) protein, a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL12A is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells.

HY-N8276

Ro 3-1314 9a,12a-Octadecadiynoic acid	Lipoxygenase	Metabolic Disease Inflammation/Immunology
Ro 3-1314 (9a,12a-Octadecadiynoic acid) is a plant lipoxygenase inhibitor. Ro 3-1314 is a linoleic acid metabolism inhibitor. Ro 3-1314 stimulates the antigen-induced contraction of guinea-pig tracheal spirals and the immunological release of slow reacting substance of anaphylaxis (SRS-A) from actively sensitized guinea-pig lung fragments .

HY-RS14803

TNFRSF12A Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
TNFRSF12A Human Pre-designed siRNA Set A contains three designed siRNAs for TNFRSF12A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

TNFRSF12A Human Pre-designed siRNA Set A TNFRSF12A Human Pre-designed siRNA Set A

HY-RS13003

SLC12A8 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
SLC12A8 Human Pre-designed siRNA Set A contains three designed siRNAs for SLC12A8 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

SLC12A8 Human Pre-designed siRNA Set A SLC12A8 Human Pre-designed siRNA Set A

HY-47882

*(S)-9-Hydroxy-8-methoxy-12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-one*	Drug Intermediate	Others
(S)-9-Hydroxy-8-methoxy-12a,13-dihydro-6H-benzo[5,6][1,4]diazepino[1,2-a]indol-6-one is a drug intermediate for synthesis of various active compounds.

HY-144286

CXCR4 antagonist 3	CXCR	Infection
CXCR4 antagonist 3 (compound 12a) is a potent antagonist of CXCR4 with an IC₅₀ of 11 nM. CXCR4 antagonist 3 is a congener of TIQ15. CXCR4 antagonist 3 demonstrates the best overall properties including CXCR4 antagonism, CYP 2D6 inhibition, metabolic stability, and permeability. CXCR4 antagonist 3 has the potential for the research of human immunodeficiency virus .

HY-144324

AChE-IN-6	Cholinesterase (ChE)	Neurological Disease
AChE-IN-6 (Compound 12a) is an optimal multifunctional ligand with significant inhibition of AChE (EeAChE, IC₅₀ = 0.20 μM; HuAChE, IC₅₀ = 37.02 nM) and anti-Aβ activity (IC₅₀ = 1.92 μM for self-induced Aβ1-42 aggregation; IC₅₀ = 1.80 μM for disaggregation of Aβ1-42 fibrils; IC₅₀ = 2.18 μM for Cu2+-induced Aβ1-42 aggregation; IC₅₀ = 1.17 μM for disaggregation of Cu2+-induced Aβ1-42 fibrils). AChE-IN-6 has the potential for the research of Alzheimer's disease .

HY-N3712

Dehydrodeguelin 6a,12a-Dehydrodeguelin	Others	Others
Dehydrodeguelin (6a,12a-Dehydrodeguelin) is a nature product that could be isolated from the leaves of Amorpha fruticosa L .

HY-N3718

*6a,12a-Dehydro-α-toxicarol*	Others	Others
6a,12a-Dehydro-α-toxicarol is a natural product that can be isolated from Amorpha fruticosa .

HY-W192171

BRD4 Inhibitor-34	Epigenetic Reader Domain	Cancer
BRD4 Inhibitor-34 (Compound 12a) is a BRD4 inhibitor with an IC₅₀ of 24 μM .

HY-162615

Antibacterial agent 225	Fungal	Infection Inflammation/Immunology
Antibacterial agent 225 (compound 12a-2) simultaneously exerts excellent bifunctional effects of fungal inhibition and immune activation .

HY-159173

AChE-IN-71	Cholinesterase (ChE)	Neurological Disease
AChE-IN-71 (compound 12A) is a AChE inhibitor. AChE-IN-71 can be used in the study of Alzheimer’s disease .

HY-149336

D1R antagonist 1	Dopamine Receptor	Neurological Disease
D1R antagonist 1 (compound 12a) is a D1R antagonist, involved in G-protein- and β-arrestin-based signaling .

HY-150567

SMO-IN-3	Smo Hedgehog	Cancer
SMO-IN-3 (compound 12a) is a potent smoothened (SMO) inhibitor with an IC₅₀ value of 34.09 nM for hedgehog (Hh) signaling pathway. SMO-IN-3 has antiproliferative activity against human medulloblastoma cell line Daoy. Anticancer activity .

HY-156298

PARP1-IN-16	PARP Apoptosis	Cancer
PARP1-IN-16 (compound 12a) is a potent PARP1 inhibitor, with an IC₅₀ of 1.89 nM. PARP1-IN-16 can arrest the cell cycle in S phase and induce apoptosis in HCT-116 cells .

HY-145831

sEH/AChE-IN-1	Cholinesterase (ChE)	Neurological Disease Inflammation/Immunology
sEH/AChE-IN-1 (Compound 12a) is a dual inhibitor of the enzymes soluble epoxide hydrolase (sEH) and acetylcholinesterase (AChE). sEH/AChE-IN-1 provides cumulative effects against neuroinflammation and memory impairment. sEH/AChE-IN-1 has the potential for the research of Alzheimer's disease (AD) .

HY-170850

MKLP2-IN-1	Kinesin	Cancer
MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 with good oral bioavailability. MKLP2-IN-1 inhibits the microtubule-stimulated ATPase activity of recombinant MKLP2 in vitro and suppresses tumor growth in a mouse Calu-6 lung cancer model .

HY-147953

MAO-B-IN-13	Monoamine Oxidase	Neurological Disease
MAO-B-IN-13 (compound 12a) is a highly potent, reversible and blood-brain barrier (BBB) penetrant MAO-B inhibitor with an IC₅₀ value of 10 nM. MAO-B-IN-13 has neuroprotective and antioxidant activity. MAO-B-IN-13 can be used for researching Parkinson’s disease .

HY-151357

MraY-IN-3	Bacterial	Infection
MraY-IN-3 (12a) is a potent bacterial translocase MraY inhibitor with an IC₅₀ value of 140 µM. MraY-IN-3 acts on E. coli K12, B. subtilis W23 and P. fluorescens Pf-5 with the MIC₅₀ values of 7 µg/mL, 12 µg/mL, and 46 µg/mL, respectively .

HY-163278

Lck-IN-2	Src Apoptosis	Cancer
Lck-IN-2 (compound 12a) is an inhibitor of Lymphocyte-specific protein tyrosine kinase (Lck) with IC₅₀ of 10.6 nM. Lck-IN-2 reveals efficacy in colon cancer cells with GI₅₀s of 0.24-1.26 μM. Lck-IN-2 exhibits an apoptotic effect in Colo201 cells .

HY-173041

Arginase inhibitor 9	Arginase	Inflammation/Immunology
Arginase inhibitor 9 (Compound 12a) is an arginase inhibitor with IC₅₀ values of 9 μM and 55 μM for bovine and human arginase I, respectively. Arginase inhibitor 9 exhibits antioxidant activity and can scavenge free radicals. Additionally, Arginase inhibitor 9 can effectively regulate the levels of collagen and procollagen, exerting an anti-fibrotic effect .

HY-161139

JAK1-IN-14	JAK	Inflammation/Immunology
JAK1-IN-14 (Compound 12a) is a potent and selective JAK1 inhibitor. JAK1-IN-14 inhibits JAK1 and JAK2 with an IC₅₀ value of 12.6 nM and 135 nM. JAK1-IN-14 suppresses hepatic fibrosis levels and can be used for the research of liver fibrosis and inflammatory diseases .

HY-144728

MraY-IN-3 hydrochloride	Bacterial	Infection
MraY-IN-1 (compound 12a) is a potent MraY inhibitor with an IC₅₀ value of 140 μM. MraY-IN-1 has antimicrobial activity against Escherichia coli K12, Bacillus subtilis W23 and Pseudomonas fluorescens Pf-5 with MIC₅₀s of 7 µg/mL, 12 µg/mL and 46 µg/mL, respectively. MraY-IN-1 can be used for researching anti-bacteria .

HY-159149

Antitumor agent-182	Reactive Oxygen Species (ROS) Apoptosis	Cancer
Antitumor agent-182 (Compound 12a) decreases mitochondrial membrane potential (MMP) and enhances ROS levels. Antitumor agent-182 arrests the cell cycle at G0/G1 phase, induces apoptosis in HeLa. Antitumor agent-182 inhibits the proliferation of HeLa, PC-3 and HCT-15 with IC₅₀s of 8.83, 10.07 and 7.84 μM, respectively .

HY-146018

HIV-1 inhibitor-23	HIV	Infection
HIV-1 inhibitor-23 (compound 12a) is a highly potent HIV-1 non-nucleoside reverse transcriptase inhibitor, with EC₅₀s of 24.9 nM and 10.4 nM for HIV-1 WT and HIV-1 K103N, respectively. HIV-1 inhibitor-23 has low cytotoxicity (CC₅₀ > 221 μM) and a favorable in vitro microsomal stability .

HY-149578

Tubulin/HDAC-IN-3	Microtubule/Tubulin HDAC	Cancer
Tubulin/HDAC-IN-3 (compound 12a) is a potent tubulin/HDAC dual inhibitor. Tubulin/HDAC-IN-3 effectively disrupts tubulin polymerization (IC₅₀: 5.4 μM). Tubulin/HDAC-IN-3 exhibits potent HDAC1/8 inhibitory activities, with IC₅₀ values of 0.155 and 0.177 μM, respectively. Tubulin/HDAC-IN-3 works through blocking cellular cycle, inducing apoptosis and inhibiting colony formation .

HY-149779

RyR2 stabilizer-1	Calcium Channel	Cardiovascular Disease
RyR2 stabilizer-1 (compound 12a) is a potent RyR2 stabilizer and SERCA2a activator with EC₅₀s of 2.7 μM for RyR2 and 383 nM for SERCA2. RyR2 stabilizer-1 inhibits Ca ²⁺ leakage from the SR RyR2 while promoting SERCA2 to pump Ca ²⁺ back to SR, which make RyR2 stabilizer-1 possible to prevent cardiac arrhythmias .

HY-170783

DXR-IN-4	Parasite	Infection
DXR-IN-4 (Compound 12a) is the inhibitor for 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR). DXR-IN-4 inhibits DXR in Plasmodium falciparum Pf DXR, Escherichia coli Ec DXR, and Mycobacterium tuberculosis Mt DXR with IC₅₀s of 18, 4.9 and 89 nM, respectively. DXR-IN-4 exhibits antimalarial activity that inhibits P. falciparum strains 3D7 and Dd2 with IC₅₀ of 11 μM and 12 μM .

HY-146019

HIV-1 inhibitor-24	HIV	Infection
HIV-1 inhibitor-24 (compound S-12a) is a highly potent HIV-1 reverse transcriptase, with an IC₅₀ value of 9.5 nM. HIV-1 inhibitor-24 has high antiretroviral activity against WT HIV-1 with an EC₅₀ of 1.6 nM, and exhibits relatively low cytotoxicity with a CC₅₀ of 9.07 μM in MT-4 cells. HIV-1 inhibitor-24 is well tolerated at a dose of 2 g/kg in mice and has a significant cardiovascular safety .

HY-Z2775R

(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity） (Standard)	Reference Standards
(6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity） (Standard) is the analytical standard of (6aR,6bS,7S,8aS,8bS,11aR,12aS,12bS)-7-hydroxy-8b-(2-hydroxyacetyl)-6a,8a,10-trimethyl-6a,6b,7,8,8a,8b,11a,12,12a,12b-decahydro-1H-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-4(2H)-one (Budesonide Impurity）. This product is intended for research and analytical applications.

HY-149335

Sigma-1 receptor antagonist 5	Sigma Receptor Histamine Receptor	Neurological Disease
Sigma-1 receptor antagonist 5 (compound 12)，a 4-pyridylpiperidine derivative with analgesic activity，is an antagonist of sigma receptor (Ki=4.5 nM (σ1R)，10 nM (σ2R)) and histamine H3 (hH₃R，Ki=7.7 nM，IC₅₀=215 nM). Sigma-1 receptor antagonist 5 suppresses Capsaicin-induced nociception with antinociceptive activity and shows potent efficacy in nociceptive and neuropathic pain models .

HY-N9651

12a-Hydroxydalpanol	Others	Cancer
12a-Hydroxydalpanol is a rotenoid cytotoxic agent found in Amorpha fruticosa. 12a-Hydroxydalpanol exerts cytotoxic effects by inhibiting tumor cell proliferation. 12a-Hydroxydalpanol is promising for research of cancers .

HY-146019A

HIV-1 inhibitor-25	HIV	Infection
HIV-1 inhibitor-25 (compound R-12a) is a highly potent HIV-1 reverse transcriptase, with an IC₅₀ value of 0.1061 μM. HIV-1 inhibitor-25 has high antiretroviral activity against WT HIV-1 with an EC₅₀ of 13.6 nM, and exhibits relatively low cytotoxicity with a CC₅₀ of 33.13 μM in MT-4 cells. HIV-1 inhibitor-25 also has inhibitory activity against HIV-1 mutant strains (L100I, K103N, Y181C, Y188L, E138K, F227L+V106A) with EC₅₀ of 0.1961 ~ 5.8136 μM. HIV-1 inhibitor-25 can be used for researching AIDS .

Cat. No.	Product Name	Target	Research Area

HY-P5319

MCaE12A	Calcium Channel	Others
MCaE12A is a high-affinity modulator of RyR2 and increases RyR2 sensitivity to cytoplasmic calcium concentrations promoting channel opening. MCaE12A acts as an important tool for RyR2 structure-to-function studies as well as for manipulating Ca2+ homeostasis and dynamic of cardiac cell .

Cat. No.	Product Name	Target	Research Area	Image

HY-P99361

Enavatuzumab PDL192; ABT-361; Anti-TNFRSF12a/TWEAKR/CD266 Reference Antibody (enavatuzumab)	TNF Receptor	Cancer
Enavatuzumab (PDL192; ABT-361) is a humanized IgG1 monoclonal antibody targeting the receptor of TNF-like weak inducer of apoptosis (TWEAK). TWEAK (Fn14; TNFRSF12A), the natural ligand of the TWEAK receptor (TweakR), stimulates multiple cellular responses. Enavatuzumab induces tumor growth inhibition through direct TweakR signaling and antibody dependent cell-mediated cytotoxicity (ADCC). Enavatuzumab can actively recruits and activates myeloid effectors to kill tumor cells. Enavatuzumab inhibits the growth of various human TweakR-positive cancer cell lines and xenografts in vitro and in vivo .

HY-P991453

Anti-CD371/CLEC12A Antibody (H6e7)	C-type Lectin-like Receptors (CTLRs)	Cancer
Anti-CD371/CLEC12A Antibody (H6e7) is a human monoclonal antibody (mAb) targeting *CD371/CLEC12A*. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) .

Species:	Human (31) Rhesus Macaque (2) Rat (2) Mouse (8) Cynomolgus (2)
Tag:	GFP (1) His (32) Strep (3) Tag Free (6) Avi (6) MBP (2) Flag (6) Fc (10)
Source:	HEK293 (37) CHO (1) E. coli (8)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P71909

	TNFRSF12A Protein, Human CD 266; CD266; CD266 antigen; FGF inducible 14; FGF-inducible 14; Fibroblast growth factor inducible immediate early response protein 14; Fibroblast growth factor-inducible immediate-early response protein 14; FN 14; FN14; TNFRSF 12a; TNFRSF12a; TNR12_HUMAN; Tumor necrosis factor receptor superfamily member 12a; TWEAK R; Tweak receptor; Tweak-receptor; TweakR	Human	E. coli
	TNFRSF12A Protein, the receptor for TNFSF12/TWEAK, acts as a weak apoptosis inducer in specific cell types. It also promotes angiogenesis, endothelial cell proliferation, and may modulate cellular adhesion to matrix proteins. Association with TRAF1, TRAF2, and potentially TRAF3 underscores its involvement in diverse cellular signaling pathways. TNFRSF12A Protein, Human is the recombinant human-derived TNFRSF12A protein, expressed by E. coli , with tag free.

HY-P704105

	MYL12A Protein, Human (His) Myosin regulatory light chain 12a; MYL12a; MLCB; MRLC3; RLC; Epididymis secretory protein Li 24 (HEL-S-24); MLC-2B; Myosin RLC; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain MRLC3	Human	E. coli
	MYL12A Protein, Human (His) is the recombinant human-derived MYL12A protein, expressed by E. coli, with C-6*His tag.

HY-P703443

	*dps Protein, Listeria monocytogenes serovar 1/2a* (His)** flp; fri	Others	E. coli
	dps Protein, Listeria monocytogenes serovar 1/2a (His) is the recombinant dps protein, expressed by E. coli, with His tag.

HY-P705440

	Zc3h12a Protein, Mouse (His) Endoribonuclease ZC3H12a; Monocyte chemotactic protein-induced protein 1; Zc3h12a; Mcpip; Mcpip1	Mouse	E. coli

HY-P706002

	Zc3h12a Protein, Human (His) Endoribonuclease ZC3H12a; Monocyte chemotactic protein-induced protein 1; Zc3h12a; Mcpip; Mcpip1	Human	E. coli

HY-P78623

	CLEC12A/MICL Protein, Rat (HEK293, His) CLEC12a; MICL; CLL-1; CLL1; DCAL2; DCAL-2; CD371	Rat	HEK293
	CLEC12A/MICL (C-type lectin domain family 12 member A/myelosuppressive C-type lectin-like receptor) is a cell surface receptor that acts as a modulator of signaling cascades, specifically promoting target MAP kinases Protease. CLEC12A/MICL Protein, Rat (HEK293, His) is the recombinant rat-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag. The total length of CLEC12A/MICL Protein, Rat (HEK293, His) is 205 a.a., with molecular weight of 32-45 kDa.

HY-P77401

	IL-12 alpha Protein, Rhesus Macaque (HEK293, Fc) Interleukin-12 subunit alpha; IL-12a; CLMF p35; IL-12 subunit p35; IL12a	Rhesus Macaque	HEK293
	Interleukin-12 subunit alpha (IL-12A; IL-12p35), an immune-suppressive cytokine, encodes a subunit of the cytokine IL-12 that acts on T and natural killer cells, and has a broad array of biological activities. IL-12A heterodimerizes with IL-12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 alpha Protein, Rhesus Macaque (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag . It consists of IL-12A (M1-S219).

HY-P703286

	SLC12A7/KCC4 Protein, Human (HEK293) KCC4	Human	HEK293
	SLC12A7/KCC4 Protein, Human (HEK293) is the recombinant human-derived KCC4, expressed by HEK293 , with tag Free labeled tag. ,

HY-P72434

	TNFRSF12A Protein, Human (HEK293, Fc) 1 Publications Verification TNFRSF12a; Fibroblast growth factor-inducible immediate-early response protein 14; FN14; CD266 antigen and tweak-receptor	Human	HEK293
	TNFRSF12A Protein, the receptor for TNFSF12/TWEAK, acts as a weak apoptosis inducer in specific cell types. It also promotes angiogenesis, endothelial cell proliferation, and may modulate cellular adhesion to matrix proteins. Association with TRAF1, TRAF2, and potentially TRAF3 underscores its involvement in diverse cellular signaling pathways. TNFRSF12A Protein, Human (HEK293, Fc) is the recombinant human-derived TNFRSF12A protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P72435

	TNFRSF12A Protein, Mouse (HEK293, Fc) TNFRSF12a; Fibroblast growth factor-inducible immediate-early response protein 14; FN14; CD266 antigen and tweak-receptor	Mouse	HEK293
	TNFRSF12A Protein, a receptor for TNFSF12/TWEAK, exhibits a weak apoptosis-inducing ability in specific cells.It promotes angiogenesis and endothelial cell proliferation, and may modulate cellular adhesion to matrix proteins.In functional interactions, TNFRSF12A associates with TRAF1 and TRAF2, possibly with TRAF3, suggesting its involvement in signaling pathways contributing to diverse cellular processes.TNFRSF12A Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived TNFRSF12A protein, expressed by HEK293 , with C-hFc labeled tag.

HY-P703215

	SLC12A3 Protein, Human (HEK293, His, MBP, Flag) NCC; TSC	Human	HEK293
	SLC12A3 Protein, Human (HEK293, His, MBP, Flag) is the recombinant human-derived SLC12A3, expressed by HEK293 , with His, MBP, Flag labeled tag. ,

HY-P7370

	IL-12 Protein, Rat (CHO) rRtIL-12; CLMF; IL-12a; IL-12B	Rat	CHO
	IL-12 Protein, Rat (CHO) is an inflammatory cytokine that promotes the response of the immune system.

HY-P703287

	SLC12A7/KCC4 Protein, Human (HEK293, Strep, His) KCC4	Human	HEK293
	SLC12A7/KCC4 Protein, Human (HEK293, Strep, His) is the recombinant human-derived KCC4, expressed by HEK293 , with Strep, His labeled tag. ,

HY-P703288

	SLC12A7/KCC4 Protein, Human (HEK293, His, MBP, Flag) KCC4	Human	HEK293
	SLC12A7/KCC4 Protein, Human (HEK293, His, MBP, Flag) is the recombinant human-derived SLC12A7, expressed by HEK293 , with His, MBP, Flag labeled tag. ,

HY-P77631

	CLEC12A/MICL Protein, Human (HEK293, Fc) MICL; CLL-1; CLEC12a; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2	Human	HEK293
	CLEC12A/MICL (C-type lectin domain family 12 member A/myelosuppressive C-type lectin-like receptor) is a cell surface receptor that acts as a modulator of signaling cascades, specifically promoting target MAP kinases Protease. CLEC12A/MICL Protein, Human (HEK293, Fc) is the recombinant human-derived CLEC12A/MICL protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P77903

	CLEC12A/MICL Protein, Cynomolgus (HEK293, His) MICL; CLL-1; CLEC12a; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2	Cynomolgus	HEK293
	CLEC12A/MICL Protein is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. CLEC12A is a cell surface receptor known to regulate signaling cascades and facilitate the tyrosine phosphorylation of target MAP kinases. It interacts with PTPN6 and PTPN11, indicating its involvement in intricate cellular signaling processes. CLEC12A/MICL Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag.

HY-P77905

	CLEC12A/MICL Protein, Mouse (HEK293, His) MICL; CLL-1; CLEC12a; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2	Mouse	HEK293
	CLEC12A/MICL protein acts as a cell surface receptor, facilitating tyrosine phosphorylation of MAP kinases and modulating signaling cascades. It interacts with PTPN6 and PTPN11, key proteins in signaling pathways. CLEC12A/MICL Protein, Mouse (HEK293, His) is the recombinant mouse-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag.

HY-P77633

	CLEC12A/MICL Protein, Human (Biotinylated, HEK293, His-Avi) MICL; CLL-1; CLEC12a; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2	Human	HEK293
	CLEC12A/MICL (C-type lectin domain family 12 member A/myelosuppressive C-type lectin-like receptor) is a cell surface receptor that acts as a modulator of signaling cascades, specifically promoting target MAP kinases Protease. CLEC12A/MICL Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived CLEC12A/MICL protein, expressed by HEK293 , with C-Avi, N-His labeled tag.

HY-P77634

	CLEC12A/MICL Protein, Human (Biotinylated, HEK293, Fc-Avi) MICL; CLL-1; CLEC12a; CLL1; DCAL2; DCAL-2; CD371; CD303; CLECSF11; CLECSF7; DLEC; HECL; PRO34150; DCAL-2	Human	HEK293
	CLEC12A/MICL (C-type lectin domain family 12 member A/myelosuppressive C-type lectin-like receptor) is a cell surface receptor that acts as a modulator of signaling cascades, specifically promoting target MAP kinases Protease. CLEC12A/MICL Protein, Human (Biotinylated, HEK293, Fc-Avi) is the recombinant human-derived CLEC12A/MICL protein, expressed by HEK293 , with N-hFc, N-Avi labeled tag.

HY-P702022

	SLC12A2 Protein, Human (HEK293, His, StrepⅡ, FLAG) SLC12a2; Solute carrier family 12 member 2; Basolateral Na-K-Cl symporter; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2	Human	HEK293
	SLC12A2 Protein mediates electroneutral transport of chloride, potassium, and/or sodium ions across the membrane, crucial for regulating ionic balance and cell volume. SLC12A2 Protein, Human (HEK293, His, Strep, FLAG) is the recombinant human-derived SLC12A2 protein, expressed by HEK293 insect cells , with N-Strep, C-Flag, N-8*His labeled tag.

HY-P703077

	SLC12A2 Protein, Human (HEK293, His, StrepⅡ, GFP) SLC12a2; Solute carrier family 12 member 2; Basolateral Na-K-Cl symporter; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2	Human	HEK293
	SLC12A2 Protein mediates electroneutral transport of chloride, potassium, and/or sodium ions across the membrane, crucial for regulating ionic balance and cell volume. SLC12A2 Protein, Human (HEK293, His, Strep, GFP) is the recombinant human-derived SLC12A2 protein, expressed by HEK293 , with N-Strep, N-EGF, N-His labeled tag.

HY-P701008

	IL-12 Protein, Cynomolgus (HEK293, His) CLMF; CLMF2; IL-12a; IL-12B; IL12; IL12 p70; IMD28; IMD29; NFSK; NKSF1; NKSF2; P35; IL-12 subunit p35; IL12a; interleukin 12	Cynomolgus	HEK293
	IL-12 Protein, forming a heterodimer with IL23A, generates the cytokine IL-23, pivotal in innate and adaptive immunity. Collaborating with IL-17, IL-23 prompts an acute response to infection in peripheral tissues. Binding to the receptor complex IL12RB1 and IL23R, IL-23 activates Jak-Stat signaling, preferentially stimulates memory T-cells, and induces pro-inflammatory cytokine production. Implicated in autoimmune inflammation and tumorigenesis, IL-23 acts as a growth factor for activated T and NK cells, enhances NK cell lytic activity, and stimulates IFN-gamma production by resting PBMC. IL-12 Protein, Cynomolgus (HEK293, His) is a recombinant protein dimer complex containing cynomolgus-derived IL-12 protein, expressed by HEK293, with C-His labeled tag. IL-12 Protein, Cynomolgus (HEK293, His), has molecular weight of 45-48 kDa (IL-12B) & 38-44 kDa (IL-12A), respectively.

HY-P77702

	IL-12 Protein, Human (Biotinylated, HEK293, His-Avi) CLMF; CLMF2; IL-12a; IL-12B; IL12; IL12 p70; IMD28; IMD29; NFSK; NKSF1; NKSF2; P35; IL-12 subunit p35; IL12a; interleukin 12	Human	HEK293
	IL-35 protein plays a key role in immune regulation, forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B. IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production. IL-12 Protein, Human (Biotinylated, HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived IL-12 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. IL-12 Protein, Human (Biotinylated, HEK293, His-Avi), has molecular weight of ~40-45 kDa.

HY-P73880

	IL-35 Protein, Human (HEK293, Flag-His) CLMF; IL-12a; IL-35; Interleukin-35; NFSK; NKSF1; P35	Human	HEK293
	IL-35 protein plays a key role in immune regulation, forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B. IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production. IL-35 Protein, Human (HEK293, Flag-His) is a recombinant protein dimer complex containing human-derived IL-35 protein, expressed by HEK293 , with C-His, C-Flag labeled tag. IL-35 Protein, Human (HEK293, Flag-His), has molecular weight of ~48.3 kDa.

HY-P705112

	IL-12 Protein, Human (Biotinylated, HEK293, His-Avi, Flag) CLMF; CLMF2; IL-12a; IL-12B; IL12; IL12 p70; IMD28; IMD29; NFSK; NKSF1; NKSF2; P35; IL-12 subunit p35; IL12a; interleukin 12	Human	HEK293

HY-P73882

	IL-35 Protein, Human (HEK293, His, hFc-Flag) CLMF; IL-12a; IL-35; Interleukin-35; NFSK; NKSF1; P35	Human	HEK293
	IL-35 protein plays a key role in immune regulation, forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B. IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production. IL-35 Protein, Human (HEK293, His, hFc-Flag) is a recombinant protein dimer complex containing human-derived IL-35 protein, expressed by HEK293 , with C-hFc, C-Flag, C-8*His labeled tag.

HY-P73898

	IL-12 Protein, Human (HEK293, His) Interleukin-12 subunit alpha; IL-12a; CLMF p35; IL-12 subunit p35; NKSF1	Human	HEK293
	Interleukin-12 subunit alpha (IL-12A; IL-12p35), an immune-suppressive cytokine, encodes a subunit of the cytokine IL-12 that acts on T and natural killer cells, and has a broad array of biological activities. IL-12A heterodimerizes with IL-12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 Protein, Human (547a.a, HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag . It consists of IL-12A (M1-S219) and IL-12B (M1-S328).

HY-P704749

	Kras4B Protein, Human (G12A, His) rHuGTPase Kras4B, His; Ki-Ras; c-K-ras; KRAS2; RASK2; CFC2	Human	E. coli
	The Kras4B protein interacts specifically with GPR31, dependent on farnesylation. This binding suggests a regulatory role for Kras4B in association with GPR31, emphasizing the importance of the farnesylation process. Comprehensive exploration into the molecular details of this interaction is crucial to understand the precise mechanisms and functional implications in cellular processes or signaling pathways. Kras4B Protein, Human (G12A, His) is the recombinant human-derived Kras4B protein, expressed by E. coli, with N-His labeled tag.

HY-P76267

	CLEC12A/MICL Protein, Human (HEK293, His) C-type lectin domain family 12 member A; CLL-1; DCAL-2; MICL; CD371	Human	HEK293
	CLEC12A/MICL (C-type lectin domain family 12 member A/myelosuppressive C-type lectin-like receptor) is a cell surface receptor that acts as a modulator of signaling cascades, specifically promoting target MAP kinases Protease. CLEC12A/MICL Protein, Human (HEK293, His) is the recombinant human-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag.

HY-P700099AF

	Animal-Free IL-12 alpha Protein, Human (His) Interleukin-12 subunit alpha; IL-12 subunit p35; IL-12a; Cytotoxic Lymphocyte Maturation Factor 35 kDa	Human	E. coli
	IL-35 protein plays a key role in immune regulation, forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B. IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production. Animal-Free IL-12 alpha Protein, Human (His) is the recombinant human-derived animal-FreeIL-12 alpha protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P700190AF

	Animal-Free IL-12 alpha Protein, Mouse (His) Interleukin-12 subunit alpha; IL-12 subunit p35; IL-12a; Cytotoxic Lymphocyte Maturation Factor 35 kDa	Mouse	E. coli
	IL-12 alpha protein forms two cytokines: IL-12 and IL-35. It modulates T cell and natural killer cell responses, induces IFN-γ production, and promotes Th1 cell differentiation. Animal-Free IL-12 alpha Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-12 alpha protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.

HY-P704381

	IL-12 alpha Protein, Human (HEK293, hFc) Interleukin-12 subunit alpha; IL-12 subunit p35; IL-12a; Cytotoxic Lymphocyte Maturation Factor 35 kDa	Human	HEK293
	IL-35 protein plays a key role in immune regulation, forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B. IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production. IL-12 alpha Protein, Human (HEK293, hFc) is the recombinant human-derived IL-12 alpha protein, expressed by HEK293, with C-hFc labeled tag.

HY-P78653

	FITC-Labeled CLEC12A/MICL Protein, Human (HEK293, His, solution) C-type lectin domain family 12 member A; CLL-1; DCAL-2; MICL; CD371	Human	HEK293
	CLEC12A/MICL (C-type lectin domain family 12 member A/myelosuppressive C-type lectin-like receptor) is a cell surface receptor that acts as a modulator of signaling cascades, specifically promoting target MAP kinases Protease. FITC-Labeled CLEC12A/MICL Protein, Human (HEK293, His, solution) is the recombinant human-derived CLEC12A/MICL protein, expressed by HEK293 , with N-His labeled tag.

HY-P7032

	IL-12 Protein, Human (HEK293) 3 Publications Verification IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Human	HEK293
	IL-12 Protein, Human (HEK293) is a HEK293 cell derived heterodimeric, pro-inflammatory cytokine.

HY-P70666

	IL-12 Protein, Mouse (HEK293) 1 Publications Verification IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40;	Mouse	HEK293
	IL-12 protein is a immune-suppressive heterodimeric cytokine, composed by IL-12A subunit (IL-12p35) and IL-12B subunit (IL-12p40), is naturally produced by dendritic cells. IL-12 exerts functions to activate and link the innate and acquired immune responses. IL-12 Protein, Mouse is produced in HEK293 cells, with tag free.

HY-P7032G

	GMP IL-12 Protein, Human (HEK293) IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Human	HEK293
	Interleukin-12 subunit alpha (IL-12A; IL-12p35), an immune-suppressive cytokine, encodes a subunit of the cytokine IL-12 that acts on T and natural killer cells, and has a broad array of biological activities. IL-12A heterodimerizes with IL-12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. GMP IL-12 Protein, Human (HEK293), a recombinant GMP-grade protein, is produced in HEK293 cells. It consists of IL-12A and IL-12B.

HY-P73156

	GMP IL-12 Protein, Human (HEK293, His) GMP IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Human	HEK293
	Interleukin-12 subunit alpha (IL-12A; IL-12p35), an immune-suppressive cytokine, encodes a subunit of the cytokine IL-12 that acts on T and natural killer cells, and has a broad array of biological activities. IL-12A heterodimerizes with IL-12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 Protein, Human (HEK293, His), a recombinant GMP-grade protein, is produced in HEK293 cells with a C-Terminal His-tag . It consists of IL-12A (M1-S219) and IL-12B (M1-S328).

HY-P73159

	IL-12 Protein, Mouse (HEK293, His) IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Mouse	HEK293
	Interleukin-12 subunit alpha (IL-12A; IL-12p35), an immune-suppressive cytokine, encodes a subunit of the cytokine IL-12 that acts on T and natural killer cells, and has a broad array of biological activities. IL-12A heterodimerizes with IL-12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 Protein, Mouse (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag. It consists of IL-12A (M1-A215) and IL-12B (M1-S335).

HY-P73160

	IL-12 beta Protein, Human (HEK293, Fc) IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Human	HEK293
	IL-12 beta Protein, also known as natural killer cell stimulatory factor 2, is a common subunit (p40) of IL-12 and IL-23. IL-12 is a inflammatory factor expressed by activated macrophages, and involves in Th1-type immune response against cancer. IL-12 beta Protein located outside the cell membrane, involves in singalling mediated by Jak-STAT. IL-12 beta Protein consists of 328 amino acids (M1-S328) with a fibronectin type-III domain (237-328 a.a). IL-12 beta Protein, Human (M1-S328) is produced in HEK293 cells with a C-Terminal Fc-tag.

HY-P73897

	IL-12 Protein, Rhesus Macaque (HEK293, His) IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Rhesus Macaque	HEK293
	Interleukin-12 subunit alpha (IL-12A; IL-12p35), an immune-suppressive cytokine, encodes a subunit of the cytokine IL-12 that acts on T and natural killer cells, and has a broad array of biological activities. IL-12A heterodimerizes with IL-12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 Protein, Rhesus Macaque (HEK293, His) is produced in HEK293 cells with a C-Terminal His-tag . It consists of IL-12A (M1-S219) and IL-12B (M1-S328).

HY-P700101AF

	Animal-Free IL-12 Protein, Human (HEK293, His) Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Human	HEK293
	IL-35 protein plays a key role in immune regulation, forming IL-12 cytokine with IL12B or IL-35 cytokine with EBI3/IL27B. IL-12 modulates T cell and natural killer cell responses and induces interferon gamma production. Animal-Free IL-12 Protein, Human (HEK293, His) is a recombinant protein dimer complex containing human-derived animal-FreeIL-12 protein, expressed by HEK293 , with C-His labeled tag. Animal-Free IL-12 Protein, Human (HEK293, His), has molecular weight of ~59.55 kDa.This product is for cell culture use only.

HY-P73157

	IL-12 Protein, Mouse (HEK293, Fc) IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Mouse	HEK293
	Interleukin-12 subunit alpha (IL-12A; IL-12p35), an immune-suppressive cytokine, encodes a subunit of the cytokine IL-12 that acts on T and natural killer cells, and has a broad array of biological activities. IL-12A heterodimerizes with IL-12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 Protein, Mouse (HEK293, Fc) is produced in HEK293 cells with a C-Terminal Fc-tag. It consists of IL-12A (M1-A215) and IL-12B (M1-S335).

HY-P73158

	IL-12 Protein, Mouse (HEK293, His-Fc) IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Mouse	HEK293
	Interleukin-12 subunit alpha (IL-12A; IL-12p35), an immune-suppressive cytokine, encodes a subunit of the cytokine IL-12 that acts on T and natural killer cells, and has a broad array of biological activities. IL-12A heterodimerizes with IL-12B to form the IL-12 cytokine or with EBI3/IL27B to form the IL-35 cytokine. IL-12 Protein, Mouse (HEK293, His-Fc) is produced in HEK293 cells with a C-Terminal His-tag and a C-Terminal Fc-tag. It consists of IL-12A (M1-A215) and IL-12B (M1-S335).

HY-P77511

	IL-12 Protein, Human (Biotinylated, HEK293, His) IL-12; Interleukin 12; Interleukin-12 subunit alpha; IL-12a; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35; Interleukin-12 subunit beta; IL-12B; Cytotoxic lymphocyte maturation factor 40 kDa subunit; CLMF p40; IL-12 subunit p40	Human	HEK293
	IL-12 beta Protein, also known as natural killer cell stimulatory factor 2, is a common subunit (p40) of IL-12 and IL-23. IL-12 is a inflammatory factor expressed by activated macrophages, and involves in Th1-type immune response against cancer. IL-12 beta Protein located outside the cell membrane, involves in singalling mediated by Jak-STAT. IL-12 beta Protein consists of 328 amino acids (M1-S328) with a fibronectin type-III domain (237-328 a.a). IL-12 beta Protein, Human (M1-S219) is a biotinylated protein, produced in HEK293 cells with a C-Terminal His-tag.

HY-P700919

	*HLA-A11:01&B2M&KRAS G12A(VVVGAAGVGK) Monomer Protein, Human (Biotinylated, HEK293, His-Avi)** MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD	Human	HEK293

HY-P700920

	*HLA-A11:01&B2M&KRAS G12A(VVVGAAGVGK) Monomer Protein, Human (HEK293, His-Avi)** MHC; KRAS; K-Ras 2; KRAS2; C-K-RAS; CFC2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; KRAS1; KRAS2; NS; NS3; RASK2; GTPase Kras; KI-RAS; RALD	Human	HEK293

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Host:	Mouse (7) Rabbit (16)
Reactivity:	Human (20) Rat (12) Mouse (12) human (1)
Application:	IHC-P (12) ICC/IF (9) IF-Tissue (1) IP (5) IHC-F (1) WB (18) FC (8) ELISA (8)
Isotype:	IgG,Kappa (1) IgG (14) IgG1 (4) IgG2a (2) IgG/Kappa (1)
Conjugation:	Non-conjugated (23) Biotin (6)
Clonality:	Monoclonal (15) Recombinant (10)
Modification:	Unmodified (16)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P83202

	HspA12A Antibody (YA2947) FLJ13874 antibody; Heat shock 70 kDa protein 12a antibody; heat shock 70kD protein 12a antibody; heat shock 70kDa protein 12a antibody; HS12a_HUMAN antibody; Hspa12a antibody; KIAA0417 antibody	WB, IHC-P, ICC/IF, IP	Human, Mouse, Rat
	HspA12A Antibody (YA2947) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to HspA12A.

HY-P810450

	TNFSF12 Antibody (YA9755) FN14, TNFRSF 12a, Tweak receptor, TweakR,	WB, IHC-P, ICC/IF, IF-Tissue, IP	Human, Mouse, Rat
	TNFSF12 Antibody (YA9755) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to TNFSF12.

HY-P82931

	CD266 Antibody (YA2676) CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12a; Tweak receptor; TweakR	WB, IHC-P, IP	Human, Mouse, Rat
	CD266 Antibody (YA2676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD266.

HY-P86347

	MYPT1 Antibody (YA6039) PPP1R12a; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12a; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit	WB, IHC-P, ICC/IF, ELISA	Human
	MYPT1 Antibody (YA6039) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to MYPT1.

HY-P82931A

	CD266 Antibody (YA2676)(PBS only) CD266 antigen; FGF inducible 14; Fibroblast growth factor inducible immediate early response protein 14; FN14; TNFRSF 12a; Tweak receptor; TweakR	WB, IHC-P, IP	Human, Mouse, Rat
	CD266 Antibody (YA2676) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CD266.

HY-P810682

	Phospho-MYPT1 (Thr853) Antibody (YA9940) PPP1R12a; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12a; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit	WB	Human, Mouse, Rat
	Phospho-MYPT1 (Thr853) Antibody (YA9940) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-MYPT1 (Thr853).

HY-P810683

	Phospho-MYPT1 (Thr696) Antibody (YA9941) PPP1R12a; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12a; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit	WB	Human, Mouse, Rat
	Phospho-MYPT1 (Thr696) Antibody (YA9941) is a Rabbit-derived and non-conjugated IgG Recombinant, Monoclonal antibody, targeting to Phospho-MYPT1 (Thr696).

HY-P84631

	CLEC12A Antibody (YA4328) CLEC12a; MICL; CD371; CLL-1; DCAL-2	WB, ICC/IF, FC, ELISA	Human
	CLEC12A Antibody (YA4328) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CLEC12A.

HY-P87667

	HSPA12A Antibody (YA7352)	WB, IHC-P, ICC/IF, ELISA	Human, Mouse, Rat
	HSPA12A Antibody (YA7352) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to HSPA12A.

HY-P84631A

	CLEC12A Antibody (YA4328)(PBS only) CLEC12a; MICL; CD371; CLL-1; DCAL-2	WB, ICC/IF, FC, ELISA	Human
	CLEC12A Antibody (YA4328) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CLEC12A.

HY-P81674

	CLEC12A Antibody (YA1419) CLEC12a; MICL; CLL-1; CLL1; DCAL2; DCAL-2; CD371	FC, ELISA	Human
	CLEC12A Antibody (YA1419) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CLEC12A.

HY-P89792

	*IL-12A* p35/p70 Antibody (YA9136)**	FC	human
	IL-12A p35/p70 Antibody (YA9136) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to IL-12A p35/p70.

HY-P81658

	SLC12A1 Antibody (YA1403) BSC1; NKCC2	WB	Human
	SLC12A1 Antibody (YA1403) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLC12A1.

HY-P81658A

	SLC12A1 Antibody (YA1403)(PBS only) BSC1; NKCC2	WB	Human
	SLC12A1 Antibody (YA1403) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLC12A1.

HY-P81733

	ORP150 Antibody (YA1478) Grp170; HSP12a; Hyou1; Orp150	WB, IHC-P	Human, Mouse, Rat
	ORP150 Antibody (YA1478) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ORP150.

HY-P84775

	PLA2G12A Antibody (YA4472) GXII; ROSSY; PLA2G12	IHC-P, FC, ELISA	Human
	PLA2G12A Antibody (YA4472) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLA2G12A.

HY-P81733A

	ORP150 Antibody (YA1478)(PBS only) Grp170; HSP12a; Hyou1; Orp150	WB, IHC-P	Human, Mouse, Rat
	ORP150 Antibody (YA1478) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ORP150.

HY-P84775A

	PLA2G12A Antibody (YA4472)(PBS only) GXII; ROSSY; PLA2G12	IHC-P, FC, ELISA	Human
	PLA2G12A Antibody (YA4472) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to PLA2G12A.

HY-P83143

	PEX19 Antibody (YA2888) HK33; PBD12a; Peroxin 19; PEX19; PMP1; PMPI; PXF; PXMP1	WB, ICC/IF, FC, IP	Human, Rat
	PEX19 Antibody (YA2888) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PEX19.

HY-P83742

	SLC12A1 Antibody (YA3471) BSC1 antibody; Bumetanide sensitive sodium 3 antibody; Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 antibody; Kidney specific Na K Cl symporter antibody; Kidney-specific Na-K-Cl symporter antibody; MGC48843 antibody; Na K 2Cl cotransporter antibody; NKCC2 antibody; potassiumchloride cotransporter 2 antibody; S12a1_HUMAN antibody; Slc12a1 antibody; sodium potassium chloride cotransporter 2 antibody; solute carrier family 12 (sodium/potassium/chloride transporters) antibody; Solute carrier family 12 member 1 antibody	WB, IHC-P, ICC/IF	Human, Mouse, Rat
	SLC12A1 Antibody (YA3471) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to SLC12A1.

HY-P84992

	CLEC12A Antibody (YA4684) CLL1; MICL; CLL-1; DCAL-2; C-type lectin domain family 12 member A; CD371; CD371 nanobody;	ELISA	Human
	CLEC12A Antibody (YA4684) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to CLEC12A.

HY-P87092

	Slc12a5/KCC2 Antibody (YA6785) Electroneutral potassium chloride cotransporter 2 antibody; Electroneutral potassium-chloride cotransporter 2 antibody; Erythroid K Cl cotransporter 2 antibody; Furosemide sensitive K Cl cotransporter antibody; hKCC2 antibody; K-Cl cotransporter 2 antibody; KCC 2 antibody; KCC2 antibody; KIAA1176 antibody; Neuronal K Cl cotransporter antibody; Electroneutral potassium chloride cotransporter 2 antibody; Electroneutral potassium-chloride cotransporter 2 antibody; Erythroid K Cl cotransporter 2 antibody; Furosemide sensitive K Cl cotransporter antibody; hKCC2 antibody; K-Cl cotransporter 2 antibody; KCC 2 antibody; KCC2 antibody; KIAA1176 antibody; Neuronal K Cl cotransporter antibody; Neuronal K-Cl cotransporter antibody; Potassium Chloride Cotransporter antibody; Potassium chloride transporter 5 antibody; rKCC2 antibody; S12a5 antibody; S12a5_HUMAN antibody; SLC12a5 antibody; Solute carrier family 12 (potassium chloride transporter) member 5 antibody; Solute carrier family 12 member 5 antibody;	IHC-F, WB	Mouse, Rat
	Slc12a5/KCC2 Antibody (YA6785) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to Slc12a5/KCC2.

HY-P87164

	p21 Antibody (YA6857) CAP20 antibody; CDK-interacting protein 1 antibody; CDKI antibody; CDKN1 antibody; Cdkn1a antibody; CDN1A_HUMAN antibody; CIP1 antibody; Cyclin Dependent Kinase Inhibitor 1A antibody; Cyclin-dependent kinase inhibitor 1 antibody; Cyclin-dependent kinase inhibitor 1A (P21) antibody; CAP20 antibody; CDK-interacting protein 1 antibody; CDKI antibody; CDKN1 antibody; Cdkn1a antibody; CDN1A_HUMAN antibody; CIP1 antibody; Cyclin Dependent Kinase Inhibitor 1A antibody; Cyclin-dependent kinase inhibitor 1 antibody; Cyclin-dependent kinase inhibitor 1A (P21) antibody; Cyclin-dependent kinase inhibitor 1A (p21, Cip1) antibody; DNA Synthesis Inhibitor antibody; MDA-6 antibody; MDA6 antibody; Melanoma differentiation-associated protein 6 antibody; Melanoma differentiation-associated protein antibody; p21 antibody; P21 protein antibody; p21CIP1 antibody; p21Cip1/Waf1 antibody; p21WAF antibody; PIC1 antibody; SDI1 antibody; SLC12a9 antibody; WAF1 antibody; Wild type p53 activated fragment 1 (WAF1) antibody; Wild type p53 activated fragment 1 antibody; Wildtype p53-activated fragment 1 antibody;	WB, ICC/IF, IHC-P, FC	Mouse
	p21 Antibody (YA6857) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to p21.