TNFSF12 Antibody (YA9755)
(Synonyms: FN14, TNFRSF 12A, Tweak receptor, TweakR,)TNFSF12 Antibody (YA9755) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to TNFSF12.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF, IF-Tissue, IP
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4) , 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IP
IP: Immunoprecipitation
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|---|---|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 | 1:50-200 | 1:20-50 |
Product Details
TNFSF12 Antibody (YA9755) is a Rabbit-derived and non-conjugated IgG Monoclonal antibody, targeting to TNFSF12.
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Host Rabbit
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Clonality Monoclonal
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Species ReactivityHuman, Mouse, Rat
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Calculated Molecular Weight Predicted band size: 13.9 kDa;
Recombinant protein of human TNFSF12.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4) , 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
TNFSF12 is a Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins
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Subcellular Localization
Membrane
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Expression
Tissue_Specificity: Highly expressed in heart, placenta and kidney. Intermediate expression in lung, skeletal muscle and pancreas.
Induction: By FGF1 and phorbol ester. -
Isoforms & Post-Translational Modification
TNFSF12 has 2 isoforms, Q9NP84-1: amino acid length is 129, molecular weight is 13911 Da (predicted); Q9NP84-2: amino acid length is 94, molecular weight is 10191 Da (predicted).
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Subunit
Associates with TRAF1 and TRAF2, and probably also with TRAF3
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SwissProt ID
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Synonyms
FN14, TNFRSF 12A, Tweak receptor, TweakR,
Documentation