MAO-B-IN-13
MAO-B-IN-13 (compound 12a) is a highly potent, reversible and blood-brain barrier (BBB) penetrant MAO-B inhibitor with an IC50 value of 10 nM. MAO-B-IN-13 has neuroprotective and antioxidant activity. MAO-B-IN-13 can be used for researching Parkinson’s disease.
For research use only. We do not sell to patients.
- CAS No.: 2105918-34-9
- Formula: C18H19NO3
- Molecular Weight:297.35
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
MAO-B 10 nM (IC50) |
In Vitro
MAO-B-IN-13 (compound 12a) (1 μM, 10 μM and 50 μM; 48 hours) has neuroprotective effect on H2O2-induced PC-12 cell injury[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2105918-34-9
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Molecular Weight 297.35
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Formula C18H19NO3
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SMILES
OC1=CC=C(/C=C/C2=CN=C(C)C3=C2COC(C)(C)O3)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MAO-B-IN-13 Related Classifications
HY-147953 Related Classifications
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