ORP150 Antibody (YA1478)(PBS only)

Cat. No.: HY-P81733A: Data Sheet User Guide for Antibodies
FAQs
Technical Support

ORP150 Antibody (YA1478) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ORP150.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

ORP150 Antibody (YA1478) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ORP150.

Host

Rabbit

Molecular Weight

Predicted band size: 111 kDa;

Observed band size: 150 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9Y4L1

Gene ID

10525 [NCBI]

Immunogen

A synthetic peptide of human ORP150

Application &
Dilution Ratio

Application	Dilution Ratio
WB WB: Western Blot	1:500-1:1000
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:50-1:100

Purity	Affinity Purified	Conjugation	Non-conjugated
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. Promotes HSPA5/BiP-mediated ATP nucleotide exchange and thereby activates the unfolded protein response (UPR) pathway in the presence of endoplasmic reticulum stress (By similarity). May play a role as a molecular chaperone and participate in protein folding

Subcellular Localization：Endoplasmic reticulum lumen

Expression：
Tissue_specificity:Highly expressed in tissues that contain well-developed endoplasmic reticulum and synthesize large amounts of secretory proteins. Highly expressed in liver and pancreas and lower expression in brain and kidney. Also expressed in macrophages within aortic atherosclerotic plaques, and in breast cancers

Induction:By hypoxia and also by 2-deoxyglucose or tunicamycin

Isoforms & Post-Translational Modification：Q9Y4L1 has 2 isomers: Q9Y4L1-1: 111335 Da (predicted); Q9Y4L1-2: 62757 Da (predicted).

Subunit：Part of a large chaperone multiprotein complex comprising DNAJB11, HSP90B1, HSPA5, HYOU, PDIA2, PDIA4, PDIA6, PPIB, SDF2L1, UGGT1 and very small amounts of ERP29, but not, or at very low levels, CALR nor CANX

Research Field

Cardiovascular

Synonyms

Grp170; HSP12A; Hyou1; Orp150

Documentation

User Guide for Antibodies (1077 KB)