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Cat. No.: HY-N9651

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12a-Hydroxydalpanol

12a-Hydroxydalpanol is a rotenoid cytotoxic agent found in Amorpha fruticosa. 12a-Hydroxydalpanol exerts cytotoxic effects by inhibiting tumor cell proliferation. 12a-Hydroxydalpanol is promising for research of cancers.

For research use only. We do not sell to patients.

CAS No.: 85042-77-9
Formula: C₂₃H₂₄O₈
Molecular Weight:428.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

12a-Hydroxydalpanol Chemical Structure

CAS No.: 85042-77-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
A549	ED₅₀	9.28 μg/mL Compound: 8	Cytotoxicity against human A549 cells Cytotoxicity against human A549 cells	[PMID: 8326318]
HCT-8	ED₅₀	0.56 μg/mL Compound: 8	Cytotoxicity against human HCT8 cells Cytotoxicity against human HCT8 cells	[PMID: 8326318]
KB	ED₅₀	3.67 μg/mL Compound: 8	Cytotoxicity against human KB cells Cytotoxicity against human KB cells	[PMID: 8326318]
P388	ED₅₀	0.59 μg/mL Compound: 8	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 8326318]
RPMI-7951	ED₅₀	0.73 μg/mL Compound: 8	Cytotoxicity against human RPMI7951 cells Cytotoxicity against human RPMI7951 cells	[PMID: 8326318]
TE-671	ED₅₀	0.12 μg/mL Compound: 8	Cytotoxicity against human TE671 cells Cytotoxicity against human TE671 cells	[PMID: 8326318]

Chemical Information

CAS No. 85042-77-9
Molecular Weight 428.43
Formula C₂₃H₂₄O₈
SMILES

O[C@@]1([C@](CO2)([H])OC3=C(C[C@@H]4C(C)(O)C)C(O4)=CC=C3C1=O)C(C2=C5)=CC(OC)=C5OC
Structure Classification
- Flavonoids
- Other Flavonoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Li L, et al. Antitumor agents, 138. Rotenoids and isoflavones as cytotoxic constitutents from Amorpha fruticosa. J Nat Prod. 1993 May;56(5):690-8. [Content Brief]

[2]. Terada H, et al. Structural elucidation and chemical conversion of amorphispironone, a novel spironone form Amorpha fruticosa, to rotenoids[J]. Chemical and pharmaceutical bulletin, 1993, 41(1): 187-190.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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