- Natural Products
- Plants
- Leguminosae ExtractCompositae Extract
- Amorpha fruticosaL.
Amorpha fruticosaL.
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Amorpha fruticosaL. (18)
- 1
- Formula: C19H20O6
- Molecular Weight: 344.36
Deoxyelephantopin, a natural bioactive sesquiterpene lactone from Elephantopus scaber, has shown promising anticancer effects against a broad spectrum of cancers. Deoxyelephantopin inhibits NF-κB, MAPK, PI3K/Akt, and β-catenin signaling.
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- Formula: C20H22O6
- Molecular Weight: 358.39
Scabertopin is a sesquiterpene lactone. Scabertopin has been found to be prominent anticancer constituents.
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- Formula: C26H32O4
- Molecular Weight: 408.53
Amorfrutin B is a highly potent natural peroxisome proliferation-activated receptor γ (PPARγ) agonist with oral activity with Ki values of 19 nM and EC50 values of 73 nM, respectively. Amorfrutin B has hypoglycemic and neuroprotective activities.
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- Formula: C20H22O6
- Molecular Weight: 358.39
Isoscabertopin is a sesquiterpene lactone isolated from Elephantopus scaber L and shows anti-tumor activities.
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- Formula: C19H20O6
- Molecular Weight: 344.36
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- Formula: C17H25N7O5
- Molecular Weight: 407.42
Feldamycin is an antibacterial agent. Feldamycin inhibits highly purified Escherichia coli RNA polymerase, semi-conservative DNA replication, and the integration of 34S DNA fragments into larger DNA, and causes the accumulation of a 34S DNA species during replication. Feldamycin inhibits melanin synthesis and leukemia cell growth, and possesses antibacterial activity. Feldamycin can be used in research related to bacterial infections, leukemia, and melanoma.
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- Formula: C34H40O16
- Molecular Weight: 704.68
Amorphin is a phosphorylase b with glycogen metabolism activity. Amorphin binds directly to alpha-actinin, with alpha-actinin mediating its binding to actin filaments. Amorphin can be used for the research of McArdle’s disease and breast cancer.
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- Formula: C26H26O12
- Molecular Weight: 530.48
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- Formula: C23H22O7
- Molecular Weight: 410.42
Amorphigenin is a trothotenone compound. Amorphigenin inhibits osteoclast differentiation by suppressing the expression of c-Fos and NFATc1 in activated T cells. Amorphigenin degrades melanosome proteins by activating the AMPK-dependent autophagy pathway, but not in dependence of the mTOR pathway. Amorphigenin significantly protects bone mass and reduces bone erosion in a mouse model of inflammatory bone loss. Amorphigenin can be used to study inflammatory bone diseases, postmenopausal osteoporosis, and skin pigmentation disorders.
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- Formula: C23H22O7
- Molecular Weight: 410.42
Amorphispironone (Compound 1) is a rotenoid that can be isolated the leaves of A. fruticosa. Amorphispironone exhibits remarkable inhibitory effects on EBV-EA activation induced by TPA. Amorphispironone exhibits potent anti-tumor-promotion activity on mouse skin tumor promotion in vivo.
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- Formula: C23H24O8
- Molecular Weight: 428.43
12a-Hydroxydalpanol is a rotenoid cytotoxic agent found in Amorpha fruticosa. 12a-Hydroxydalpanol exerts cytotoxic effects by inhibiting tumor cell proliferation. 12a-Hydroxydalpanol is promising for research of cancers.
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- Formula: C23H22O8
- Molecular Weight: 426.42
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- Formula: C15H24
- Molecular Weight: 204.35
α-Gurjunene is a sesquiterpene. α-Gurjunene can be extracted from the volatile oil of C. tamala leaves.
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- Formula: C21H24O4
- Molecular Weight: 340.41
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- Formula: C19H24O5
- Molecular Weight: 332.39
Naphtho[1,2-b]furan, 2-propenoic acid deriv. is a Sesquiterpenoids product that can be isolated from the herbs of Elephantopus scaber.
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- Formula: C26H26O12
- Molecular Weight: 530.48
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- Formula: C23H20O7
- Molecular Weight: 408.40
6a,12a-Dehydro-α-toxicarol is a natural product that can be isolated from Amorpha fruticosa.
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