1. Protein Tyrosine Kinase/RTK
    NF-κB
    Autophagy
  2. ROS
    NF-κB
    Autophagy
  3. Isodeoxyelephantopin

Isodeoxyelephantopin 

Cat. No.: HY-N2585
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Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer.

For research use only. We do not sell to patients.

Isodeoxyelephantopin Chemical Structure

Isodeoxyelephantopin Chemical Structure

CAS No. : 38927-54-7

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Description

Isodeoxyelephantopin is a sesquiterpene lactone isolated from Elephantopus scaber. Isodeoxyelephantopin induces ROS generation, suppresses NF-κB activation. Isodeoxyelephantopin also modulates LncRNA expression and exhibit activities against breast cancer[1][2].

In Vitro

Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop.

Molecular Weight

344.36

Formula

C₁₉H₂₀O₆

CAS No.

38927-54-7

SMILES

C=C(C)C(O[[email protected]@H](CC1=C2)[[email protected]]3([H])[[email protected]@](OC(C3=C)=O)([H])/C=C(C)/C[[email protected]]2([H])OC1=O)=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

IsodeoxyelephantopinROSNF-κBAutophagyNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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