80489-90-3
80489-90-3
Chemical Structure
Amorfrutin A
- CAS No.: 80489-90-3
- Formula:C21H24O4
- Molecular Weight:340.41
IUPAC Name: 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-phenethylbenzoic acid
InChIKey: CTNFTPUIYFUXBE-UHFFFAOYSA-N
SMILES: O=C(O)C1=C(CCC2=CC=CC=C2)C=C(OC)C(C/C=C(C)\C)=C1O
Biological Activity: Amorfrutin A is the inhibition of NF-κB activation, that inhibits TNF-α-induced IκBα degradation, p65 nuclear translocation, and DNA-binding activity. Amorfrutin A promotes TNF-α-induced apoptosis in HeLa cell through promotion of caspase-3 and PARP proteolysis[1].
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Amorfrutin A | Amorfrutin A is the inhibition of NF-κB activation, that inhibits TNF-α-induced IκBα degradation, p65 nuclear translocation, and DNA-binding activity. Amorfrutin A promotes TNF-α-induced apoptosis in HeLa cell through promotion of caspase-3 and PARP proteolysis. | |||||||||||||||||||||
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