JAK1-IN-14
JAK1-IN-14 (Compound 12a) is a potent and selective JAK1 inhibitor. JAK1-IN-14 inhibits JAK1 and JAK2 with an IC50 value of 12.6 nM and 135 nM. JAK1-IN-14 suppresses hepatic fibrosis levels and can be used for the research of liver fibrosis and inflammatory diseases.
For research use only. We do not sell to patients.
- Formula: C20H30N6O
- Molecular Weight:370.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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JAK1 12.6 nM (IC50) |
JAK2 135 nM (IC50) |
Chemical Information
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Molecular Weight 370.49
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Formula C20H30N6O
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SMILES
CN(C1CCN(CC(N2CCC(C)CC2)=O)CC1)C3=C4C(NC=C4)=NC=N3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)