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9(R)-HETE-d8

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55

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6

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34

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Isotope-Labeled Compounds

9

Antibodies

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-101415

    Ubiquinone Q9; CoQ9; Ubiquinone 9

    Apoptosis Endogenous Metabolite Cardiovascular Disease
    Coenzyme Q9 (Ubiquinone Q9), the major form of ubiquinone in rodents, is an amphipathic molecular component of the electron transport chain that functions as an endogenous antioxidant. Coenzyme Q9 attenuates the diabetes-induced decreases in antioxidant defense mechanisms. Coenzyme Q9 improves left ventricular performance and reduces myocardial infarct size and cardiomyocyte apoptosis .
    Coenzyme Q<em>9</em>
  • HY-12323
    ISX-9
    Maximum Cited Publications
    8 Publications Verification

    Isoxazole 9

    Calcium Channel Neurological Disease
    ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation. ISX-9 activates Ca 2+ influx through both voltage-gated Ca 2+ channels and NMDA receptors and increases neuroD expression. ISX-9 also induces cardiomyogenic differentiation of Notch-activated epicardium-derived cells (NECs) .
    ISX-<em>9</em>
  • HY-N11692

    9-Hydroxystearic acid; 9-HSA

    HDAC Cancer
    9-Hydroxyoctadecanoic acid (9-HSA) is an HDAC1 inhibitor that inhibits ∼66.4% HDAC1 enzymatic activity at 5 μM. 9-Hydroxyoctadecanoic acid shows anticancer activity .
    <em>9</em>-Hydroxyoctadecanoic acid
  • HY-15511
    Tyrphostin A9
    1 Publications Verification

    Tyrphostin 9; Malonoben

    VEGFR Influenza Virus PDGFR Infection Cancer
    Tyrphostin A9, a PDGFR inhibitor, is a potent inducer of mitochondrial fission. Tyrphostin A9 emerged as the most potent and selective of 51 tyrosine kinase inhibitors tested against the TNF-induced respiratory burst. Tyrphostin A9 has anti-influenza virus activities.
    Tyrphostin A<em>9</em>
  • HY-107787

    Prothanon; 9,9-Dioxopromethazine; 9,9-Dioxypromethazin

    Histamine Receptor Inflammation/Immunology
    Dioxopromethazine is an orally active antihistamine. Dioxopromethazine inhibits asthmatic symptoms .
    Dioxopromethazine
  • HY-12323G

    Isoxazole 9

    Calcium Channel Cardiovascular Disease Neurological Disease
    ISX-9 (Isoxazole 9) is a potent inducer of adult neural stem cell differentiation.
    ISX-9
  • HY-130001

    CDK Cancer
    CDK9-IN-9 (example 2) is a potent and selective CDK9 inhibitor with an IC50 of 1.8 nM. CDK9-IN-9 inhibits CDK2 with an IC50 of 155 nM. CDK9-IN-9 has anti-cancer activity .
    CDK<em>9</em>-IN-<em>9</em>
  • HY-15159

    Polo-like Kinase (PLK) Cancer
    Cyclapolin 9 is a potent, selective and ATP-competitive polo-like kinase 1 (PLK1) inhibitor with an IC50 of 500 nM. Cyclapolin 9 is inactive against other kinases .
    Cyclapolin <em>9</em>
  • HY-W016388

    9-Hydroxyfluorene

    Dopamine Receptor Drug Metabolite Neurological Disease
    9-Fluorenol (9-Hydroxyfluorene; compound 3) is a dopamine (DAT) inhibitor with IC50 value of 9 µM. 9-Fluorenol is a major metabolite of compound developed as a wake promoting agent. 9-Fluorenol shows wake promotion activity in vivo .
    <em>9</em>-Fluorenol
  • HY-N10702

    Ser/Thr Protease Cardiovascular Disease
    PCSK9-IN-9 is an isocoumarins of natural origin. PCSK9-IN-9 can inhibit proprotein convertase subtilisin-kexin type 9 (PCSK9), IDOL, and SREBP2 mRNA expression. PCSK9-IN-9 inhibits PCSK9 with an IC50 value of 11.9 μM .
    PCSK<em>9</em>-IN-<em>9</em>
  • HY-124844

    AZA-9

    HuR Cancer
    Azaphilone-9 (AZA-9) is an inhibitor of HuR-ARE RNA interaction (IC50=1.2 μM) by binding RNA-binding protein Hu antigen R (HuR). The HuR-RNA interactions stabilize many oncogenic mRNAs in tumors. Thus Azaphilone-9 potentially inhibit cancer cell growth and progression .
    Azaphilone-<em>9</em>
  • HY-W110999S

    Isotope-Labeled Compounds Others
    9-Nitroanthracene-d9 is the deuterium labeled 9-Nitroanthracene[1].
    <em>9</em>-Nitroanthracene-d<em>9</em>
  • HY-131501

    Others Metabolic Disease
    Menaquinone 9 is a vitamin K2 (HY-109569) analog. Menaquinone 9 acts as a prothrombogenic agent and functional electron transfer component in nitrate reductase .
    Menaquinone <em>9</em>
  • HY-157604

    DNA/RNA Synthesis Cancer
    DHX9-IN-9 (509) is a RNA helicase DHX9 inhibitor, with an EC50 of 0.0177 μM in DHX9 cellular target engagement. Used in cancer research .
    DHX<em>9</em>-IN-<em>9</em>
  • HY-113943A

    (±)9-HETE

    Endogenous Metabolite Others
    9-HETE, a monohydroxy fatty acid, is the lipoxygenase metabolite of arachidonic acid (HY-109590) .
    <em>9</em>-HETE
  • HY-116302

    MMP Neurological Disease Inflammation/Immunology
    MMP-9-IN-9 (compound 4f) is a slective MMP-9 inhibitor with an IC50 of 5 nM. MMP-9-IN-9 shows selective for MMP-9 over MMP-1 and MMP-13. MMP-9-IN-9 shows strong anti-inflammatory and neuroprotective effects .
    MMP-<em>9</em>-IN-<em>9</em>
  • HY-101329S

    9-Anthracenecarboxylic acid-d9

    Chloride Channel Others
    Anthracene-9-carboxylic acid-d9 is the deuterium labeled Anthracene-9-carboxylic acid[1]. Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca2+-activated Cl- currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells[2].
    Anthracene-<em>9</em>-carboxylic acid-d<em>9</em>
  • HY-19735
    KJ Pyr 9
    5 Publications Verification

    c-Myc Autophagy Cancer
    KJ Pyr 9 is an inhibitor of MYC with a Kd of 6.5 nM in in vitro assay.
    KJ Pyr <em>9</em>
  • HY-78884

    Amino Acid Derivatives Cancer
    Anticancer agent 9, a glycine derivative, is an anticancer agent. Anticancer agent 9 can inhibit tumor cells viability of myelogenous leukemia and human prostate cancer .
    Anticancer agent <em>9</em>
  • HY-139845

    HIV Infection
    Antiviral agent 9 reaches a single-digit picomolar EC50 value (0.006 nM) against HIV-1 and nearly 300-fold higher selectivity index (SI) compared to tenofovir alafenamide fumarate (TAF).
    Antiviral agent <em>9</em>
  • HY-125786

    DNA Stain Others
    Solvent violet 9 is a dye for recognizing DNA .
    Solvent violet <em>9</em>
  • HY-115905

    Parasite Infection
    Antimalarial agent 9 (Compound 11) is a potent antimalarial agent. Antimalarial agent 9 is a quinoline-imidazole derivative compound. Antimalarial agent 9 exhibits significant antimalarial efficacy in-vitro against both CQ-sensitive (IC50-0.14 μM) and MDR strain (IC50-0.41 μM) with minimal cytotoxicity and high selectivity .
    Antimalarial agent <em>9</em>
  • HY-143582

    Others Cancer
    ATX inhibitor 9 is a potent inhibitor of ATX. ATX inhibitor 9 is a thickened heteroaryl derivatives compound. Autotaxin (ATX), also known as ENPP2, is a secreted enzyme that is highly expressed mainly in cancer cells, bronchial epithelial cells and alveolar macrophages in the lung. ATX inhibitor 9 has the potential for the research of cancer or fibrous degenerative disease (extracted from patent WO2021078227A1, compound 3) .
    ATX inhibitor <em>9</em>
  • HY-147897

    Apoptosis
    Apoptosis inducer 9 induces apoptosis with IC50 value of 4.21 μM. Apoptosis inducer 9 induces apoptosis through the mitochondrial pathway and enhance the expression of Cl-caspase-3, Cl-caspase-9 and Cl-PARP. Apoptosis inducer 9 can be used the potential to develop new anti-proliferative agents .
    Apoptosis inducer <em>9</em>
  • HY-147315

    CFTR Others
    CFTR corrector 9 (compound 42) is a cystic fibrosis transmembrane conductance regulator (CFTR) modulator. CFTR corrector 9 can be used for researching cystic fibrosis (CF) and other CFTR associated disorders .
    CFTR corrector <em>9</em>
  • HY-148210

    AMPK Metabolic Disease
    AMPK activator 9 (ZM-6) is a potent AMPK (α2β1γ1) activator with an EC50 value of 1.1 µM. AMPK activator 9 has the potential for the research of type 2 diabetes .
    AMPK activator <em>9</em>
  • HY-Q40175

    Parasite Infection
    Antitrypanosomal agent 9 (compound 1) is a potent antitrypanosomal agent. Antitrypanosomal agent 9 shows inhibitory activity against T. b. brucei, with an IC50 of 1.15 μM. Antitrypanosomal agent 9 can be used for human African trypanosomiasis (HAT) research .
    Antitrypanosomal agent <em>9</em>
  • HY-101329

    9-Anthracenecarboxylic acid

    Anthracene-9-carboxylic acid (9-Anthracenecarboxylic acid) is an anthracene derivative traditionally used to block and identify Ca 2+-activated Cl - currents (CaCCs) in various cell types, like diverse smooth muscle cells, epithelial cells and salivary gland cells .
    Anthracene-<em>9</em>-carboxylic acid
  • HY-124638

    MNK Cancer
    MNK inhibitor 9 is a potent and selective inhibitor of MNK1/2 with IC50 values of 0.003 µM and 0.003 µM for MNK1 and MNK2 respectively. MNK inhibitor 9 has good cell permeability. MNK inhibitor 9 can be used in tumor related research .
    MNK inhibitor <em>9</em>
  • HY-155651

    Bacterial Infection
    Tuberculosis inhibitor 9 (compound 3d) is a 3-methoxy-2-phenylimidazo[1,2-b]pyridazine derivative that shows highly active against Mycobacterium tuberculosis (MIC90 of 0.64 μM) and Mycobacterium marinum (MIC90 of 0.64 μM) .
    Tuberculosis inhibitor <em>9</em>
  • HY-149429

    PPAR Metabolic Disease
    PPARδ agonist 9 (compound 21) is a PPARδ agonist (EC50: 3.6 nM). PPARδ agonist 9 has in vivo efficacy, reducing serum levels of MCP-1 in mice and significantly inhibiting atherosclerosis progression in the LDLr-KO model (inhibition rate: 50-60%) .
    PPARδ agonist <em>9</em>
  • HY-43565

    Others Cancer
    Exatecan intermediate 9 is an intermediate for the synthesis of Exatecan (HY-13631). Exatecan (DX-8951) is a common toxin component in ADC preparation (ADC Cytotoxin) and an inhibitor of DNA topoisomerase I (IC50=2.2 μM) .
    Exatecan intermediate <em>9</em>
  • HY-160058

    Others Cancer
    GMT 9 aptamer sodium is a nucleic acid aptamer targeting different glioblastoma cell lines and exhibits high affinity .
    GMT <em>9</em> aptamer sodium
  • HY-160003

    PPAR Metabolic Disease
    PPARγ agonist 9 is an agonist of PPARγ. PPARγ agonist 9 is the analogue of lysophosphatidic acid with an EC50 more than 10 μM for LPA3 receptor .
    PPARγ agonist <em>9</em>
  • HY-161153

    Apoptosis Cancer
    Microtubule inhibitor 9 (Compound O-7) is a 2-Aryl-1H-benzo [d] imidazole derivative with in vitro anticancer activity. Microtubule inhibitor 9 can induce cell cycle arrest at the G2/M phase and early apoptosis. Microtubule inhibitor 9 inhibits cancer cell migration by inhibiting wound healing and colony formation .
    Microtubule inhibitor <em>9</em>
  • HY-W590683

    Liposome CRISPR/Cas9 Others
    9A1P9 is a multi-tail ionizable cationic phospholipid. 9A1P9 induces membrane destabilization. 9A1P9 can be used for CRISPR-Cas9 gene editing in mice .
    <em>9</em>A1P<em>9</em>
  • HY-100309
    9-Aminocamptothecin
    1 Publications Verification

    9-Amino-20(S)-camptothecin; 9-Amino-CPT

    Topoisomerase Cancer
    9-Aminocamptothecin (9-Amino-CPT) is a topoisomerase I inhibitor with potent anticancer activity .
    <em>9</em>-Aminocamptothecin
  • HY-N9101

    Others Cancer
    4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan is a lignans that can be isolated from the Viburnum foetidum. 4,4'-Dihydroxy-3,3',9-trimethoxy-9,9'-epoxylignan has cytotoxicity against A549, SK-OV-3, SKMEL-2 and HCT15 cell line with IC50s of 67.14, 67.38, 64.11 and 76.31 μg/mL, respectively .
    4,4'-Dihydroxy-3,3',<em>9</em>-trimethoxy-<em>9</em>,<em>9</em>'-epoxylignan
  • HY-N1446S5

    9-cis-Octadecenoic acid-d9; 9Z-Octadecenoic acid-d9

    Apoptosis Na+/K+ ATPase Endogenous Metabolite Metabolic Disease Cancer
    Oleic acid-d9 is deuterium labeled Oleic acid. Oleic acid is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator[1][2].
    Oleic acid-d<em>9</em>
  • HY-112585

    TMC114-d9; UIC-94017-d9

    HIV HIV Protease Infection Inflammation/Immunology
    Darunavir-d9 (TMC114-d9) is the deuterium labeled Darunavir. Darunavir (TMC114), an orally active next generation HIV protease inhibitor, has a similar antiviral activity against the mutant and the wild-type viruses. Darunavir (TMC114) is potent against laboratory HIV-1 strains and primary clinical isolates (IC50 = 0.003 μM; IC90 = 0.009 μM) with minimal cytotoxicity .
    Darunavir-d<em>9</em>
  • HY-124759

    CCR Inflammation/Immunology
    CCR1 antagonist 9 is a potent and selective CCR1 antagonist with an IC50 of 6.8 nM in calcium flux assay .
    CCR1 antagonist <em>9</em>
  • HY-115921

    COX Inflammation/Immunology
    Anti-inflammatory agent 9 (compound 28) is a tilomisole-based benzimidazothiazole derivative. Anti-inflammatory agent 9 expresses activity on COX-2 enzyme more than COX-1. Anti-inflammatory agent 9 is orally active .
    Anti-inflammatory agent <em>9</em>
  • HY-144807

    Carbonic Anhydrase Cancer
    Carbonic anhydrase inhibitor 9 is a potent carbonic anhydrase (CA) inhibitor with Kis of 56.4 and 56.9 nM for hCA II and IX, respectively. Antiproliferative activity .
    Carbonic anhydrase inhibitor <em>9</em>
  • HY-146189

    Topoisomerase Apoptosis Cancer
    Topoisomerase II inhibitor 9 (Compound 19b) is a Topo II inhibitor with an IC50 of 0.97 μM. Topoisomerase II inhibitor 9 is also a classical DNA-intercalator with an IC50 of 43.51 μM. Topoisomerase II inhibitor 9 arrests the cell cycle at the G2/M phase and induces apoptosis in Hep G‐2 cells .
    Topoisomerase II inhibitor <em>9</em>
  • HY-147854

    Raf Apoptosis Cancer
    B-Raf IN 9 (compound 8b) is a potent B-Raf inhibitor, with an IC50 of 24.79 nM. B-Raf IN 9 induces apoptosis and shows cell cycle arrest at G2/M phase. B-Raf IN 9 exhibits potent antitumor activity against human prostate cancer PC-3 cell line, with an IC50 of 7.83 µM .
    B-Raf IN <em>9</em>
  • HY-147979

    CXCR Infection Cancer
    CXCR4 antagonist 9 (Compound 2) is a CXCR4 antagonist with an IC50 of 15 nM. CXCR4 antagonist 9 inhibits CXCL12 induced cytosolic calcium increase with an IC50 of 1.3 nM .
    CXCR4 antagonist <em>9</em>
  • HY-116530

    9-CP-Ade mesylate

    Adenylate Cyclase Others Neurological Disease
    9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate) is a stable non-competitive adenylate cyclase inhibitor with cell permeable properties .
    <em>9</em>-Cyclopentyladenine monomethanesulfonate
  • HY-D1545

    Acid Violet 9

    Fluorescent Dye Others
    Violamine R (Acid Violet 9) is a potent fluorophore. Violamine R shows environment and temperature-dependent photoluminescence (PL) intermittency in poly(vinyl alcohol) (PVOH) and potassium acid phthalate (KAP). Violamine R can be used to measure the temperatures spanning the glass-transition temperature (Tg) of the polymer host by the fluorescence intermittency or blinking in poly(vinyl alcohol) (PVA) .
    Violamine <em>R</em>
  • HY-151419

    Fungal Infection
    Chitin synthase inhibitor 9 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal activity. Chitin synthase inhibitor 9 can be used in the research of fungi infection .
    Chitin synthase inhibitor <em>9</em>
  • HY-148203

    Bcl-2 Family Cancer
    Mcl-1 inhibitor 9 (example 2) is a myeloid cell leukemia 1 (Mcl-1) inhibitor with IC50 value of 0.21889 nM. Mcl-1 inhibitor 9 shows anti-tumor activity .
    Mcl-1 inhibitor <em>9</em>

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