ADAM9 Antibody (YA1428)

製品番号: HY-P81683: データシート User Guide for Antibodies
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ADAM9 Antibody (YA1428) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ADAM9.

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容量		在庫状況
50 μL		お問い合わせ
100 μL		お問い合わせ

* アイテムを追加する前、数量をご選択ください

おすすめ:

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
説明
参考文献

製品説明

ADAM9 Antibody (YA1428) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ADAM9.

Host

Rabbit

Clonality

Recombinant, Monoclonal

分子量

Predicted band size: 90 kDa;

Observed band size: 90 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human

SwissProt ID

Q13443

Gene ID

8754 [NCBI]

Immunogen

Recombinant human ADAM9 protein

Application &
Dilution Ratio

Application	Dilution Ratio
FC FC: Flow Cytometry	1:50-1:100
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Sensitivity	Endogenous	純度	Affinity Chromatography
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG

Appearance

Liquid

Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

輸送条件

Shipping with blue ice.

Background

Function：Metalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins; May act as alpha-secretase for amyloid precursor protein (APP)

Subcellular Localization：Cell membrane; Single-pass type I membrane protein; Secreted

Expression：
Tissue_specificity:Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart

Isoforms & Post-Translational Modification：Q13443 has 2 isomers: Q13443-1: 90556 Da (predicted); Q13443-2: 72359 Da (predicted).
Proteolytically cleaved in the trans-Golgi network before it reaches the plasma membrane to generate a mature protein. The removal of the pro-domain occurs via cleavage at two different sites. Processed most likely by a pro-protein convertase such as furin, at the boundary between the pro-domain and the catalytic domain. An additional upstream cleavage pro-protein convertase site (Arg-56/Glu-57) has an important role in the activation of ADAM9;Phosphorylation is induced in vitro by phorbol-12-myristate-13-acetate (PMA)

Subunit：Interacts with SH3GL2 and SNX9 through its cytoplasmic tail (PubMed:10531379). Interacts with ITGA6

Database

Entrez Gene: 8754 Human

SwissProt: Q13443 Human

OMIM: 612775 Human

Research Field

Neuroscience

Synonyms

CORD9; MCMP; MDC9; Mltng

ドキュメンテーション

User Guide for Antibodies (1077 KB)

参考文献

[1]. /biology-dictionary/sk-ov-3-cell.html [Content Brief]