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Cat. No.: HY-P81683

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ADAM9 Antibody (YA1428)

Name: ADAM9 Antibody (YA1428)
Brand: MedChemExpress
SKU: HY-P81683
Availability: PreOrder

(Synonyms: CORD9; MCMP; MDC9; Mltng)

ADAM9 Antibody (YA1428) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ADAM9.

For research use only. We do not sell to patients.

Host:
Rabbit
Isotype:
IgG
Application:
FC, ELISA
Reactivity :
Human

Formulation:
Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Conjugation:
Non-conjugated

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Applications
Product Details
Product Properties
- Appearance
- Formulation
- Storage & Stability
- Shipping
Background
Documentation
Help & FAQs
Classifications
Bioz

Applications

Application	FC FC: Flow Cytometry	ELISA ELISA: Enzyme Linked Immunosorbent Assay
Dilution Ratio	1:50-1:100	1:10000

Product Details

Description

ADAM9 Antibody (YA1428) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to ADAM9.

Host Rabbit
Clonality Recombinant, Monoclonal
Species Reactivity
Human
Observed Molecular Weight

Observed band size: 90 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Calculated Molecular Weight Predicted band size: 90 kDa

Species Reactivity Database

Entrez Gene: 8754 Human

SwissProt: Q13443 Human

OMIM: 612775 Human

Immunogen

Recombinant human ADAM9 protein

Sensitivity

Endogenous

Purification

Affinity Chromatography

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

Appearance

Liquid
Formulation

Supplied in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
Shipping

Shipping with blue ice.

Background

Function

ADAM9 is a Metalloprotease that cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as TEK, KDR, EPHB4, CD40, VCAM1 and CDH5. May mediate cell-cell, cell-matrix interactions and regulate the motility of cells via interactions with integrins; May act as alpha-secretase for amyloid precursor protein (APP)
Subcellular Localization

Cell membrane; Single-pass type I membrane protein; Secreted
Expression

Tissue_specificity:Widely expressed. Expressed in chondrocytes. Isoform 2 is highly expressed in liver and heart
Isoforms & Post-Translational Modification

Q13443 has 2 isomers: Q13443-1: 90556 Da (predicted); Q13443-2: 72359 Da (predicted).
Proteolytically cleaved in the trans-Golgi network before it reaches the plasma membrane to generate a mature protein. The removal of the pro-domain occurs via cleavage at two different sites. Processed most likely by a pro-protein convertase such as furin, at the boundary between the pro-domain and the catalytic domain. An additional upstream cleavage pro-protein convertase site (Arg-56/Glu-57) has an important role in the activation of ADAM9;Phosphorylation is induced in vitro by phorbol-12-myristate-13-acetate (PMA)
Subunit

Interacts with SH3GL2 and SNX9 through its cytoplasmic tail (PubMed:10531379). Interacts with ITGA6
SwissProt ID

Q13443
Gene ID

8754 [NCBI]
Synonyms

CORD9; MCMP; MDC9; Mltng
Research Field

Neuroscience