Primulaceae

5-O-Methylembelin is a natural isocoumarin that inhibits PCSK9, inducible degrader of the low-density lipoprotein receptor (IDLR), and sterol regulatory element binding protein 2 (SREBP2) mRNA expression.

Chlorogenic acid butyl ester, a caffeoylquinic acid, is a potent melanogenesis inhibitor. Chlorogenic acid butyl ester inhibits the expression of microphtalmia-associated transcription factor (MITF), tyrosinase, tyrosinerelated protein 1 (TRP-1), and TRP-2. Chlorogenic acid butyl ester also shows antioxidant activity.

23-Hydroxylongispinogenin (12-Oleanene-3β,16β,23,28-tetrol) is extracted from Lysimachia heterogenea Klatt. Lysimachia heterogenea Klatt is a perennial herb, which is used as a folk medicine in subduing swelling and detoxicating in China. The effective fraction LH-1 of L. heterogene has antitumor activity.

Myrseguinoside A is a monoterpene glucoside found in the fruits of Myrsine seguinii. Myrseguinoside A does not exhibit significant DPPH radical-scavenging activity or growth inhibitory activity toward human cancer cells. Myrseguinoside A can be used for cancer research.

Kaempferol-3-O-glu-rha-glu is an insecticide. Kaempferol-3-O-glu-rha-glu inhibits activities of the enzymes CarE, GSTs, MFO, and AChE. Kaempferol-3-O-glu-rha-glu exhibits cytotoxicity and disrupts mitochondrial membrane potential and increases ROS production. Kaempferol-3-O-glu-rha-glu can be used for the infection.

Miconidin is a compound found in Primula obconica. Miconidin can be used as possible allergen.

Capilliposide I is a tetrasaccharide flavonol glycoside found in the whole herbs of Lysimachia capillipes.

Capilliposide II is a flavonol glycoside found in the whole herbs of Lysimachia capillipes. Capilliposide II has the structure kaempferol-3-O---β-D-galactopyranoside.

Capilliposide B is a natural product that can be found in Lysimachia capillipes?Hemsl..

Capilliposide C is a natural product that can be found in Lysimachia capillipes?Hemsl..

Myricetin 3-O-(3''-O-galloyl)-α-L-rhamnopyranoside is a natural flavonoid that can be found in Ardisia splendens.

4-O-Galloylbergenin is a bergenin derivative that can be isolated from the rhizome of Ardisia gigantifolia.

PCSK9-IN-9 is an isocoumarins of natural origin. PCSK9-IN-9 can inhibit proprotein convertase subtilisin-kexin type 9 (PCSK9), IDOL, and SREBP2 mRNA expression. PCSK9-IN-9 inhibits PCSK9 with an IC₅₀ value of 11.9 μM.

Methyl 2,6-dihydroxybenzoate is a phenolic compound that can be isolated from whole flowers and corolla of Primula spectabilis. Methyl 2,6-dihydroxybenzoate can be used as a precursor for the synthesis of other useful compounds.

Ardisianone is a component with an alkyl benzoquinone structure that can be isolated from Ardisia virens Kurz and Ardisia compressa tea extract. Ardisianone exhibits potent antileukemic activity, particularly against HL-60 cells, with IC₅₀ values of 1.87 μM (24 h) and 1.67 μM (48 h). Ardisianone induces caspase-dependent apoptosis and triggers pyroptosis. Ardisianone can be used for the study of acute myeloid leukemia (AML).

Unedone is a Sesquiterpenoids product that can be isolated from the herbs of Lysimachia clethroides.

Primeverose is a natural product.

(7R,8R)-Dihydrodehydrodiconiferyl alcohol 9-O-β-D-glucoside is a Lignans product that can be isolated from the herbs of Lysimachia clethroides.

Datiscin is a Flavonoids product that can be isolated from the roots of Primula officinalis.