66398-68-3
Chemical Structure
Ardisianone
- CAS No.: 66398-68-3
- Formula:C24H38O5
- Molecular Weight:406.56
InChIKey: CVZNKLNAHBTINT-JOCHJYFZSA-N
SMILES: CCCCCCCCCCCCC[C@@H](OC(C)=O)CC(C(C(OC)=C1)=O)=CC1=O
Biological Activity: Ardisianone is a component with an alkyl benzoquinone structure that can be isolated from Ardisia virens Kurz and Ardisia compressa tea extract. Ardisianone exhibits potent antileukemic activity, particularly against HL-60 cells, with IC50 values of 1.87 μM (24 h) and 1.67 μM (48 h). Ardisianone induces caspase-dependent apoptosis and triggers pyroptosis. Ardisianone can be used for the study of acute myeloid leukemia (AML)[1].
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Ardisianone | Ardisianone is a component with an alkyl benzoquinone structure that can be isolated from Ardisia virens Kurz and Ardisia compressa tea extract. Ardisianone exhibits potent antileukemic activity, particularly against HL-60 cells, with IC50 values of 1.87 μM (24 h) and 1.67 μM (48 h). Ardisianone induces caspase-dependent apoptosis and triggers pyroptosis. Ardisianone can be used for the study of acute myeloid leukemia (AML). | |||||||||||||||||||||
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Keywords
