9-Cyclopentyladenine monomethanesulfonate (Synonyms: 9-CP-Ade mesylate)

Name: 9-Cyclopentyladenine monomethanesulfonate
Brand: MedChemExpress
SKU: HY-116530
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Cat. No.: HY-116530 Purity: 99.95%: Data Sheet
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9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate) is a stable non-competitive adenylate cyclase inhibitor with cell permeable properties.

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9-Cyclopentyladenine monomethanesulfonate 화학구조

CAS No. : 189639-09-6

사이즈	재고	수량

무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
무료 샘플 (0.1 - 0.2 mg)	지금 신청하기
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	해외재고보유	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	해외재고보유	Estimated Time of Arrival: December 31
Solid
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

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This product is a controlled substance and not for sale in your territory.

고객리뷰

Based on 1 Customer Validation

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

9-Cyclopentyladenine monomethylsulfonate (9-CP-Ade mesylate) is a stable non-competitive adenylate cyclase inhibitor with cell permeable properties^[1]^[2].

In Vitro

9-Cyclopentyladenine monomethanesulfonate (200 μM, 30 min) inhibits the activation of cAMP response element binding protein (CREB) and completely blocks neurogenesis in PC12 cells^[1].
9-Cyclopentyladenine monomethanesulfonate (100 μM, 30min) attenuates the effect of relaxin on mechanical activity and prevents relaxin-induced hyperpolarization thereby being involved in the regulation of relaxin on ileal smooth muscle activity in female CD1 Swiss mice^[2].
9-Cyclopentyladenine monomethanesulfonate (100 μM, 6 hours) promotes restoration of the keratinocyte permeability barrier by inhibiting the synthesis of cAMP in male hairless mice^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

299.35

화학식

C₁₁H₁₇N₅O₃S

CAS No.

189639-09-6

Appearance

Solid

Color

White to off-white

SMILES

NC1=C2N=CN(C3CCCC3)C2=NC=N1.CS(=O)(O)=O

선적

Room temperature in continental US; may vary elsewhere.

보관

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

용액&용해도

In Vitro:

H₂O : ≥ 100 mg/mL (334.06 mM)

DMSO : 41.67 mg/mL (139.20 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.3406 mL	16.7029 mL	33.4057 mL
5 mM	0.6681 mL	3.3406 mL	6.6811 mL
10 mM	0.3341 mL	1.6703 mL	3.3406 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.95%

Select Batch:

Data Sheet (275 KB) SDS (252 KB)

COA (250 KB) HNMR (279 KB) LCMS (114 KB)

Handling Instructions (2659 KB)

References

[1]. Ulrike Riese，et al. Militarinone A induces differentiation in PC12 cells via MAP and Akt kinase signal transduction pathways. FEBS Lett. 2004 Nov 19;577(3):455-9. [Content Brief]

[2]. Eglantina Idrizaj，et al. Relaxin influences ileal muscular activity through a dual signaling pathway in mice. World J Gastroenterol. 2018 Feb 28;24(8):882-893. [Content Brief]

[3]. Mitsuhiro Denda, et al. Association of cyclic adenosine monophosphate with permeability barrier homeostasis of murine skin. J Invest Dermatol. 2004 Jan;122(1):140-6. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO / H₂O	1 mM	3.3406 mL	16.7029 mL	33.4057 mL	83.5143 mL
	5 mM	0.6681 mL	3.3406 mL	6.6811 mL	16.7029 mL
	10 mM	0.3341 mL	1.6703 mL	3.3406 mL	8.3514 mL
	15 mM	0.2227 mL	1.1135 mL	2.2270 mL	5.5676 mL
	20 mM	0.1670 mL	0.8351 mL	1.6703 mL	4.1757 mL
	25 mM	0.1336 mL	0.6681 mL	1.3362 mL	3.3406 mL
	30 mM	0.1114 mL	0.5568 mL	1.1135 mL	2.7838 mL
	40 mM	0.0835 mL	0.4176 mL	0.8351 mL	2.0879 mL
	50 mM	0.0668 mL	0.3341 mL	0.6681 mL	1.6703 mL
	60 mM	0.0557 mL	0.2784 mL	0.5568 mL	1.3919 mL
	80 mM	0.0418 mL	0.2088 mL	0.4176 mL	1.0439 mL
	100 mM	0.0334 mL	0.1670 mL	0.3341 mL	0.8351 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

9-Cyclopentyladenine monomethanesulfonate Related Classifications

Neurological Disease Others

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

9-Cyclopentyladenine monomethanesulfonate189639-09-69-CP-AdeAdenylate CyclaseAdenylyl cyclaseAdenylate cyclase inhibitorcAMPACInhibitorinhibitorinhibit

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9-Cyclopentyladenine monomethanesulfonate (Synonyms: 9-CP-Ade mesylate)

고객리뷰

9-Cyclopentyladenine monomethanesulfonate Related Antibodies

Featured Recommendations

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Biological Activity

순도&문서

References

고객리뷰

9-Cyclopentyladenine monomethanesulfonate Related Antibodies

몰농도 계산기

농도 희석 계산기

Complete Stock Solution Preparation Table

9-Cyclopentyladenine monomethanesulfonate Related Classifications

Keywords:

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고객리뷰

Request for HNMR Report

SAFETY DATA SHEET (SDS)

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