1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Coenzyme Q9

Coenzyme Q9 (Synonyms: Ubiquinone Q9; CoQ9; Ubiquinone 9)

Cat. No.: HY-101415 Purity: >98.0%
Handling Instructions

Coenzyme Q9, a nine isoprenyl group-containing member of the ubiquinone family, is a normal constituent of human plasma.

For research use only. We do not sell to patients.

Coenzyme Q9 Chemical Structure

Coenzyme Q9 Chemical Structure

CAS No. : 303-97-9

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1 mg USD 60 In-stock
Estimated Time of Arrival: December 31
5 mg USD 240 In-stock
Estimated Time of Arrival: December 31
10 mg USD 420 In-stock
Estimated Time of Arrival: December 31
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Description

Coenzyme Q9, a nine isoprenyl group-containing member of the ubiquinone family, is a normal constituent of human plasma.

In Vitro

Both CoQ9 and CoQ10 are equally cardioprotective, as evidenced by their abilities to improve left ventricular performance and to reduce myocardial infarct size and cardiomyocyte apoptosis. HPLC analysis reveals that a substantial portion of CoQ9 has been converted into CoQ10[1]. CoQ10 and CoQ9 are components of themitochondrial respiratory chain in mammals and can regulate some mitochondrial proteins/functions. Soybean, corn, and rapeseed oils are very rich sources of CoQ10, whereas CoQ9 has been found in high concentrations in corn oil[2].

In Vivo

The lack of a functional CoQ9 protein in homozygous CoQ9 mutant (CoQ9(X/X)) mice causes a severe reduction in the CoQ7 protein and a widespread CoQ deficiency and accumulation of demethoxyubiquinone. The deficit in CoQ induces a brain-specific impairment of mitochondrial bioenergetics performance, a reduction in respiratory control ratio, ATP levels and ATP/ADP ratio and specific loss of respiratory complex I. These effects lead to neuronal death and demyelinization with severe vacuolization and astrogliosis in the brain of CoQ9 (X/X) mice that consequently die between 3 and 6 months of age[3].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (6.29 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.2575 mL 6.2875 mL 12.5750 mL
5 mM 0.2515 mL 1.2575 mL 2.5150 mL
10 mM --- --- ---
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

795.23

Formula

C₅₄H₈₂O₄

CAS No.

303-97-9

SMILES

O=C1C(OC)=C(OC)C(C(C)=C1C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)/CC/C=C(C)\C)=O

Shipping

Room temperature in continental US; may vary elsewhere

Purity: >98.0%

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Product Name:
Coenzyme Q9
Cat. No.:
HY-101415
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Coenzyme Q9

Cat. No.: HY-101415