B-Raf IN 9
B-Raf IN 9 (compound 8b) is a potent B-Raf inhibitor, with an IC50 of 24.79 nM. B-Raf IN 9 induces apoptosis and shows cell cycle arrest at G2/M phase. B-Raf IN 9 exhibits potent antitumor activity against human prostate cancer PC-3 cell line, with an IC50 of 7.83 µM.
For research use only. We do not sell to patients.
- CAS No.: 2477725-18-9
- Formula: C23H20N4OS
- Molecular Weight:400.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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B-Raf 24.97 ± 0. nM (IC50) |
Chemical Information
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CAS No. 2477725-18-9
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Molecular Weight 400.50
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Formula C23H20N4OS
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SMILES
S=C(NC1=CC=CC=C1)NC2=CC=C(C(CC3)=NN(C4=CC=CC=C4)C3=O)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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