1. Cell Cycle/DNA Damage
  2. Polo-like Kinase (PLK)
  3. Cyclapolin 9

Cyclapolin 9 

Cat. No.: HY-15159
Handling Instructions

Cyclapolin 9 is a potent, selective and ATP-competitive polo-like kinase 1 (PLK1) inhibitor with an IC50 of 500 nM. Cyclapolin 9 is inactive against other kinases.

For research use only. We do not sell to patients.

Cyclapolin 9 Chemical Structure

Cyclapolin 9 Chemical Structure

CAS No. : 40533-25-3

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products

View All Polo-like Kinase (PLK) Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Cyclapolin 9 is a potent, selective and ATP-competitive polo-like kinase 1 (PLK1) inhibitor with an IC50 of 500 nM. Cyclapolin 9 is inactive against other kinases[1][2].

IC50 & Target[2]

PLK1

500 nM (IC50)

In Vitro

Cyclapolin 9 (3 μM) reduces electric field stimulation (EFS)-induced contractions of prostate strips. The α1-adrenergic smooth muscle contraction in the human prostate can be inhibited by Cyclapolin 9[1].

Molecular Weight

307.21

Formula

C₉H₄F₃N₃O₄S

CAS No.

40533-25-3

SMILES

O=C(C1=[N+]([O-])C2=CC(C(F)(F)F)=CC([N+]([O-])=O)=C2S1)N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Cyclapolin 9Cyclapolin9Cyclapolin-9Polo-like Kinase (PLK)PLK1ATP-competitiveantitumorprostateα1-adrenergicInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Cyclapolin 9
Cat. No.:
HY-15159
Quantity:
MCE Japan Authorized Agent: