1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Polo-like Kinase (PLK)
  4. PLK1 Inhibitors

PLK1 Inhibitors

PLK1

PLK2

PLK3

PLK4

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform PLK1 together.

Please try each isoform separately.

PLK1 Specific Inhibitors
Product Name PLK1 PLK2 PLK3 PLK4 PLK1 Selectivity Purity
NMS-1286937
PLK1, IC50: 2 nM
      Selective Inhibitor 99.70%
GSK461364
PLK1, Ki: 2.2 nM
      Selective Inhibitor 99.82%
Rigosertib
PLK1, IC50: 9 nM
PLK2, IC50: 260 nM
    Selective Inhibitor 98.81%
Rigosertib sodium
PLK1, IC50: 9 nM
PLK2, IC50: 260 nM
    Selective Inhibitor 99.49%
Ro3280
PLK1, Kd: 0.09 nM
      Selective Inhibitor 99.28%
TAK-960
PLK1, IC50: 0.8 nM
PLK2, IC50: 16.9 nM
PLK3, IC50: 50.2 nM
  Selective Inhibitor 95.44%
MLN0905
PLK1, IC50: 2 nM
      Selective Inhibitor ≥97.0%
HMN-214
PLK1
      Selective Inhibitor 99.65%
SBE13 Hydrochloride
PLK1, IC50: 200 pM
 
PLK3, IC50: 875 nM
  Selective Inhibitor 98.76%
TAK-960 dihydrochloride
PLK1, IC50: 0.8 nM
PLK2, IC50: 16.9 nM
PLK3, IC50: 50.2 nM
  Selective Inhibitor 99.81%
Cyclapolin 9
PLK1, IC50: 500 nM
      Selective Inhibitor ≥98.0%
Poloxime
PLK1
      Selective Inhibitor ≥95.0%
SBE13
PLK1, IC50: 200 pM
 
PLK3, IC50: 875 nM
  Selective Inhibitor
TAK-960 hydrochloride
PLK1, IC50: 0.8 nM
PLK2, IC50: 16.9 nM
PLK3, IC50: 50.2 nM
  Selective Inhibitor
Volasertib
PLK1, IC50: 0.87 nM
PLK2, IC50: 5 nM
PLK3, IC50: 56 nM
  Pan Inhibitor 99.41%
BI 2536
PLK1, IC50: 0.83 nM
Plk2/Snk, IC50: 3.5 nM
Plk3/Fnk, IC50: 9 nM
  Pan Inhibitor 99.95%
ON1231320
PLK1, IC50: >10 μM
PLK2, IC50: 0.31 μM
PLK3, IC50: >10 μM
PLK4, IC50: >10 μM
Pan Inhibitor
GW843682X
PLK1, IC50: 2.2 nM
 
PLK3, IC50: 9.1 nM
  Pan Inhibitor 99.84%
LFM-A13
Plx1, IC50: 10 μM
 
PLK3, IC50: 61 μM
  Pan Inhibitor 99.97%
TC-S 7005
PLK1, IC50: 214 nM
PLK2, IC50: 4 nM
PLK3, IC50: 24 nM
  Pan Inhibitor ≥99.0%
Poloxin
PLK1 PBD, IC50: 4.8 μM
PLK2 PBD, IC50: 18.7 μM
PLK3 PBD, IC50: 53.9 μM
  Pan Inhibitor 98.96%