1. Signaling Pathways
  2. Cell Cycle/DNA Damage
  3. Polo-like Kinase (PLK)
  4. PLK1 Inhibitors

PLK1 Inhibitors

PLK1

PLK2

PLK3

PLK4

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform PLK1 together.

Please try each isoform separately.

PLK1 Specific Inhibitors
Product Name PLK1 PLK2 PLK3 PLK1 Selectivity Purity
NMS-1286937
PLK1, IC50: 2 nM
    Selective Inhibitor 99.70%
Rigosertib sodium
PLK1, IC50: 9 nM
PLK2, IC50: 260 nM
  Selective Inhibitor 99.49%
GSK461364
PLK1, Ki: 2.2 nM
    Selective Inhibitor 99.82%
Rigosertib
PLK1, IC50: 9 nM
PLK2, IC50: 260 nM
  Selective Inhibitor 98.81%
Ro3280
PLK1, Kd: 0.09 nM
    Selective Inhibitor 99.28%
MLN0905
PLK1, IC50: 2 nM
    Selective Inhibitor 99.94%
TAK-960
PLK1, IC50: 0.8 nM
PLK2, IC50: 16.9 nM
PLK3, IC50: 50.2 nM
Selective Inhibitor 95.44%
SBE13 Hydrochloride
PLK1, IC50: 200 pM
 
PLK3, IC50: 875 nM
Selective Inhibitor 98.76%
HMN-214
PLK1
    Selective Inhibitor 99.65%
TAK-960 dihydrochloride
PLK1, IC50: 0.8 nM
PLK2, IC50: 16.9 nM
PLK3, IC50: 50.2 nM
Selective Inhibitor 99.81%
Cyclapolin 9
PLK1, IC50: 500 nM
    Selective Inhibitor >98.0%
Poloxime
PLK1
    Selective Inhibitor >95.0%
Volasertib
PLK1, IC50: 0.87 nM
PLK2, IC50: 5 nM
PLK3, IC50: 56 nM
Pan Inhibitor 99.55%
BI 2536
PLK1, IC50: 0.83 nM
Plk2/Snk, IC50: 3.5 nM
Plk3/Fnk, IC50: 9 nM
Pan Inhibitor 99.95%
GW843682X
PLK1, IC50: 2.2 nM
 
PLK3, IC50: 9.1 nM
Pan Inhibitor 99.84%
Poloxin
PLK1 PBD, IC50: 4.8 μM
PLK2 PBD, IC50: 18.7 μM
PLK3 PBD, IC50: 53.9 μM
Pan Inhibitor 98.96%
LFM-A13
Plx1, IC50: 10 μM
 
PLK3, IC50: 61 μM
Pan Inhibitor 99.97%
TC-S 7005
PLK1, IC50: 214 nM
PLK2, IC50: 4 nM
PLK3, IC50: 24 nM
Pan Inhibitor 99.39%