660868-91-7
660868-91-7
Chemical Structure
GW843682X
Synonym(s): GW843682
- CAS No.: 660868-91-7
- Formula:C22H18F3N3O4S
- Molecular Weight:477.46
IUPAC Name: 5-(5,6-dimethoxy-1H-benzo[d]imidazol-1-yl)-3-((2-(trifluoromethyl)benzyl)oxy)thiophene-2-carboxamide
InChIKey: JSKUWFIZUALZLX-UHFFFAOYSA-N
SMILES: O=C(C1=C(OCC2=CC=CC=C2C(F)(F)F)C=C(N3C4=CC(OC)=C(OC)C=C4N=C3)S1)N
Biological Activity: GW843682X is a selective, ATP-competitive inhibitor of PLK1 and PLK3, with IC50s of 2.2 nM and 9.1 nM, respectively, and is also >100-fold selective against ～30 other kinases.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GW843682X | 99.89% | GW843682X is a selective, ATP-competitive inhibitor of PLK1 and PLK3, with IC50s of 2.2 nM and 9.1 nM, respectively, and is also >100-fold selective against ～30 other kinases. | ||||||||||||||||||||
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Keywords
