1062243-51-9
1062243-51-9
Chemical Structure
Ro3280
- CAS No.: 1062243-51-9
- Formula:C27H35F2N7O3
- Molecular Weight:543.61
IUPAC Name: 4-((9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
InChIKey: DJNZZLZKAXGMMC-UHFFFAOYSA-N
SMILES: COC1=C(NC2=NC(N(C3CCCC3)CC(F)(F)C(N4C)=O)=C4C=N2)C=CC(C(NC5CCN(C)CC5)=O)=C1
Biological Activity: Ro3280 is a potent, highly selective inhibitor of PLK1 with an IC50 and a Kd of 3 nM and 0.09 nM, respectively, and nearly has no effect on PLK2 and PLK3.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ro3280 | 99.46% | Ro3280 is a potent, highly selective inhibitor of PLK1 with an IC50 and a Kd of 3 nM and 0.09 nM, respectively, and nearly has no effect on PLK2 and PLK3. | ||||||||||||||||||||
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Keywords
