1. Cell Cycle/DNA Damage
  2. Polo-like Kinase (PLK)
  3. TC-S 7005

TC-S 7005 

Cat. No.: HY-108597 Purity: 99.39%
Handling Instructions

TC-S 7005 is a Polo-like kinases (Plks) inhibitor with IC50s of 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively.

For research use only. We do not sell to patients.

TC-S 7005 Chemical Structure

TC-S 7005 Chemical Structure

CAS No. : 1082739-92-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 396 In-stock
Estimated Time of Arrival: December 31
5 mg USD 360 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products

View All Polo-like Kinase (PLK) Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review


TC-S 7005 is a Polo-like kinases (Plks) inhibitor with IC50s of 4 nM, 24 nM and 214 nM for Plk2, Plk3, and Plk1, respectively[1].

IC50 & Target[1]


4 nM (IC50)


24 nM (IC50)


214 nM (IC50)

In Vitro

TC-S 7005 markedly induces myofibroblast differentiation and reduces fibroblast proliferation rates[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay[2]

Cell Line: Primary human SR fibroblasts
Concentration: 1 μM
Incubation Time: 7 days
Result: Markedly induced myofibroblast differentiation and reduced fibroblast proliferation rates.
Molecular Weight







C[[email protected]](NC1=CC2=C(ON=C2C3=CC=C(OCO4)C4=C3)C=N1)C5=CC=CC=C5


Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (347.82 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7826 mL 13.9128 mL 27.8257 mL
5 mM 0.5565 mL 2.7826 mL 5.5651 mL
10 mM 0.2783 mL 1.3913 mL 2.7826 mL
*Please refer to the solubility information to select the appropriate solvent.

Purity: 99.39%

  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2


TC-S 7005Polo-like Kinase (PLK)Inhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name



Applicant Name *


Email address *

Phone number *


Organization name *

Department *


Requested quantity *

Country or Region *



Bulk Inquiry

Inquiry Information

Product Name:
TC-S 7005
Cat. No.:
MCE Japan Authorized Agent: