Polo-like Kinase (PLK) Inhibitors

PLK1

PLK2

PLK3

PLK4

Polo-like Kinase (PLK) Degraders & Inhibitors

Product Name	PLK1	PLK2	PLK3	PLK4	Purity
Wortmannin			PLK3, IC₅₀: 48 nM		99.86%
BI 2536	PLK1, IC₅₀: 0.83 nM	Plk2/Snk, IC₅₀: 3.5 nM	Plk3/Fnk, IC₅₀: 9 nM		99.95%
Volasertib	PLK1, IC₅₀: 0.87 nM	PLK2, IC₅₀: 5 nM	PLK3, IC₅₀: 56 nM		99.41%
Onvansertib	PLK1, IC₅₀: 2 nM				99.55%
Centrinone				PLK4, Ki: 0.16 nM PLK4 (G95L), Ki: 68.57 nM	98.57%
Ocifisertib				PLK4, IC₅₀: 2.8 nM	98.45%
PLK4-IN-4				PLK4, IC₅₀: 7.9 nM
PROTAC PLK1 Degrader-1	PLK1
GSK461364	PLK1, Ki: 2.2 nM				99.82%
Centrinone-B				PLK4, Ki: 0.59 nM PLK4 (G95L), Ki: 497.53 nM	98.71%
Rigosertib	PLK1, IC₅₀: 9 nM	PLK2, IC₅₀: 260 nM			98.35%
Rigosertib sodium	PLK1, IC₅₀: 9 nM	PLK2, IC₅₀: 260 nM			99.57%
GW843682X	PLK1, IC₅₀: 2.2 nM		PLK3, IC₅₀: 9.1 nM		99.75%
Ro3280	PLK1, Kd: 0.09 nM				98.87%
TAK-960	PLK1, IC₅₀: 0.8 nM	PLK2, IC₅₀: 16.9 nM	PLK3, IC₅₀: 50.2 nM		99.75%
(Z)-LFM-A13	Plx1, IC₅₀: 10 μM		PLK3, IC₅₀: 61 μM		99.97%
MLN0905	PLK1, IC₅₀: 2 nM				99.94%
TC-S 7005	PLK1, IC₅₀: 214 nM	PLK2, IC₅₀: 4 nM	PLK3, IC₅₀: 24 nM		99.56%
HMN-214	PLK1				99.25%
(1E)-CFI-400437 dihydrochloride				PLK4, IC₅₀: 0.6 nM	98.89%
Poloxin	PLK1 PBD, IC₅₀: 4.8 μM	PLK2 PBD, IC₅₀: 18.7 μM	PLK3 PBD, IC₅₀: 53.9 μM		98.01%
Plogosertib	PLK1, IC₅₀: 3 nM	PLK2, IC₅₀: 149 nM	PLK3, IC₅₀: 393 nM		99.95%
SBE13 Hydrochloride	PLK1, IC₅₀: 200 pM		PLK3, IC₅₀: 875 nM		99.66%
TAK-960 dihydrochloride	PLK1, IC₅₀: 0.8 nM	PLK2, IC₅₀: 16.9 nM	PLK3, IC₅₀: 50.2 nM		99.19%
Cyclapolin 9	PLK1, IC₅₀: 500 nM				99.16%
Dihydrobaicalein	PLK1				99.94%
LFM-A13	Plx1, IC₅₀: 10 μM		PLK3, IC₅₀: 61 μM
SBE13	PLK1, IC₅₀: 200 pM		PLK3, IC₅₀: 875 nM
Poloxime	PLK1
Volasertib trihydrochloride	PLK1, IC₅₀: 0.87 nM	PLK2, IC₅₀: 5 nM	PLK3, IC₅₀: 56 nM
(E/Z)-Rigosertib sodium	PLK1
BTO-1	Plx1
PLK1-IN-6	PLK1, IC₅₀: 0.45 nM	PLK2, IC₅₀: 5.73 nM	PLK3, IC₅₀: 7.56 nM
PLK1/BRD4-IN-1	PLK1, IC₅₀: 22 nM
PLK1/BRD4-IN-5	PLK1, IC₅₀: 0.3 nM
YLT-11	PLK1, Kd: >10000 nM	PLK2, Kd: 653 nM	PLK3, Kd: >10000 nM	PLK4, Kd: 5.2 nM
PLK4-IN-3				PLK4, IC₅₀: ≤ 0.1 μM
CZS-241				PLK4, IC₅₀: 2.6 nM
PLK1-IN-5	PLK1, IC₅₀: <500 nM
TAK-960 hydrochloride	PLK1, IC₅₀: 0.8 nM	PLK2, IC₅₀: 16.9 nM	PLK3, IC₅₀: 50.2 nM

Name
Email *

	Sorry, but the email address you supplied was invalid.