929095-18-1

GSK461364 Chemical Structure
929095-18-1

Chemical Structure

GSK461364

Synonym(s): GSK461364A

  • CAS No.: 929095-18-1
  • Formula:C27H28F3N5O2S
  • Molecular Weight:543.60

IUPAC Name: (R)-5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-(1-(2-(trifluoromethyl)phenyl)ethoxy)thiophene-2-carboxamide

InChIKey: ZHJGWYRLJUCMRT-QGZVFWFLSA-N

SMILES: O=C(C(SC(N1C=NC2=CC=C(C=C12)CN3CCN(CC3)C)=C4)=C4O[C@@H](C5=CC=CC=C5C(F)(F)F)C)N

Biological Activity: GSK461364 is a selective, reversible and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with a Ki value of 2.2 nM.

Cat. No. Product Name Purity Description Pricing
HY-50877
GSK461364 98.68% GSK461364 is a selective, reversible and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with a Ki value of 2.2 nM.
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