1034616-18-6

Onvansertib Chemical Structure
1034616-18-6

Chemical Structure

Onvansertib

Synonym(s): NMS-1286937; NMS-P937

  • CAS No.: 1034616-18-6
  • Formula:C24H27F3N8O3
  • Molecular Weight:532.52

IUPAC Name: 1-(2-hydroxyethyl)-8-((5-(4-methylpiperazin-1-yl)-2-(trifluoromethoxy)phenyl)amino)-4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline-3-carboxamide

InChIKey: QHLVBNKYJGBCQJ-UHFFFAOYSA-N

SMILES: O=C(C1=NN(CCO)C2=C1CCC3=CN=C(NC4=CC(N5CCN(C)CC5)=CC=C4OC(F)(F)F)N=C23)N

Biological Activity: NMS-1286937 is a potent, selective and orally available PLK1 inhibitor, with an IC50 of 2 nM.

Cat. No. Product Name Purity Description Pricing
HY-15828 		Onvansertib 99.86% NMS-1286937 is a potent, selective and orally available PLK1 inhibitor, with an IC50 of 2 nM.
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