BTBD9 Protein, Human (sf9)
The BTBD9 protein is invovled in regulating hippocampal synaptic plasticity and learning and memory in mice. BTBD9 is involved in formation of the limbs and cell fate determination in the developing Drosophila melanogaster. BTBD9 is also a genetic risk factor of Restless legs syndrome (RLS). BTBD9 alleviates Mn-induced oxidative stress and neurotoxicity in Caenorhabditis elegans. via regulation of insulin/insulin-like growth factor signaling pathway. BTBD9 Protein, Human (sf9) is the recombinant human-derived BTBD9 protein, expressed by sf9 insect cells , with tag free.
- Species: Human
- Source: Sf9 insect cells
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Storage:Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
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Biological Activity
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Technical Parameters
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Product Properties
- Documentation
- Help & FAQs
Biological Activity
Description
The BTBD9 protein is invovled in regulating hippocampal synaptic plasticity and learning and memory in mice. BTBD9 is involved in formation of the limbs and cell fate determination in the developing Drosophila melanogaster. BTBD9 is also a genetic risk factor of Restless legs syndrome (RLS). BTBD9 alleviates Mn-induced oxidative stress and neurotoxicity in Caenorhabditis elegans. via regulation of insulin/insulin-like growth factor signaling pathway[1][2][3]. BTBD9 Protein, Human (sf9) is the recombinant human-derived BTBD9 protein, expressed by sf9 insect cells , with tag free.
Background
The BTBD9 protein contains a BTB/POZ domain and a BACK domain. BTBD9 is widely expressed in the central nervous system of mouse,such as in the thalamus, hypothalamus,etc. Therefore, BTBD9 is invovled in regulating hippocampal synaptic plasticity and learning and memory. BTBD9 is involved in formation of the limbs and cell fate determination in the developing Drosophila melanogaster[1][2].In additon, BTBD9 is also a genetic risk factor of Restless legs syndrome (RLS). Btbd9 knockout mice show motor restlessness, sleep disruption, altered sensory perception and serum iron levels, as well as enhanced fear memory. BTBD9 alleviates Mn-induced oxidative stress and neurotoxicity in Caenorhabditis elegans. via regulation of insulin/insulin-like growth factor signaling pathway[3].
Technical Parameters
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Species Human
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Source Sf9 insect cells
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Tag Tag Free
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Accession
Q96Q07 (S2-Q612)
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Gene ID114781
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Molecular Construction
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N-term
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BTBD9 (S2-Q612)
Accession # Q96Q07 -
C-term
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Protein Length
Full Length
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Synonyms
BTBD9; KIAA1880; BTB Domain Containing 9; BTB/POZ Domain-Containing Protein 9; DJ322I12.1; BTB (POZ) Domain Containing 9
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AA Sequence
SNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHRVILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLLDFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQEVLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMSLTELLNVVRPSGLLSPDAILDAIKVRSESRDMDLNYRGMLIPEENIATMKYGAQVVKGELKSALLDGDTQNYDLDHGFSRHPIDDDCRSGIEIKLGQPSIINHIRILLWDRDSRSYSYFIEVSMDELDWVRVIDHSQYLCRSWQKLYFPARVCRYIRIVGTHNTVNKIFHIVAFECMFTNKTFTLEKGLIVPMENVATIADCASVIEGVSRSRNALLNGDTKNYDWDSGYTCHQLGSGAIVVQLAQPYMIGSIRLLLWDCDDRSYSYYVEVSTNQQQWTMVADRTKVSCKSWQSVTFERQPASFIRIVGTHNTANEVFHCVHFECPEQQSSQKEENSEESGTGDTSLAGQQLDSHALRAPSGSSLPSSPGSNSRSPNRQHQ
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Purity
≥ 90%, as determined by reducing SDS-PAGE.
Product Properties
Solution.
<1 EU/μg, determined by LAL method.
Please use rapid thawing with running water to thaw the protein.
Stored at -80°C for 1 year from date of receipt. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
Shipping with dry ice.
Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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