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ISX-9 (Synonyms: Isoxazole 9)

Cat. No.: HY-12323 Purity: 98.01%
Handling Instructions

ISX-9 is a small molecule inducer of adult neural stem cell differentiation.

For research use only. We do not sell to patients.

ISX-9 Chemical Structure

ISX-9 Chemical Structure

CAS No. : 832115-62-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 99 In-stock
Estimated Time of Arrival: December 31
5 mg USD 90 In-stock
Estimated Time of Arrival: December 31
10 mg USD 132 In-stock
Estimated Time of Arrival: December 31
50 mg USD 300 In-stock
Estimated Time of Arrival: December 31
100 mg USD 540 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

    ISX-9 purchased from MCE. Usage Cited in: Patent. US20180273906A1.

    The western blots show that exosomes from iPSC and CPCISX-9 are enriched in Exosome (Exo)-specific markers Tsg101.
    • Biological Activity

    • Technical Information

    • Purity & Documentation

    • References

    Description

    ISX-9 is a small molecule inducer of adult neural stem cell differentiation. Target: At 2.5-20 μM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer factor 2-dependent gene expression.ISX-9 administered at 20 mg/kg for 12 days to mice has been reported to improve hippocampal function as evidenced by enhanced spatial memory ability in the Morris water maze test.

    Solvent & Solubility
    In Vitro: 

    DMSO : ≥ 37 mg/mL (157.94 mM)

    *"≥" means soluble, but saturation unknown.

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 4.2686 mL 21.3429 mL 42.6858 mL
    5 mM 0.8537 mL 4.2686 mL 8.5372 mL
    10 mM 0.4269 mL 2.1343 mL 4.2686 mL
    *Please refer to the solubility information to select the appropriate solvent.
    References
    Molecular Weight

    234.27

    Formula

    C₁₁H₁₀N₂O₂S

    CAS No.

    832115-62-5

    SMILES

    O=C(C1=NOC(C2=CC=CS2)=C1)NC3CC3

    Storage
    Powder -20°C 3 years
      4°C 2 years
    In solvent -80°C 6 months
      -20°C 1 month
    Shipping

    Room temperature in continental US; may vary elsewhere

    • Molarity Calculator

    • Dilution Calculator

    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

    Mass   Concentration   Volume   Molecular Weight *
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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2

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    Inquiry Information

    Product Name:
    ISX-9
    Cat. No.:
    HY-12323
    Quantity:

    ISX-9

    Cat. No.: HY-12323