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ISX-9 (Synonyms: Isoxazole 9)

Cat. No.: HY-12323 Purity: 98.01%
Handling Instructions

ISX-9 is a small molecule inducer of adult neural stem cell differentiation.

For research use only. We do not sell to patients.

ISX-9 Chemical Structure

ISX-9 Chemical Structure

CAS No. : 832115-62-5

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 99 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
5 mg USD 90 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
10 mg USD 132 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
50 mg USD 300 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
100 mg USD 540 In-stock
Stock in Sweden
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

ISX-9 is a small molecule inducer of adult neural stem cell differentiation. Target: At 2.5-20 μM, ISX-9 has been shown to dose-dependently trigger neurogenesis and block gliogenesis in adult rat hippocampal stem cells through a calcium-activated signaling pathway dependent on myocyte-enhancer factor 2-dependent gene expression.ISX-9 administered at 20 mg/kg for 12 days to mice has been reported to improve hippocampal function as evidenced by enhanced spatial memory ability in the Morris water maze test.

References
Preparing Stock Solutions
Concentration Volume Mass 1 mg 5 mg 10 mg
1 mM 4.2686 mL 21.3429 mL 42.6858 mL
5 mM 0.8537 mL 4.2686 mL 8.5372 mL
10 mM 0.4269 mL 2.1343 mL 4.2686 mL
Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

234.27

Formula

C₁₁H₁₀N₂O₂S

CAS No.

832115-62-5

SMILES

O=C(C1=NOC(C2=CC=CS2)=C1)NC3CC3

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 37 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
ISX-9
Cat. No.:
HY-12323
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