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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
110 Results for "
Protein Z
" in MedChemExpress (MCE) Product Catalog:
Products (110)
110 Results for "Protein Z" in MCE Product Catalog:
819
Research Areas:
Z-VAD-FMK is a pan-caspase inhibitor and also an ICE-like protease inhibitor, which inhibits apoptosis by preventing the processing of CPP32 to its active form. Z-VAD-FMK sensitivity varies primarily due to differential expression of receptor-interacting protein 1 (RIP1). Z-VAD-FMK limits the cryopreservation-induced apoptosis by reducing caspase-3 activity of in vitro produced bovine embryos. Z-VAD-FMK is immunosuppressive in vitro and inhibits T cell proliferation without blocking the processing of caspase-8 and caspase-3. Z-VAD-FMK leads to a decrease in intracellular glutathione (GSH) with a concomitant increase in reactive oxygen species (ROS) levels in activated T cells. Z-VAD-FMK is due to oxidative stress via the depletion of GSH. Z-VAD-FMK can be used for the study of acute pancreatitis .
22
22 Cited Publications
Synonyms: Z/E-Guggulsterone
9
9 Cited Publications
(E/Z)-Mirin is a mixture of (E)-Mirin and Mirin ((Z)-Mirin) (HY-19959) configurations. Among them, Mirin is an inhibitor of MRN (Mre11-Rad50-Nbs1). Mirin prevents MRN-dependent ATM activation without affecting ATM protein kinase activity .
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2
Target:
Research Areas:
UCM05 (G28UCM) is a fatty acid synthase (FASN) and filamentous temperature-sensitive protein Z (Ftsz) inhibitor. UCM05 inhibits fatty acid synthesis, viral replication, and Gram-positive bacterial growth. UCM05 binds to FtsZ GTP-binding sites, inhibits GTPase activity, and disrupts Z-ring localization. UCM05 can be used for the research of HSV-1/2 infection, HIV-1 infection, and Gram-positive bacterial infections[1][2][3].
2
2 Cited Publications
Cat. No.: HY-P71436
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ZBP1; Z‑DNA Binding Protein 1; alias:C20orf183; DLM1; DAI; Tumor Stroma And Activated Macrophage Protein DLM‑1; Z‑DNA‑Binding Protein 1; DLM‑1; DNA‑Dependent Activator Of IRFs; DJ718J7.3; DNA‑Dependent Activator Of IFN‑Regulatory Factors; Chromosome 20 Op
2
2 Cited Publications
Cat. No.: HY-P70455
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: IL37; IL1RP1; Prev. IL1F7; IL-37; IL-1RP1; IL1H4; IL-1H4; Interleukin 1 Family, Member 7 (Zeta); IL-1F7; IL1F7 (Canonical Product IL-1F7b); FIL1Z; IL-1F7b (IL-1H4, IL-1H, IL-1RP1); Interleukin-1-Related Protein; Interleukin 1 Family Member 7; Interleukin-
1
1 Cited Publications
Synonyms: trans-10,cis-12 CLA2
Research Areas:
(10E,12Z)-Octadeca-10,12-dienoic acid (trans-10,cis-12 CLA2) is an orally active PPARα activator and inhibits adipocyte differentiation. (10E,12Z)-Octadeca-10,12-dienoic acid and its downstream metabolites have various antioxidant and antitumor activities. (10E,12Z)-Octadeca-10,12-dienoic acid can induce proinflammatory cytokines and chemokines, which would lead to decreased adipogenesis and insulin resistance in adipose tissue. (10E,12Z)-Octadeca-10,12-dienoic acid can affect many aspects of milk fat synthesis. (10E,12Z)-Octadeca-10,12-dienoic acid reduces expression of lipogenic enzymes and inhibits the desaturation of fatty acids. (10E,12Z)-Octadeca-10,12-dienoic acid can reduce lipoprotein lipase (LPL) activity in cultured 3T3-L1 adipocytes and enhance triacylglycerol release from these cells. (10E,12Z)-Octadeca-10,12-dienoic acid decreases the expression of hepatic stearoyl-CoA desatyrase mRNA in mice. (10E,12Z)-Octadeca-10,12-dienoic acid is associated with changes in mucosal NF-κB and Cyclin D1 protein levels in mice .
1
1 Cited Publications
Cat. No.: HY-P0021A
CAS No.: 108963-70-8
Synonyms: Spectrozyme PCa; Chromozym Pca diacetate
Target:
Research Areas:
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1
1
1
1 Cited Publications
Cat. No.: HY-P7758
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: CTSZ; Cathepsin IV; Cathepsin Z; Cathepsin B2; Cathepsin X; Cathepsin Z1; CTSX; Cathepsin Y; Cysteine-Type Carboxypeptidase; Cathepsin P; Lysosomal Carboxypeptidase B; Preprocathepsin P; Carboxypeptidase LB
1
Cat. No.: HY-178842
CAS No.: 3077480-59-9
Target:
Research Areas:
Z52 is a Ras protein inhibitor. Z52 can be used for the research of cancer, such as pancreatic cancer .
Cat. No.: HY-113037
CAS No.: 13058-04-3
Synonyms: (E/Z)-Farnesyl diphosphate
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Endogenous metabolite Disease Research Fields
Target:
Cat. No.: HY-P1407
Cat. No.: HY-W102456
CAS No.: 122555-04-8
Synonyms: L-4-Acetylphenylalanine
Target:
Research Areas:
H-Phe(4-Ac)-OH (L-4-Acetylphenylalanine) is a keto-amino acid that can be converted from α-keto acids containing an acetyl group. H-Phe(4-Ac)-OH can be added to the amber position to form mutant Z-domain proteins. H-Phe(4-Ac)-OH is used as a functional amino acid in peptide modification to achieve chemical bonding between peptides and solid surfaces .
(E/Z)-E64FC26 is a mixture complex of E-E64FC26 and Z-E64FC26. E64FC26 (E-E64FC26) is a potent pan-inhibitor of the protein disulfide isomerase (PDI) family, with IC50s of 1.9, 20.9, 25.9, 16.3, and 25.4 μM against PDIA1, PDIA3, PDIA4, TXNDC5, and PDIA6. E64FC26 shows anti-myeloma activity .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
