1. MAPK/ERK Pathway
  2. Raf
  3. (Z)-GW 5074

(Z)-GW 5074 

Cat. No.: HY-10542A
Handling Instructions

(Z)-GW 5074 is a compound which interacts with both mHTT (mutant huntingtin protein) and LC3, but not but not with the wild-type HTT protein. (Z)-GW 5074 inhibits c-Raf, shows no effect on autophagy, and is effective for neurodegenerative disorder.

For research use only. We do not sell to patients.

(Z)-GW 5074 Chemical Structure

(Z)-GW 5074 Chemical Structure

CAS No. : 1233748-60-1

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Description

(Z)-GW 5074 is a compound which interacts with both mHTT (mutant huntingtin protein) and LC3, but not but not with the wild-type HTT protein. (Z)-GW 5074 inhibits c-Raf, shows no effect on autophagy, and is effective for neurodegenerative disorder[1].

IC50 & Target[1]

c-Raf

 

Molecular Weight

520.94

Formula

C₁₅H₈Br₂INO₂

CAS No.

1233748-60-1

SMILES

O=C1NC2=C(C=C(I)C=C2)/C1=C/C3=CC(Br)=C(O)C(Br)=C3.[Z]

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

(Z)-GW 5074RafRaf kinasesInhibitorinhibitorinhibit

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