TLT8
TLT8 is a ByeTAC protein degrader targeting BTK. TLT8 non-covalently binds to Rpn-13 and BTK, thereby inducing BTK degradation. TLT8 can be used in chronic lymphocytic leukemia research. (Rpn-13 ligand: HY-159808; BTK ligand: HY-Z3101; linker: HY-172823).
For research use only. We do not sell to patients.
- Formula: C63H76BrClN12O12S
- Molecular Weight:1340.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Chemical Information
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Molecular Weight 1340.77
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Formula C63H76BrClN12O12S
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SMILES
NC1=C2C(C3=CC=C(C=C3)OC4=CC=CC=C4)=NN(C2=NC=N1)[C@H]5CCCN(C5)C(CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CC6SC7=NN=C(N7N=C6C8=CC=C(C=C8)Cl)CC9=CC=C(C=C9)Br)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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