PDI-IN-5
PDI-IN-5 (compound 30z) is an allosteric-covalent inhibitor targeting protein disulfide isomerase (PDI) with a 2-chloro-pyrrolopyrimidin-4-one scaffold, with an IC50 of 0.4 μM. PDI-IN-5 exhibits selectivity for ERp57 and GPX4, and inhibits glioblastoma. PDI-IN-5 can be used in glioblastoma-related research.
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- CAS No.: 3097563-91-9
- Formule: C19H16Cl2N4O2
- Masse moléculaire:403.26
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
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GPX4 |
Chemical Information
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CAS No. 3097563-91-9
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Masse moléculaire 403.26
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Formule C19H16Cl2N4O2
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SMILES
O=C(N1CC#CC(NCC)=O)C2=C(N=C1Cl)N(CC3=C(C=CC=C3)Cl)C=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PDI-IN-5 Related Classifications
HY-181574 Related Classifications
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