H-Phe(4-Ac)-OH
Based on 1 Customer Validation
H-Phe(4-Ac)-OH (L-4-Acetylphenylalanine) is a keto-amino acid that can be converted from α-keto acids containing an acetyl group. H-Phe(4-Ac)-OH can be added to the amber position to form mutant Z-domain proteins. H-Phe(4-Ac)-OH is used as a functional amino acid in peptide modification to achieve chemical bonding between peptides and solid surfaces.
For research use only. We do not sell to patients.
- Purity: 99.19%
- CAS No.: 122555-04-8
- Formula: C11H13NO3
- Molecular Weight:207.23
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 122555-04-8
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Appearance Solid
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Molecular Weight 207.23
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Formula C11H13NO3
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Color Off-white to light yellow
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SMILES
CC(=O)C1=CC=C(C=C1)C[C@@H](C(=O)O)N
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Synonyms
L-4-Acetylphenylalanine
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 5 mg/mL (24.13 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Tang H, et al. Recent Technologies for Genetic Code Expansion and their Implications on Synthetic Biology Applications. J Mol Biol. 2022 Apr 30;434(8):167382. [Content Brief]
[2]. Volkwein W, et al. A Versatile Toolbox for the Control of Protein Levels Using Nε-Acetyl-l-lysine Dependent Amber Suppression. ACS Synth Biol. 2017 Oct 20;6(10):1892-1902. [Content Brief]
[3]. Liu H, Wang L, Brock A, Wong CH, Schultz PG. A method for the generation of glycoprotein mimetics. J Am Chem Soc. 2003 Feb 19;125(7):1702-3. [Content Brief]
[4]. Zhao Y, et al. A fluorescent amino acid probe to monitor efficiency of peptide conjugation to glass surfaces for high density microarrays. Mol Biosyst. 2012 Mar;8(3):879-87. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 4.8256 mL | 24.1278 mL | 48.2556 mL | 120.6389 mL |
| 5 mM | 0.9651 mL | 4.8256 mL | 9.6511 mL | 24.1278 mL | |
| 10 mM | 0.4826 mL | 2.4128 mL | 4.8256 mL | 12.0639 mL | |
| 15 mM | 0.3217 mL | 1.6085 mL | 3.2170 mL | 8.0426 mL | |
| 20 mM | 0.2413 mL | 1.2064 mL | 2.4128 mL | 6.0319 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.