122555-04-8
122555-04-8
Chemical Structure
H-Phe(4-Ac)-OH
Synonym(s): L-4-Acetylphenylalanine
- CAS No.: 122555-04-8
- Formula:C11H13NO3
- Molecular Weight:207.23
IUPAC Name: (S)-3-(4-acetylphenyl)-2-aminopropanoic acid
InChIKey: ZXSBHXZKWRIEIA-JTQLQIEISA-N
SMILES: CC(=O)C1=CC=C(C=C1)C[C@@H](C(=O)O)N
Biological Activity: H-Phe(4-Ac)-OH (L-4-Acetylphenylalanine) is a keto-amino acid that can be converted from α-keto acids containing an acetyl group. H-Phe(4-Ac)-OH can be added to the amber position to form mutant Z-domain proteins. H-Phe(4-Ac)-OH is used as a functional amino acid in peptide modification to achieve chemical bonding between peptides and solid surfaces[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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H-Phe(4-Ac)-OH | 99.19% | H-Phe(4-Ac)-OH (L-4-Acetylphenylalanine) is a keto-amino acid that can be converted from α-keto acids containing an acetyl group. H-Phe(4-Ac)-OH can be added to the amber position to form mutant Z-domain proteins. H-Phe(4-Ac)-OH is used as a functional amino acid in peptide modification to achieve chemical bonding between peptides and solid surfaces. | ||||||||||||||||||||
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References
- [1]. Tang H, et al. Recent Technologies for Genetic Code Expansion and their Implications on Synthetic Biology Applications. J Mol Biol. 2022 Apr 30;434(8):167382. [Content Brief]
- [2]. Volkwein W, et al. A Versatile Toolbox for the Control of Protein Levels Using Nε-Acetyl-l-lysine Dependent Amber Suppression. ACS Synth Biol. 2017 Oct 20;6(10):1892-1902. [Content Brief]
- [3]. Liu H, Wang L, Brock A, Wong CH, Schultz PG. A method for the generation of glycoprotein mimetics. J Am Chem Soc. 2003 Feb 19;125(7):1702-3. [Content Brief]
- [4]. Zhao Y, et al. A fluorescent amino acid probe to monitor efficiency of peptide conjugation to glass surfaces for high density microarrays. Mol Biosyst. 2012 Mar;8(3):879-87. [Content Brief]
