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Results for "

piperazines

" in MedChemExpress (MCE) Product Catalog:

By Targets:	5-HT Receptor (5) ADC Linker (1) Adenosine Receptor (1) Adenylate Cyclase (1) Adrenergic Receptor (1) Anaplastic lymphoma kinase (ALK) (1) Androgen Receptor (2) Antibiotic (3) Apolipoprotein (1) Apoptosis (34) Autophagy (27) Bacterial (8) Bcl-2 Family (3) Biochemical Assay Reagents (22) Btk (2) Calcium Channel (3) Caspase (1) DNA Alkylator/Crosslinker (2) DNA/RNA Synthesis (3) Dopamine Receptor (1) Drug Derivative (19) Drug Intermediate (26) Drug-Linker Conjugates for ADC (1) E1/E2/E3 Enzyme (1) E3 Ligase Ligand-Linker Conjugates (79) Endogenous Metabolite (4) Epigenetic Reader Domain (3) Epoxide Hydrolase (1) Estrogen Receptor/ERR (1) Ferroptosis (3) Filovirus (1) Fluorescent Dye (2) Fungal (3) FXR (1) GABA Receptor (4) Glutathione Peroxidase (1) HBV (1) Histamine Receptor (9) HIV (1) Influenza Virus (1) Isotope-Labeled Compounds (23) Itk (1) Lactate Dehydrogenase (1) LDLR (1) Ligands for E3 Ligase (10) Ligands for Target Protein for PROTAC (1) Liposome (2) mGluR (1) MOFs (3) Necroptosis (1) Opioid Receptor (1) Parasite (7) PARP (1) Penicillin-binding protein (PBP) (1) Phosphodiesterase (PDE) (1) PROTAC Linkers (66) PROTACs (11) Protein Arginine Deiminase (1) Reactive Oxygen Species (ROS) (1) Reference Standards (13) Serotonin Transporter (1) Sodium Channel (1) Somatostatin Receptor (1) Target Protein Ligand-Linker Conjugates (3) Trk Receptor (1) TRP Channel (1) Urease (1)
By Research Areas:	Cancer (179) Cardiovascular Disease (6) Endocrinology (2) Infection (24) Inflammation/Immunology (9) Metabolic Disease (6) Neurological Disease (43)
Click Chemistry:	Alkynes (2)
Oligonucleotides:	Cationic Lipids (2)

326

Inhibitors & Agonists

Biochemical Assay Reagents

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Isotope-Labeled Compounds

Click Chemistry

Oligonucleotides

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0349

Meclizine dihydrochloride 4 Publications Verification Meclozine dihydrochloride	Histamine Receptor Apoptosis	Neurological Disease Endocrinology Cancer
Meclizine (Meclozine) dihydrochloride, an antihistamine, reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine dihydrochloride is a member of the piperazine class of H1 antagonists. Meclizine dihydrochloride is an effective anti-motion sickness agent. Meclizine dihydrochloride crosses the blood-brain barrier. Meclizine dihydrochloride can be used for the research of polyQ toxicity disorders, such as Huntington's disease. Meclizine dihydrochloride is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR .

HY-44432

Navitoclax-piperazine ABT-263-piperazine	Ligands for Target Protein for PROTAC Bcl-2 Family	Cancer
Navitoclax-piperazine (ABT-263-piperazine) is a Navitoclax (HY-10087) analog and BCL-XL inhibitor. Navitoclax-piperazine is the ligand for target protein of PROTAC DT2216 (HY-130604). Navitodax-pperaie and E3 ubiquitin ligase VHL ligand can be used to synthesize PROTAC DT2216 (HY-130604) .

HY-W002603

*Benzyl piperazine-1-carboxylate*	Biochemical Assay Reagents Drug Intermediate	Neurological Disease
Benzyl piperazine-1-carboxylate is a synthetic intermediate that can be used in the research of melanocortin-4 (MC4) receptor antagonists .

HY-W454945S

*tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8* N-Boc-piperazine-d₈	Isotope-Labeled Compounds	Others
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled tert-Butyl piperazine-1-carboxylate .

HY-174304

*Bis(vinylsulfonyl)piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide*	Drug-Linker Conjugates for ADC	Cancer
Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide is a drug-linker conjugates for ADC. Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide consists of Triptolide (HY-32735) and a stable cleavable linker (Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-Cl) (HY-174810). Bis (vinylsulfonyl) piperazine-triazole-PEG3-O-diisopropylsilyl-triptolide can be used for the synthesis of antibody-drug conjugates (ADCs) .

HY-17599

Piperazine citrate 1 Publications Verification 1,4-Diazacyclohexane citrate	GABA Receptor Parasite	Infection
Piperazine (1,4-Diazacyclohexane) citrate is a gamma-aminobutyric acid (GABA) agonist . Piperazine citrate is a vital building block and is an essential core in numerous marketed agents with diverse pharmacological activities .

HY-W259932

*Lenalidomide 5'-piperazine* hydrochloride**	Ligands for E3 Ligase	Cancer
Lenalidomide 5'-piperazine hydrochloride can serve as a Cereblon ligand to recruit CRBN protein. Lenalidomide 5'-piperazine hydrochloride can be linked to target protein ligands via a linker to form PROTAC molecules, such as KI-CDK9d-32 (HY-173523) .

HY-100887

Piperazine Erastin Maximum Cited Publications 9 Publications Verification	Ferroptosis	Cancer
Piperazine erastin is an analog of erastin which induces an iron-dependent form of non-apoptotic cell death, termed ferroptosis. Piperazine erastin can be used in cancer research .

HY-130837

JH-LPH-28	Bacterial	Infection
JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL .

HY-W011726

*1-(4-Methoxyphenyl)piperazine* hydrochloride** Piperazine, 1- (4-methoxyphenyl)-, dihydrochloride	Drug Derivative	Neurological Disease
1-(4-Methoxyphenyl)piperazine (Piperazine, 1- (4-methoxyphenyl)-) hydrochloride is a piperazine derivative with neural activity .

HY-40041

(R)-1-Boc-3-methyl-piperazine	Biochemical Assay Reagents Drug Intermediate	Cancer
(R)-1-Boc-3-methyl-piperazine (Compound I3-1) is a chemical intermediate. (R)-1-Boc-3-methyl-piperazine can be used for the preparation of Compound I3. Compound I3 exhibits anticancer activity against colorectal adenocarcinoma with BRCA2 gene deletion .

HY-130838

JH-LPH-33	Bacterial	Infection
JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL .

HY-40040

(S)-1-Boc-3-methylpiperazine	Drug Intermediate	Infection
(S)-1-Boc-3-methylpiperazine is a synthetic intermediate for indole-piperazine hybrid antimicrobial agent preparation. (S)-1-Boc-3-methylpiperazine can be used for research on bacterial infection and fungal infection .

HY-160244

*Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride*	Ligands for E3 Ligase	Cancer
Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride is the Pomalidomide (HY-10984)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC.

HY-Y0889A

*1-(2,3-Dichlorphenyl)piperazine* hydrochloride**	Endogenous Metabolite	Metabolic Disease
1-(2,3-Dichlorphenyl)piperazine hydrochloride is a potent DHCR7 inhibitor with the activity of inhibiting cholesterol biosynthesis. 1-(2,3-Dichlorphenyl)piperazine hydrochloride is often used in biological research to evaluate the function of cholesterol biosynthesis pathway. The application of 1-(2,3-Dichlorphenyl)piperazine hydrochloride is of great significance for understanding diseases related to cholesterol biosynthesis .

HY-157566

*Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride*	Ligands for E3 Ligase	Cancer
Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride is a functionalized cerebellar ligand for PROTAC development, combining E3 ligand and terminal piperidine for subsequent chemical reactions. A protein degradant with a rigid connector is generated .

HY-W008813

1-(3-Methoxyphenyl)piperazine	Biochemical Assay Reagents	Others
1-(3-Methoxyphenyl)piperazine (Compound 4) is an analytical reference standard categorized as a piperazine .

HY-130836

LpxH-IN-AZ1 1 Publications Verification	Bacterial	Infection
LpxH-IN-AZ1, a sulfonyl piperazine compound, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. LpxH-IN-AZ1 is a potent inhibitor of Klebsiella pneumoniae LpxH with IC₅₀ of 0.36 μM .

HY-B1505A

Acefylline piperazine Theophyllineacetic acid piperazine; Theophylline-7-acetic acid piperazine	Adenosine Receptor Protein Arginine Deiminase Phosphodiesterase (PDE)	Cardiovascular Disease Neurological Disease Inflammation/Immunology
Acefylline (Theophyllineacetic acid) piperazine, a xanthine derivative, is an Adenosine Receptor antagonist. Acefylline piperazine is a peptidylarginine deiminase (PAD) activator. Acefylline piperazine is also a bronchodilator and cardiac stimulant that inhibits rat lung cAMP phosphodiesterase isoenzymes. Acefylline piperazine can be used in asthma research .

HY-W004440

*2,2'-Piperazine-1,4-diyldiethanamine*	Biochemical Assay Reagents	Others
2,2'-(Piperazine-1,4-diyl)diethanamine is a piperazine with two N-ethanamine groups. This type of molecule may be used to build drug molecules or design novel ionizable aminolipid head groups for lipid nanoparticles.

HY-138783A

*Thalidomide-Piperazine-Piperidine hydrochloride*	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-Piperazine-Piperidine hydrochloride is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-Piperazine-Piperidine hydrochloride incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology .

HY-Y0889

1-(2,3-Dichlorphenyl)piperazine	Endogenous Metabolite	Metabolic Disease
1-(2,3-Dichlorphenyl)piperazine is a potent DHCR7 inhibitor with the activity of inhibiting cholesterol biosynthesis. 1-(2,3-Dichlorphenyl)piperazine is often used in biological research to evaluate the function of cholesterol biosynthesis pathway. The application of 1-(2,3-Dichlorphenyl)piperazine is of great significance for understanding diseases related to cholesterol biosynthesis .

HY-B0349A

Meclizine Meclozine	Histamine Receptor Apoptosis	Neurological Disease Inflammation/Immunology
Meclizine (Meclozine), an antihistamine, reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine is a member of the piperazine class of H1 antagonists. Meclizine is an effective anti-motion sickness agent. Meclizine crosses the blood–brain barrier. Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR. Meclizine can be used for the research of polyQ toxicity disorders, such as Huntington's disease .

HY-66010

Cinepazide Maleate MD-67350	Calcium Channel	Cardiovascular Disease
Cinepazide Maleate (MD-67350) is a piperazine derivative and acts as a weak calcium channel blocker. Cinepazide Maleate is a potent vasodilator and can be used for the research of cerebrovascular diseases, including ischemic stroke, brain?infarct et. al .

HY-78871S

1-(Methyl-d3)piperazine	Isotope-Labeled Compounds	Others
1-(Methyl-d₃)piperazine is the deuterium labeled N-Methylpiperazine .

HY-W016777

*2,2'-Piperazine-1,4-diyldiethanol*	PROTAC Linkers	Cancer
2,2'-(Piperazine-1,4-diyl)diethanol is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-W797383

Phthalimidinoglutarimide-6-piperazine	E3 Ligase Ligand-Linker Conjugates	Cancer
Phthalimidinoglutarimide-6-piperazine is a conjugate of E3 ubiquitin ligase ligand-Linker, which can be used to synthesize complete PROTACs molecules.

HY-176063

TRPV1 antagonist 11	TRP Channel Opioid Receptor	Neurological Disease
TRPV1 antagonist 11 (compound 2ac) is a potent TRPV1 antagonist with an IC₅₀ of 29.3 nM. TRPV1 antagonist 11 is a potent μ-opioid receptor (MOR) agonist with a K_i of 60.3 nM. TRPV1 antagonist 11, a pyrimidine piperazine, exhibits pain relieving effects by antagonizing TRPV1 and stimulating MOR. TRPV1 antagonist 11 shows a potent, dose-dependent anti-nociceptive effect in a Formalin-induced pain model in mice .

HY-W040491

*1-(4-Bromophenyl)piperazine* hydrochloride** 4-(4-bromophenyl)piperazin-1-ium chloride	Drug Derivative	Neurological Disease
1-(4-Bromophenyl)piperazine hydrochloride (4-(4-bromophenyl)piperazin-1-ium chloride) is a piperazine.

HY-178512

**Piperazine-CO-C1-Azacyclohexane-C1-Piperazine**	PROTAC Linkers	Cancer
Piperazine-CO-C1-Azacyclohexane-C1-Piperazine is a PROTAC linker can be used in the synthesis of PROTACs, such as PROTAC CDK4/6/9 degrader 1 (HY-178452) .

HY-178518

Thalidomide-C1-O-CO-C2-Piperazine-CO-C1-Azacyclohexane-C1-Piperazine	E3 Ligase Ligand-Linker Conjugates E1/E2/E3 Enzyme	Cancer
Thalidomide-C1-O-CO-C2-Piperazine-CO-C1-Azacyclohexane-C1-Piperazine is an E3 ligase ligand-linker conjugate containing a cereblon (CRBN) ligand for E3 ubiquitin ligase and a linker. Thalidomide-C1-O-CO-C2-Piperazine-CO-C1-Azacyclohexane-C1-Piperazine can be used to synthesize PROTAC CDK4/6/9 degrader 2 (HY-178516) .

HY-W460315

*3,3'-Piperazine-1,4-diyldipropanoic acid*	PROTAC Linkers	Cancer
3,3'-(Piperazine-1,4-diyl)dipropanoic acid is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-20797S

*1-BOC-4-(2-Hydroxyethyl)piperazine-d4*	Isotope-Labeled Compounds	Others
1-BOC-4-(2-Hydroxyethyl)piperazine-d₄ is the deuterium labeled 1-BOC-4-(2-Hydroxyethyl)piperazine[1].

HY-W009681

*1-(2-Methoxyphenyl)piperazine* hydrochloride**	5-HT Receptor Serotonin Transporter Drug Intermediate	Infection Neurological Disease
1-(2-Methoxyphenyl)piperazine hydrochloride is a key agent intermediate of antipsychotics with high affinity to the serotonin receptors and 5-HT, which can be used to synthesize the intestinal worm-repellent agents Piperazine phosphate (HY-B0912C) and Piperazine citrate (HY-17599), as well as Fluphenazine (HY-119980), dihydrochloride, Rifampicin (HY-B0272) .

HY-W262798

1-(Piperidin-4-ylmethyl)piperazine PMP	PROTAC Linkers	Cancer
1-(Piperidin-4-ylmethyl)piperazine is a PROTAC linker. 1-(Piperidin-4-ylmethyl)piperazine can be used to design PROTAC, such as PROTAC EGFR degrader 13 (HY-158313) .

HY-120220

Piposulfan A-20968; Ancyte	DNA/RNA Synthesis	Cancer
Piposulfan (Ancyte) is a methanesulfonate, alkylating derivative of piperazine. Piposulfan has potential antineoplastic activity. Piposulfan can be used for the research of cancer .

HY-125705

Herquline A Herqueline A	Influenza Virus	Infection Cardiovascular Disease
Herquline A (Herqueline A) is a fungal piperazine alkaloid. Herquline A is a fungal metabolite that inhibits platelet aggregation and replication of the influenza virus .

HY-66010A

Cinepazide	Calcium Channel	Cardiovascular Disease
Cinepazide is a piperazine derivative and acts as a weak calcium channel blocker. Cinepazide is a potent vasodilator and can be used for the research of cerebrovascular diseases, including ischemic stroke, brain infarct et. al .

HY-B0349B

Meclizine dihydrochloride monohydrate Meclozine dihydrochloride monohydrate	Histamine Receptor Apoptosis	Neurological Disease Inflammation/Immunology
Meclizine (Meclozine) dihydrochloride monohydrate, an antihistamine, reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine dihydrochloride is a member of the piperazine class of H1 antagonists. Meclizine dihydrochloride monohydrate is an effective anti-motion sickness agent. Meclizine dihydrochloride monohydrate crosses the blood-brain barrier. Meclizine dihydrochloride monohydrate is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR. Meclizine dihydrochloride monohydrate can be used for the research of polyQ toxicity disorders, such as Huntington's disease .

HY-B0349R

Meclizine dihydrochloride (Standard) Meclozine dihydrochloride (Standard)	Reference Standards Histamine Receptor Apoptosis	Neurological Disease Endocrinology Cancer
Meclizine (dihydrochloride) (Standard) is the analytical standard of Meclizine (dihydrochloride). This product is intended for research and analytical applications. Meclizine (Meclozine) dihydrochloride, an antihistamine, reversibly inhibits the interaction of histamine at the H1 receptors. Meclizine dihydrochloride is a member of the piperazine class of H1 antagonists. Meclizine dihydrochloride is an effective anti-motion sickness agent. Meclizine dihydrochloride crosses the blood-brain barrier. Meclizine dihydrochloride can be used for the research of polyQ toxicity disorders, such as Huntington's disease. Meclizine dihydrochloride is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR .

HY-130838R

JH-LPH-33 (Standard)	Antibiotic Reference Standards Bacterial	Infection
JH-LPH-33 (Standard) is the analytical standard of JH-LPH-33. This product is intended for research and analytical applications. JH-LPH-33, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-33 displays outstanding antibiotic activity with a MIC value of 0.66 μg/mL[1].

HY-130837R

JH-LPH-28 (Standard)	Antibiotic Reference Standards Bacterial	Infection
JH-LPH-28 (Standard) is the analytical standard of JH-LPH-28. This product is intended for research and analytical applications. JH-LPH-28, a sulfonyl piperazine analog, is a potent UDP-2,3-diacylglucosamine pyrophosphate hydrolase LpxH inhibitor. JH-LPH-28 displays outstanding antibiotic activity with a MIC value of 0.83 μg/mL[1].

HY-W797383A

(S)-Phthalimidinoglutarimide-6-piperazine	E3 Ligase Ligand-Linker Conjugates	Cancer
(S)-Phthalimidinoglutarimide-6-piperazine is the (S)-configuration of Phthalimidinoglutarimide-6-piperazine (HY-W797383). (S)-Phthalimidinoglutarimide-6-piperazine is an E3 ligase ligand-linker conjugate. (S)-Phthalimidinoglutarimide-6-piperazine can be used for synthesis of PROTAC SMARCA2 degrader-35 (HY-176871) .

HY-178515

Thalidomide-piperazine-CO-C-azacyclohexane-C1-piperazine	E3 Ligase Ligand-Linker Conjugates	Cancer
Thalidomide-piperazine-CO-C-azacyclohexane-C1-piperazine is a synthesized E3 ligase ligand-linker conjugate. Thalidomide-piperazine-CO-C-azacyclohexane-C1-piperazine can be used for synthesizing PROTAC CDK4/6/9 degrader 1 (HY-178452) .

HY-W834174

Thalidomide-5-piperazine	Ligands for E3 Ligase	Cancer
Thalidomide-5-piperazine is a Ligand for target protein for pROTAC.

HY-W578976S

*N-Boc-piperazine-d4*	Isotope-Labeled Compounds	Others
N-Boc-piperazine-d₄ is the deuterium labeled N-Boc-piperazine.

HY-B2186R

Piperazine adipate (Standard)	Reference Standards Parasite	Infection
Piperazine adipate (Standard) is the analytical standard of Piperazine adipate. This product is intended for research and analytical applications. Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.

HY-163233

Lenalidomide 5'-piperazine	Ligands for E3 Ligase	Cancer
Lenalidomide 5'-piperazine can serve as a Cereblon ligand to recruit CRBN protein. Lenalidomide 5'-piperazine can be linked to target protein ligands via a linker to form PROTAC molecules, such as KI-CDK9d-32 (HY-173523) .

HY-17599R

Piperazine citrate (Standard) 1,4-Diazacyclohexane citrate (Standard)	GABA Receptor Parasite Reference Standards	Infection
Piperazine (citrate) (Standard) is the analytical standard of Piperazine (citrate). This product is intended for research and analytical applications. Piperazine (1,4-Diazacyclohexane) citrate is a gamma-aminobutyric acid (GABA) agonist . Piperazine citrate is a vital building block and is an essential core in numerous marketed agents with diverse pharmacological activities .

HY-161201

*Thalidomide-piperazine-pyrimidine-piperazine-C-boc*	E3 Ligase Ligand-Linker Conjugates Autophagy Apoptosis	Cancer
Thalidomide-piperazine-pyrimidine-piperazine-C-boc is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide (HY-14658) and the corresponding Linker. Thalidomide-piperazine-pyrimidine-piperazine-C-boc can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.

Cat. No.	Product Name	Type

HY-W002603

*Benzyl piperazine-1-carboxylate*	Biochemical Assay Reagents
Benzyl piperazine-1-carboxylate is a synthetic intermediate that can be used in the research of melanocortin-4 (MC4) receptor antagonists .

HY-20128

Piperazin-2-one	Biochemical Assay Reagents
Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds .

HY-W001990

2-Piperazinopyridine 1-(Pyridin-2-yl)piperazine	Biochemical Assay Reagents
1-(2-Pyridyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-40041

(R)-1-Boc-3-methyl-piperazine	Biochemical Assay Reagents
(R)-1-Boc-3-methyl-piperazine (Compound I3-1) is a chemical intermediate. (R)-1-Boc-3-methyl-piperazine can be used for the preparation of Compound I3. Compound I3 exhibits anticancer activity against colorectal adenocarcinoma with BRCA2 gene deletion .

HY-40040

(S)-1-Boc-3-methylpiperazine	Biochemical Assay Reagents
(S)-1-Boc-3-methylpiperazine is a synthetic intermediate for indole-piperazine hybrid antimicrobial agent preparation. (S)-1-Boc-3-methylpiperazine can be used for research on bacterial infection and fungal infection .

HY-W054259

BFMO N,N'-Difurfuryloxamide; N1,N2-Bis(furan-2-ylmethyl)oxalamide	Biochemical Assay Reagents
BFMO (N,N'-Difurfuryloxamide) is an oxamide derivative and a bidentate ligand. BFMO exhibits plant growth regulatory activity and root growth inhibitory activity. BFMO can promote the copper-catalyzed N-arylation reaction between aniline compounds and cyclic secondary amines, realizing the coupling of (hetero) aryl bromides with (hetero) aryl amines and cyclic secondary amines .

HY-W001978

1-(4-Chlorobenzhydryl)piperazine	Biochemical Assay Reagents
1-(4-Chlorobenzhydryl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-41939

1-(2-Hydroxyethyl)piperazine	Biochemical Assay Reagents
1-(2-Hydroxyethyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W008865

PIPES sesquisodium	Biochemical Assay Reagents
PIPES sesquisodium is a pH buffer. PIPES refers to Piperazine N-N’-bis [2 ethanol sulphonic acid, an organic based buffer. PIPES can be used in the preparation of a variety of marine and mammalian tissues for electron microscopic study, with pH range of 6.1-7.5 .

HY-157920

Biotin-PE-maleimide N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine	Biochemical Assay Reagents
Biotin-PE-maleimide (N-Biotinyl-N'-[2-(N-maleimido)ethyl]piperazine) is a bulky, membrane-impermeable, sulfhydryl-containing reagent with a relatively large molecular size. Biotin-PE-maleimide can be used for biotin labeling (such as thiol groups) and detection of proteins or other biomolecules .

HY-W414406

CABS	Biochemical Assay Reagents
CABS is a zwitterionic piperazine buffer reagent, which can be used as a buffer reagent for wetting agents, pesticide emulsifiers, and dispersants, and has been used in fluorescent dyeing applications .

HY-148830

Piperazine-bis(ethyl octadeca-9,12-dienoate)	Biochemical Assay Reagents
Piperazine-bis(ethyl octadeca-9,12-dienoate) is a cationic lipid extracted from patent WO2023036148A1, and can be used for the generation of Lipid nanoparticles (LNPs).

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-125705

Herquline A Herqueline A	Cardiovascular Disease Alkaloids Microorganisms Classification of Application Fields Disease Research Fields Source Classification	Influenza Virus
Herquline A (Herqueline A) is a fungal piperazine alkaloid. Herquline A is a fungal metabolite that inhibits platelet aggregation and replication of the influenza virus .

HY-W438378

4-Hydroxy-3-methoxyphenylglycol piperazine HMPG piperazine	Monophenols Phenols Endogenous metabolite Source Classification	Biochemical Assay Reagents
4-Hydroxy-3-methoxyphenylglycol piperazine (HMPG piperazine) is a salt of HMPG combined with piperazine. HMPG is a metabolite of adrenaline and norepinephrine and is an important marker of catecholamine hormone metabolism in the body. 4-Hydroxy-3-methoxyphenylglycol piperazine is used as a standard in clinical laboratories to accurately measure the HMPG content in urine .

HY-N19180

Hancockiamide C	Structural Classification Alkaloids Piperidine Alkaloids Microorganisms Source Classification	Drug Derivative
Hancockiamide C is a phenylacetic piperazine natural products found in Aspergillus hancockii. Hancockiamide C is synthesized via the hkm biosynthetic gene cluster, involving NRPS Hkm11 and the acetyltransferase Hkm3. Hancockiamide C inhibits seed germination of Arabidopsis thaliana (MIC = 6.3 μg/mL), but shows no activity against Eragrostis tef seeds .

Cat. No.	Product Name	Chemical Structure

HY-W454945S

*tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d8*
tert-Butyl piperazine-1-carboxylate-2,2,3,3,5,5,6,6-d₈ is the deuterium labeled tert-Butyl piperazine-1-carboxylate .

HY-78871S

1-(Methyl-d3)piperazine
1-(Methyl-d₃)piperazine is the deuterium labeled N-Methylpiperazine .

HY-20128S

Piperazin-2-one-d6
Piperazin-2-one-d₆ is the deuterium labeled Piperazin-2-one (HY-20128). Piperazin-2-one is a piperazine ring derivative containing amide and ester carbonyl groups. As an important intermediate, Piperazin-2-one can be used for the synthesis of various active compounds .

HY-20797S

*1-BOC-4-(2-Hydroxyethyl)piperazine-d4*
1-BOC-4-(2-Hydroxyethyl)piperazine-d₄ is the deuterium labeled 1-BOC-4-(2-Hydroxyethyl)piperazine[1].

HY-W578976S

*N-Boc-piperazine-d4*
N-Boc-piperazine-d₄ is the deuterium labeled N-Boc-piperazine.

HY-W714523

*1-Bis(4-fluorophenyl)methyl Piperazine-d8*
1-Bis(4-fluorophenyl)methyl Piperazine-d₈ is the deuterium labeled 1-(Bis(4-fluorophenyl)methyl)piperazine (HY-W009293).

HY-W754764S

11-(4-Nitrosopiperazin-1-yl)dibenzo[b,f][1,4]thiazepine-d8
11-(4-Nitrosopiperazin-1-yl)dibenzo[b,f][1,4]thiazepine-d₈ (Nitroso aryl piperazine-d₈) is deuterium labeled Nitroso aryl piperazine .

HY-W009293S

*1-(Bis(4-fluorophenyl)methyl)piperazine-d4*
1-(Bis(4-fluorophenyl)methyl)piperazine-d₄ (N-(4,4-Difluorobenzhydryl)piperazine-d₄) is the deuterium labeled 1-(Bis(4-fluorophenyl)methyl)piperazine.

HY-W740746

*1-(2-Hydroxyethyl)piperazine-d4*
1-(2-Hydroxyethyl)piperazine-d₄ is the deuterium labeled 1-(2-Hydroxyethyl)piperazine (HY-41939). 1-(2-Hydroxyethyl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W700119

*1-(4-Chlorobenzhydryl)piperazine-d8*
1-(4-Chlorobenzhydryl)piperazine-d₈ is the deuterium labeled 1-(4-Chlorobenzhydryl)piperazine (HY-W001978). 1-(4-Chlorobenzhydryl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W004148S

*1-(2-Pyrimidinyl)piperazine-d8 dihydrochloride*
1-(2-Pyrimidinyl)piperazine-d₈ (2-Piperazinylpyrimidine-d₈) dihydrochloride is deuterium-labeled 1-(2-Pyrimidinyl)piperazine dihydrochloride (HY-W004148) .

HY-W703800

1-(Methyl-d3)-4-(2,3,4-trimethoxybenzyl)piperazine
1-(Methyl-d₃)-4-(2,3,4-trimethoxybenzyl)piperazine is the deuterium labeled 1-methyl-4-(2,3,4-trimethoxybenzyl)piperazine dihydrochloride (Trimetazidine Impurity） (HY-Z3053).

HY-W140284S

*6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d8 hydrochloride*
6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate-d₈ (hydrochloride) is the deuterium labeled 6-(5-Chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl piperazine-1-carboxylate hydrochloride .

HY-W751523

*1,4-Bis(7-chloroquinolin-4-yl)piperazine-d8*
1,4-Bis(7-chloroquinolin-4-yl)piperazine-d₈ is the deuterium labeled 1,4-Bis(7-chloroquinolin-4-yl)piperazine (HY-W103104).

HY-32208S

*tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d4*
tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate-d₄ is the deuterium labeled tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate[1].

HY-B1397S

Cyclizine-d3
Cyclizine-d₃ is deuterium labeled Cyclizine. Cyclizine, a piperazine-derivative, is a potent and selective histamine H1 receptor antagonist. Cyclizine can be used for the research of nausea, vomiting, and dizziness .

HY-W701440

Piperazine-d8 TFA
Piperazine-d₈ TFA is the deuterium labeled Piperazine trifluoroacetate.

HY-W701429

*1,4-Bis(tert-butoxycarbonyl)piperazine-d8*
1,4-Bis(tert-butoxycarbonyl)piperazine-d₈ is the deuterium labeled 1,4-Bis(tert-butoxycarbonyl)piperazine (HY-42542).

HY-W703312

*1-(4-Bromo-2,5-dimethoxybenzyl)piperazine-d8*
1-(4-Bromo-2,5-dimethoxybenzyl)piperazine-d₈ is the deuterium labeled 1-(4-Bromo-2,5-dimethoxybenzyl)piperazine.

HY-W416548S

*1-Methyl-4-nitro piperazine-d11*
1-Methyl-4-nitro piperazine-d₁₁ is the deuterium labeled 1-Methyl-4-nitro piperazine. 1-Methyl-4-nitrosopiperazine (MNP; MeNP;N-Methyl-N'-nitrosopiperazine) is a potential impurity in sartans, non-steroidal anti-inflammatory drugs (NSAIDs), and thiazide diuretics .

HY-W704049

*tert-Butyl 4-(methyl-d3)piperazine-1-carboxylate*
tert-Butyl 4-(methyl-d₃)piperazine-1-carboxylate is the deuterium labeled tert-Butyl 4-methylpiperazine-1-carboxylate (HY-W050208).

HY-132403S

*4-(6-Nitro-3-pyridinyl)-piperazine-d4*
4-(6-Nitro-3-pyridinyl)-piperazine-2,2,6,6-d₄ is the deuterium labeled 4-(6-Nitro-3-pyridinyl)-piperazine-2,2,6,6 .

HY-W777094

*1-Acetyl-4-(4-hydroxyphenyl)piperazine-d8*
1-Acetyl-4-(4-hydroxyphenyl)piperazine-d₈ (Tetraethoxy C methyl propane-d₈) is the deuterium labeled 1-(4-(4-Hydroxyphenyl)piperazin-1-yl)ethanone (HY-W014037).

Cat. No.	Product Name		Classification

HY-W370953

Piperazine-CH2-propargyl		Alkynes
Piperazine-CH2-propargyl is a PROTAC linker that can be used in the synthesis of PROTACs.

HY-178067

*Phthalimidinoglutarimide-5-piperazine-COC2-alkynes*		Alkynes
Phthalimidinoglutarimide-5-piperazine-COC2-alkynes is a synthesized E3 ligase ligand-linker conjugate that can be used to synthesize PROTAC BCL-xL/BCL-w Degrader 1 (HY-178066). PROTAC BCL-xL/BCL-w Degrader 1 is a potent BCL-xL/BCL-w PROTAC degrader with anti-cancer activity .

Cat. No.	Product Name		Classification

HY-160552

244cis		Cationic Lipids
244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels .

HY-148830

Piperazine-bis(ethyl octadeca-9,12-dienoate)		Cationic Lipids
Piperazine-bis(ethyl octadeca-9,12-dienoate) is a cationic lipid extracted from patent WO2023036148A1, and can be used for the generation of Lipid nanoparticles (LNPs).

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