Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride

Art. -Nr.: HY-160244 Reinheit: 98.08%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride is the Pomalidomide (HY-10984)-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride can be connected to the ligand for protein by a linker to form PROTAC.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride Chemische Struktur

CAS. Nr. : 2758431-93-3

Größe	Verfügbarkeit	Menge

Kostenlose Probe (0.1 - 0.2 mg)	Jetzt bewerben
Kostenlose Probe (0.1 - 0.2 mg)	Jetzt bewerben
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	Auf Lager	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	Auf Lager	Estimated Time of Arrival: December 31
Solid
5 mg	Auf Lager	Estimated Time of Arrival: December 31
10 mg	Auf Lager	Estimated Time of Arrival: December 31
25 mg	Auf Lager	Estimated Time of Arrival: December 31
50 mg	Auf Lager	Estimated Time of Arrival: December 31
100 mg	Auf Lager	Estimated Time of Arrival: December 31
250 mg	Auf Lager	Estimated Time of Arrival: December 31
500 mg	Angebot einholen
1 g	Angebot einholen

or Massenanfrage

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

This product is a controlled substance and not for sale in your territory.

Other Forms of Pomalidomide 5'-piperazine-4-methylpiperidine dihydrochloride:

Pomalidomide 5'-piperazine-4-methylpiperidine Angebot einholen

Spezialitätsempfehlungen

•Related Screening Libraries:

•Related Small Molecules:

•Related Proteins:

Alle Ligands for E3 Ligase Isoform-spezifische Produkte anzeigen:

Alle Isoformen anzeigen

von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B KLHL41

Biologische Aktivität
Reinheit & Dokumentation
Kundenbewertung

Beschreibung

IC₅₀ & Target

Cereblon

Molekulargewicht

512.43

Formel

C₂₃H₃₁Cl₂N₅O₄

CAS. Nr.

2758431-93-3

Appearance

Solid

Color

Light yellow to brown

SMILES

O=C1NC(C(CC1)N2C(C3=CC=C(N4CCN(CC5CCNCC5)CC4)C=C3C2=O)=O)=O.Cl.Cl

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 50 mg/mL (97.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.9515 mL	9.7574 mL	19.5149 mL
5 mM	0.3903 mL	1.9515 mL	3.9030 mL
10 mM	0.1951 mL	0.9757 mL	1.9515 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner
Verdünnungsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Reinheit & Dokumentation

Purity: 98.08%

Select Batch:

Data Sheet (242 KB) SDS (252 KB)

COA (248 KB) HNMR (269 KB) LCMS (99 KB)

Handling Instructions (2659 KB)

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	1.9515 mL	9.7574 mL	19.5149 mL	48.7872 mL
	5 mM	0.3903 mL	1.9515 mL	3.9030 mL	9.7574 mL
	10 mM	0.1951 mL	0.9757 mL	1.9515 mL	4.8787 mL
	15 mM	0.1301 mL	0.6505 mL	1.3010 mL	3.2525 mL
	20 mM	0.0976 mL	0.4879 mL	0.9757 mL	2.4394 mL
	25 mM	0.0781 mL	0.3903 mL	0.7806 mL	1.9515 mL
	30 mM	0.0650 mL	0.3252 mL	0.6505 mL	1.6262 mL
	40 mM	0.0488 mL	0.2439 mL	0.4879 mL	1.2197 mL
	50 mM	0.0390 mL	0.1951 mL	0.3903 mL	0.9757 mL
	60 mM	0.0325 mL	0.1626 mL	0.3252 mL	0.8131 mL
	80 mM	0.0244 mL	0.1220 mL	0.2439 mL	0.6098 mL