Thalidomide-Piperazine-PEG2-NH2 hydrochloride
Thalidomide-Piperazine-PEG2-NH2 hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Thalidomide-Piperazine-PEG2-NH2 hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2357110-15-5
- Formula: C23H32ClN5O6
- Molecular Weight:509.99
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2357110-15-5
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Molecular Weight 509.99
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Formula C23H32ClN5O6
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SMILES
Cl.O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCN(CCOCCOCCN)CC4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)