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Cat. No.: HY-W904851

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Boc-Piperidine-piperazine-Cbz

Boc-Piperidine-piperazine-Cbz is a PROTAC linker that can be used in the synthesis of ZLC491 (HY-168162).

For research use only. We do not sell to patients.

CAS No.: 177276-40-3
Formula: C₂₂H₃₃N₃O₄
Molecular Weight:403.52

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Boc-Piperidine-piperazine-Cbz Chemical Structure

CAS No.: 177276-40-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Boc-Piperidine-piperazine-Cbz is a PROTAC linker that can be used in the synthesis of ZLC491 (HY-168162)^[1].

All PROTAC Linkers Isoforms :

Chemical Information

CAS No. 177276-40-3
Molecular Weight 403.52
Formula C₂₂H₃₃N₃O₄
SMILES

O=C(N1CCN(C2CCN(CC2)C(OC(C)(C)C)=O)CC1)OCC3=CC=CC=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhou L, et, al. Discovery of ZLC491 as a Potent, Selective, and Orally Bioavailable CDK12/13 PROTAC Degrader. J Med Chem. 2024 Oct 24;67(20):18247-18264. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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References

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Boc-Piperidine-piperazine-Cbz

All PROTAC Linkers Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Boc-Piperidine-piperazine-Cbz Related Classifications

HY-W904851 Related Classifications