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Cat. No.: HY-181736

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Pomalidomide-C2-piperazine-Boc

Pomalidomide-C2-piperazine-Boc is an E3 ligase ligand-linker conjugate that can be used to synthesize PROTACs, such as PROTAC BET Degrader-15 (HY-181729).

For research use only. We do not sell to patients.

CAS No.: 2461559-77-1
Formula: C₂₄H₃₁N₅O₆
Molecular Weight:485.53

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Pomalidomide-C2-piperazine-Boc Chemical Structure

CAS No.: 2461559-77-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Pomalidomide-C2-piperazine-Boc is an E3 ligase ligand-linker conjugate that can be used to synthesize PROTACs, such as PROTAC BET Degrader-15 (HY-181729).

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2461559-77-1
Molecular Weight 485.53
Formula C₂₄H₃₁N₅O₆
SMILES

O=C1N(C2CCC(NC2=O)=O)C(C3=CC=CC(NCCN4CCN(C(OC(C)(C)C)=O)CC4)=C31)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yu S, et al. Semi-rigid linkers improve the pharmacokinetic properties and therapeutic efficacy of BET PROTACs for cancer therapy. Eur J Med Chem. 2026;307:118644. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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