Thalidomide-(1-(3-pyrrolidinylmethyl)piperazine)
Thalidomide-(1-(3-pyrrolidinylmethyl)piperazine) is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
For research use only. We do not sell to patients.
- CAS No.: 2988889-44-5
- Formula: C22H27N5O4
- Molecular Weight:425.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
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Cereblon |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2988889-44-5
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Molecular Weight 425.48
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Formula C22H27N5O4
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SMILES
O=C1N(C(C2=C1C=CC(N3CCN(CC3)CC4CNCC4)=C2)=O)C(C(N5)=O)CCC5=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)