GNF-8625 monopyridin-N-piperazine hydrochloride
Based on 1 publication(s) in Google Scholar
GNF-8625 monopyridin-N-piperazine hydrochloride (TRKi-2), a TRK inhibitor, which is from the patent WO 2020038415 A1.
For research use only. We do not sell to patients.
- Purity : 99.74%
- CAS No.: 2412055-62-8
- Formula: C25H27ClFN7
- Molecular Weight:479.98
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) GNF-8625 monopyridin-N-piperazine hydrochloride
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Biological Activity
Description
Chemical Information
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CAS No. 2412055-62-8
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Appearance Solid
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Molecular Weight 479.98
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Formula C25H27ClFN7
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Color Light yellow to yellow
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SMILES
FC1=CC([C@@H]2N(C3=NN4C(C=C3)=NC=C4C5=NC(N6CCNCC6)=CC=C5)CCC2)=CC=C1.[H]Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Publications (1)
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Journal Impact Factor
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Most Recent
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bioRxiv
2025 Jun 24:2025.06.18.660465. PMID: 40666929
Solvent & Solubility
In Vitro:
DMSO : 6.67 mg/mL (13.90 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (276 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.0834 mL | 10.4171 mL | 20.8342 mL | 52.0855 mL |
| 5 mM | 0.4167 mL | 2.0834 mL | 4.1668 mL | 10.4171 mL | |
| 10 mM | 0.2083 mL | 1.0417 mL | 2.0834 mL | 5.2086 mL |
GNF-8625 monopyridin-N-piperazine hydrochloride Related Classifications
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