1. Neuronal Signaling
    Protein Tyrosine Kinase/RTK
  2. Trk Receptor
  3. TrkA-IN-1

TrkA-IN-1 

Cat. No.: HY-129634 Purity: 96.15%
Handling Instructions

TrkA-IN-1 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 of 99 nM in a cell-based assay. TrkA-IN-1 has analgesic activity.

For research use only. We do not sell to patients.

TrkA-IN-1 Chemical Structure

TrkA-IN-1 Chemical Structure

CAS No. : 1680179-43-4

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 385 In-stock
Estimated Time of Arrival: December 31
5 mg USD 350 In-stock
Estimated Time of Arrival: December 31
10 mg USD 580 In-stock
Estimated Time of Arrival: December 31
25 mg USD 1150 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

TrkA-IN-1 is a potent and selective Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 of 99 nM in a cell-based assay. TrkA-IN-1 has analgesic activity[1].

IC50 & Target[1]

TrkA

99 nM (IC50)

TrkB

81 μM (IC50)

TrkC

25 μM (IC50)

Molecular Weight

392.45

Formula

C₂₅H₂₀N₄O

CAS No.

1680179-43-4

SMILES

O=C(NC1=CN=C(C)N=C1C2=CC=CC=C2)NC3C4=C(C5=C3C=CC=C5)C=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 8.33 mg/mL (21.23 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5481 mL 12.7405 mL 25.4810 mL
5 mM 0.5096 mL 2.5481 mL 5.0962 mL
10 mM 0.2548 mL 1.2740 mL 2.5481 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

TrkA-IN-1Trk ReceptorTropomyosin related kinase receptorInhibitorinhibitorinhibit

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TrkA-IN-1
Cat. No.:
HY-129634
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