1. Neuronal Signaling Protein Tyrosine Kinase/RTK
  2. Trk Receptor
  3. PF-06273340

PF-06273340 

Cat. No.: HY-122616 Purity: ≥98.0%
COA Handling Instructions

PF-06273340 is a potent, selective, orally bioavailable and peripherally restricted pan Trk inhibitor.

For research use only. We do not sell to patients.

PF-06273340 Chemical Structure

PF-06273340 Chemical Structure

CAS No. : 1402438-74-7

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1 mg USD 120 In-stock
5 mg USD 350 In-stock
10 mg USD 580 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

PF-06273340 is a potent, selective, orally bioavailable and peripherally restricted pan Trk inhibitor[1].

IC50 & Target

TRK

 

Molecular Weight

479.92

Formula

C23H22ClN7O3

CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

O=C(NC1=CC(C(C2=CN(C(C)(C)CO)C3=NC(N)=NC=C32)=O)=CN=C1)CC4=NC=C(Cl)C=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

References
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PF-06273340 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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Product Name:
PF-06273340
Cat. No.:
HY-122616
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