1. Neuronal Signaling Protein Tyrosine Kinase/RTK
  2. Trk Receptor
  3. Tavilermide

Tavilermide  (Synonyms: MIM-D3)

Cat. No.: HY-17622 Purity: 98.98%
COA Handling Instructions

Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.

For research use only. We do not sell to patients.

Tavilermide Chemical Structure

Tavilermide Chemical Structure

CAS No. : 263251-78-1

Size Price Stock Quantity
1 mg USD 180 In-stock
5 mg USD 540 In-stock
10 mg USD 900 In-stock
50 mg USD 2700 In-stock
100 mg USD 3960 In-stock
200 mg   Get quote  
500 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 2 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Tavilermide is a selective, partial agonist of TrkA, or a nerve growth factor (NGF) mimetic.

IC50 & Target


In Vitro

Tavilermide (MIM-D3) is a tyrosine kinase TrkA receptor agonist, which can be used to treat dry eye.Tavilermide is a proteolytically stable, cyclic peptidomimetic that has been shown to be a partial TrkA receptor agonist. Tavilermide demonstrates activities similar to NGF (but does not bind to the p75NTR receptor) and can potentiate the effects of suboptimal concentrations of NGF[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight









Room temperature in continental US; may vary elsewhere.

Powder -20°C 3 years
4°C 2 years
In solvent -80°C 2 years
-20°C 1 year
Solvent & Solubility
In Vitro: 

NH4OH : 50 mg/mL (86.13 mM; ultrasonic and adjust pH to 10 with NH4OH)

H2O : 2 mg/mL (3.45 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.7225 mL 8.6127 mL 17.2253 mL
5 mM 0.3445 mL 1.7225 mL 3.4451 mL
10 mM 0.1723 mL 0.8613 mL 1.7225 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  50% PEG300    50% Saline

    Solubility: 25 mg/mL (43.06 mM); Suspended solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  0.5% CMC-Na/saline water

    Solubility: 10 mg/mL (17.23 mM); Suspended solution; Need ultrasonic

  • 3.

    Add each solvent one by one:  PBS

    Solubility: 4.17 mg/mL (7.18 mM); Clear solution; Need ultrasonic and warming and heat to 60°C

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation
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Tavilermide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

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