2. PROTAC
  3. PROTAC Linkers
  4. Boc-piperazine-benzoic acid

Boc-piperazine-benzoic acid 

Cat. No.: HY-W013249 Purity: ≥97.0%
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Boc-piperazine-benzoic acid is a PROTAC linker and can be used in the synthesis of PROTACs, such as PROTAC androgen receptor (AR) degrader ARD-2128 (HY-13229).

For research use only. We do not sell to patients.

Boc-piperazine-benzoic acid Chemical Structure

Boc-piperazine-benzoic acid Chemical Structure

CAS No. : 162046-66-4

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Based on 1 publication(s) in Google Scholar

Boc-piperazine-benzoic acid Related Antibodies

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Description

Boc-piperazine-benzoic acid is a PROTAC linker and can be used in the synthesis of PROTACs, such as PROTAC androgen receptor (AR) degrader ARD-2128 (HY-13229)[1].

In Vitro

ARD-2128 is a highly potent, orally bioavailable PROTAC androgen receptor (AR) degrader. ARD-2128 effectively reduces AR protein, suppresses AR-regulated genes in tumor tissues, and inhibits growth of tumor without signs of toxicity. ARD-2128 has the potential for the research of the prostate cancer[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Boc-piperazine-benzoic acid Related Antibodies
Molecular Weight

306.36

Formula

C16H22N2O4
CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C(O)C1=CC=C(N2CCN(C(OC(C)(C)C)=O)CC2)C=C1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: 97.42%

COA (245 KB)

Handling Instructions (2659 KB)
References
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Boc-piperazine-benzoic acid Related Classifications

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Boc-piperazine-benzoic acid162046-66-4PROTAC LinkerslinkerdegradertumorprostatecancerInhibitorinhibitorinhibit

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