1-(4-Chlorobenzhydryl)piperazine
Based on 1 Customer Validation
1-(4-Chlorobenzhydryl)piperazine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
For research use only. We do not sell to patients.
- Purity: 99.95%
- CAS No.: 303-26-4
- Formula: C17H19ClN2
- Molecular Weight:286.80
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Huh-7 | CC50 |
10.4 μM
Compound: Rac-1
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Cytotoxicity against human Huh7.5.1 cells assessed as ATP level by luminescence analysis
Cytotoxicity against human Huh7.5.1 cells assessed as ATP level by luminescence analysis
|
[PMID: 26599718] |
1-(4-Chlobenzhydryl)piperazine is an inactive metabolite of meclizine and chlorcyclizine. It has also been found as an impurity in commercial preparations of hydroxyzine and cetirizine. 1-(4-Chlorobenzhydryl)piperazine has been used in the synthesis of voltage-gated sodium channel 1.7 (Nav1.7) inhibitors, anticancer agents, and antihistamines.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 303-26-4
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Appearance Solid
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Molecular Weight 286.80
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Formula C17H19ClN2
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Color White to off-white
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SMILES
ClC1=CC=C(C=C1)C(C2=CC=CC=C2)N3CCNCC3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (435.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (245 KB)
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SDS (719 KB)
- English - EN (719 KB)
- Français - FR (719 KB)
- Deutsch - DE (719 KB)
- Norwegian - NO (719 KB)
- Español - ES (719 KB)
- Swedish - SV (719 KB)
- Italian - IT (719 KB)
- Korean - KR (719 KB)
- Portuguese - PT (719 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4868 mL | 17.4338 mL | 34.8675 mL | 87.1688 mL |
| 5 mM | 0.6974 mL | 3.4868 mL | 6.9735 mL | 17.4338 mL | |
| 10 mM | 0.3487 mL | 1.7434 mL | 3.4868 mL | 8.7169 mL | |
| 15 mM | 0.2325 mL | 1.1623 mL | 2.3245 mL | 5.8113 mL | |
| 20 mM | 0.1743 mL | 0.8717 mL | 1.7434 mL | 4.3584 mL | |
| 25 mM | 0.1395 mL | 0.6974 mL | 1.3947 mL | 3.4868 mL | |
| 30 mM | 0.1162 mL | 0.5811 mL | 1.1623 mL | 2.9056 mL | |
| 40 mM | 0.0872 mL | 0.4358 mL | 0.8717 mL | 2.1792 mL | |
| 50 mM | 0.0697 mL | 0.3487 mL | 0.6974 mL | 1.7434 mL | |
| 60 mM | 0.0581 mL | 0.2906 mL | 0.5811 mL | 1.4528 mL | |
| 80 mM | 0.0436 mL | 0.2179 mL | 0.4358 mL | 1.0896 mL | |
| 100 mM | 0.0349 mL | 0.1743 mL | 0.3487 mL | 0.8717 mL |