1. GPCR/G Protein
    Neuronal Signaling
    Immunology/Inflammation
  2. Histamine Receptor
  3. Cetirizine

Cetirizine 

Cat. No.: HY-17042
Handling Instructions

Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

For research use only. We do not sell to patients.

Cetirizine Chemical Structure

Cetirizine Chemical Structure

CAS No. : 83881-51-0

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Top Publications Citing Use of Products

Publications Citing Use of MCE Cetirizine

    Cetirizine purchased from MCE. Usage Cited in: Pharmacol Res. 2017 Nov;125(Pt B):150-160.

    The IL-33 production in different treatment groups is determined in rat skin by immunohistochemistry assay.
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    Description

    Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

    IC50 & Target

    H1 receptor

     

    In Vitro
    In Vivo
    Clinical Trial
    Molecular Weight

    388.89

    Formula

    C₂₁H₂₅ClN₂O₃

    CAS No.

    83881-51-0

    SMILES

    O=C(O)COCCN1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Solvent & Solubility
    In Vivo:
    • 1.

      Cetirizine is dissolved in PBS[6].

    References
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    Keywords:

    CetirizineHistamine ReceptorhistamineSARARIL-1βGM-CSFIL-8SeasonalallergicrhinitisInhibitorinhibitorinhibit

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    Cat. No.:
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