Cetirizine-d4
Based on 1 Customer Validation
Cetirizine-d4 is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.0%
- CAS. Nr.: 1219803-84-5
- Formel: C21H21D4ClN2O3
- Molecular Weight:392.91
-
Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
-
Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle Histamine Receptor Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
H1 Receptor |
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS. Nr. 1219803-84-5
-
Unlabeled Cas 83881-52-1
-
Appearance Solid
-
Molecular Weight 392.91
-
Formel C21H21D4ClN2O3
-
Color White to off-white
-
SMILES
O=C(O)COC([2H])([2H])C([2H])([2H])N1CCN(C(C2=CC=C(Cl)C=C2)C3=CC=CC=C3)CC1
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
DMSO : 250 mg/mL (636.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
-
Data Sheet (271 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
Verweise
[1]. Caroline M. Spencer, et al. Cetirizine. Drugs 46 (6): 1055•1080, 1993.
[2]. Shih MY, et al. Influence of cetirizine and levocetirizine on two cytokines secretion in human airway epithelial cells. Allergy Asthma Proc. 2008 Sep-Oct;29(5):480-5. [Content Brief]
[3]. Shimizu T, et al. Cetirizine, an H1-receptor antagonist, suppresses the expression of macrophage migration inhibitory factor: its potential anti-inflammatory action. Clin Exp Allergy. 2004 Jan;34(1):103-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5451 mL | 12.7256 mL | 25.4511 mL | 63.6278 mL |
| 5 mM | 0.5090 mL | 2.5451 mL | 5.0902 mL | 12.7256 mL | |
| 10 mM | 0.2545 mL | 1.2726 mL | 2.5451 mL | 6.3628 mL | |
| 15 mM | 0.1697 mL | 0.8484 mL | 1.6967 mL | 4.2419 mL | |
| 20 mM | 0.1273 mL | 0.6363 mL | 1.2726 mL | 3.1814 mL | |
| 25 mM | 0.1018 mL | 0.5090 mL | 1.0180 mL | 2.5451 mL | |
| 30 mM | 0.0848 mL | 0.4242 mL | 0.8484 mL | 2.1209 mL | |
| 40 mM | 0.0636 mL | 0.3181 mL | 0.6363 mL | 1.5907 mL | |
| 50 mM | 0.0509 mL | 0.2545 mL | 0.5090 mL | 1.2726 mL | |
| 60 mM | 0.0424 mL | 0.2121 mL | 0.4242 mL | 1.0605 mL | |
| 80 mM | 0.0318 mL | 0.1591 mL | 0.3181 mL | 0.7953 mL | |
| 100 mM | 0.0255 mL | 0.1273 mL | 0.2545 mL | 0.6363 mL |
Cetirizine-d4 Related Classifications
HY-17042S Related Classifications
Powered by Bioz