1. GPCR/G Protein
    Neuronal Signaling
    Immunology/Inflammation
  2. Histamine Receptor
  3. Cetirizine D8 dihydrochloride

Cetirizine D8 dihydrochloride 

Cat. No.: HY-17042AS1
Handling Instructions

Cetirizine D8 dihydrochloride is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

For research use only. We do not sell to patients.

Cetirizine D8 dihydrochloride Chemical Structure

Cetirizine D8 dihydrochloride Chemical Structure

CAS No. : 2070015-04-0

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Description

Cetirizine D8 dihydrochloride is a deuterium labeled Cetirizine. Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine, is a specific, orally active and long-acting histamine H1-receptor antagonist. Cetirizine marks antiallergic properties and inhibits eosinophil chemotaxis during the allergic response[1][2][3].

IC50 & Target

H1 receptor

 

Molecular Weight

469.86

Formula

C₂₁H₁₉D₈Cl₃N₂O₃

CAS No.

2070015-04-0

SMILES

ClC1=CC=C(C(N2C([2H])([2H])C([2H])([2H])N(CCOCC(O)=O)C([2H])([2H])C2([2H])[2H])C3=CC=CC=C3)C=C1.Cl.Cl

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

Cetirizine D8Cetirizine D 8Cetirizine D-8Histamine ReceptorhistamineSARARIL-1βGM-CSFIL-8SeasonalallergicrhinitisInhibitorinhibitorinhibit

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Cetirizine D8 dihydrochloride
Cat. No.:
HY-17042AS1
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